interferon induced transmembrane protein 2 (1-8D)

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Synonym

Interferon-induced transmembrane protein 2, Interferon-inducible protein 1-8D, IFITM2, interferon induced transmembrane protein 2 (1-8D), 1-8D

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:7.89 cerebellum:6.97 brain stem:8.11 corpus callosum/glia:8.22 pineal gland:- peripheral nerve:10.18 spine:8.72 retina:- eye:- artery/aorta:10.56 vein:10.38 lymphnode:9.80 peripheral blood:- spleen:10.64 thymus:8.83 bone marrow:10 adipose:10.42 bone:- skin:9.58
CAGE cerebrum:4.66 cerebellum:- brain stem:4.98 corpus callosum/glia:4.61 pineal gland:4.90 peripheral nerve:- spine:5.55 retina:- eye:- artery/aorta:6.33 vein:5.88 lymphnode:6.72 peripheral blood:- spleen:7.64 thymus:4.56 bone marrow:- adipose:6.77 bone:- skin:-
RNA-seq cerebrum:6.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:9.21 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:9.13 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:10.48 placenta:9.34 prostate:9.57 ovary:10.67 testis:8.62 heart:10.16 muscle:8.12 esophagus:8.95 stomach:9.60 intestine:9.51 colon:9.77 liver/hepato:10.14 lung:10.73 bladder:- kidney:9.45 pituitary:8.14 thyroid/parathyroid:9.62 adrenal gland:9.90 pancreas:9.17 breast:9.87 salivary:8.13
CAGE uterus:6.31 placenta:6.00 prostate:6.25 ovary:6.87 testis:5.39 heart:6.50 muscle:6.10 esophagus:6.24 stomach:- intestine:5.15 colon:5.42     liver/hepato:7.82    lung:7.09 bladder:6.79 kidney:6.57 pituitary:5.10 thyroid/parathyroid:6.56 adrenal gland:- pancreas:5.54 breast:7.22 salivary:4.29
RNA-seq uterus:- placenta:- prostate:8.04 ovary:8.87 testis:7.88 heart:6.60 muscle:6.44 esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:9.20        lung:10.22    bladder:- kidney:8.16 pituitary:- thyroid/parathyroid:7.40 adrenal gland:9.34 pancreas:- breast:7.31 salivary:-

Gene Information

IDs

Refseq ID NM_006435
Gene ID 10581
Unigene ID -
Probe set ID 201315_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000185201
GTEx ID ENSG00000185201

Orthologous Gene

Mouse[5]  NM_001112715, NM_026820, NM_025378, NM_030694, NM_028968
Rat[1]  NM_001106314, NM_030833, NM_001136124, NM_030694, NM_028968

Chromosomal Region

11p15.5  [307,631  -  315,272]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1906403
3935435
6548414
12477932
15231747
15489334
16169070
19544527
20534863
20628624
20972266
21139048
21177806
21319273
21890473
21906983
21963094
21987572
22363774
23376165
23720721
24076421

Gene Ontology  (GO ID)

Biological Process

GO:0019221  cytokine-mediated signaling pathway
GO:0051607  defense response to virus
GO:0006955  immune response
GO:0045071  negative regulation of viral genome replication
GO:0046597  negative regulation of virion penetration into host cell
GO:0034341  response to interferon-gamma
GO:0009615  response to virus
GO:0060337  type I interferon-mediated signaling pathway

Cellular Component

GO:0016021  integral to membrane
GO:0005886  plasma membrane