protein arginine methyltransferase 5

Synonym

SKB1 homolog (S. pombe), Shk1 kinase-binding protein 1 homolog, Protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, skb1 (S. pombe) homolog, protein arginine methyltransferase 5, PRMT5, SKB1, HRMT1L5, IBP72, SKB1Hs, JBP1, Jak-binding protein 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:169.50

cerebellum:176.30

brain stem:-

corpus callosum/glia:699.90

pineal gland:-

peripheral nerve:30.70

spine:-

retina:118.60

eye:76.40

artery/aorta:269.80

vein:133.30

lymphnode:111.20

peripheral blood:127.50

spleen:208

thymus:219

bone marrow:-

adipose:201.70

bone:191.90

skin:120

GeneChip

cerebrum:6.49

cerebellum:6.41

brain stem:6.58

corpus callosum/glia:6.32

pineal gland:-

peripheral nerve:7.07

spine:6.37

retina:-

eye:-

artery/aorta:6.77

vein:6.40

lymphnode:6.45

peripheral blood:-

spleen:6.23

thymus:7.03

bone marrow:6.40

adipose:6.76

bone:-

skin:7.23

CAGE

cerebrum:2.75

cerebellum:-

brain stem:2.75

corpus callosum/glia:2.81

pineal gland:2.67

peripheral nerve:-

spine:2.37

retina:-

eye:-

artery/aorta:2.79

vein:2.56

lymphnode:2.87

peripheral blood:-

spleen:2.62

thymus:2.88

bone marrow:-

adipose:2.59

bone:-

skin:-

RNA-seq

cerebrum:0.61

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.98

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.02

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:164

placenta:116.60

prostate:191.50

ovary:74.50

testis:199

heart:178.80

muscle:40.20

esophagus:342.80

stomach:85

intestine:194.40

colon:110.20

liver/hepato:126.70

lung:92.90

bladder:376.80

kidney:249.50

pituitary:-

thyroid/parathyroid:327.50

adrenal gland:406.30

pancreas:35.60

breast:158

salivary:-

GeneChip

uterus:7.16

placenta:6.79

prostate:7.45

ovary:7.52

testis:7.53

heart:6.54

muscle:7.09

esophagus:7.40

stomach:6.57

intestine:6.78

colon:6.89

liver/hepato:6.27

lung:6.29

bladder:-

kidney:7

pituitary:6.64

thyroid/parathyroid:6.86

adrenal gland:6.36

pancreas:6.83

breast:7.09

salivary:6.80

CAGE

uterus:2.80

placenta:3.08

prostate:3.06

ovary:3.16

testis:3.22

heart:2.94

muscle:3.38

esophagus:3.24

stomach:-

intestine:2.46

colon:2.91

liver/hepato:2.93

lung:2.59

bladder:2.97

kidney:3.11

pituitary:2.61

thyroid/parathyroid:3.33

adrenal gland:-

pancreas:3.13

breast:2.79

salivary:3.01

RNA-seq

uterus:-

placenta:-

prostate:1.66

ovary:2.06

testis:2.02

heart:0.51

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:1.45

liver/hepato:0.00

lung:1.26

bladder:-

kidney:0.69

pituitary:-

thyroid/parathyroid:1.74

adrenal gland:1.15

pancreas:-

breast:1.16

salivary:-

IDs

Refseq ID	NM_001039619
Gene ID	10419
Unigene ID	Hs.367854
Probe set ID	217786_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000100462
GTEx ID	ENSG00000100462

Orthologous Gene

Mouse[1]	NM_013768
Rat[1]	NM_001108867

Chromosomal Region

14q11.2 [23,389,720 - 23,398,794]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0008283	cell proliferation
GO:0042118	endothelial cell activation
GO:0010467	gene expression
GO:0043985	histone H4-R3 methylation
GO:0034660	ncRNA metabolic process
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0018216	peptidyl-arginine methylation
GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine
GO:0035246	peptidyl-arginine N-methylation
GO:0007088	regulation of mitosis
GO:0016070	RNA metabolic process
GO:0000387	spliceosomal snRNP assembly
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005634	nucleus
GO:0043234	protein complex

Molecular Function

GO:0003682	chromatin binding
GO:0008469	histone-arginine N-methyltransferase activity
GO:0008168	methyltransferase activity
GO:0005515	protein binding
GO:0035243	protein-arginine omega-N symmetric methyltransferase activity
GO:0043021	ribonucleoprotein binding

protein arginine methyltransferase 5

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function