ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

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Synonym

ST6GalNAc II, ST6GalNA II, SIATL1, Sialyltransferase 7B, SThM, STHM, GalNAc alpha-2,6-sialyltransferase II, ST6GalNAII, sialyltransferase-like 1, SIAT7B, ST6GALNAC2, SIAT7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:153.40 spine:- retina:237.30 eye:41.10 artery/aorta:- vein:- lymphnode:- peripheral blood:18.20 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:38.40
GeneChip cerebrum:5.66 cerebellum:5.58 brain stem:5.63 corpus callosum/glia:6.04 pineal gland:- peripheral nerve:8.26 spine:6.22 retina:- eye:- artery/aorta:6.25 vein:5.86 lymphnode:5.82 peripheral blood:- spleen:5.54 thymus:5.33 bone marrow:5.80 adipose:6.32 bone:- skin:7.05
CAGE cerebrum:0.72 cerebellum:- brain stem:1.37 corpus callosum/glia:2.29 pineal gland:1.62 peripheral nerve:- spine:1.92 retina:- eye:- artery/aorta:1.82 vein:2.13 lymphnode:1.88 peripheral blood:- spleen:0.71 thymus:0.61 bone marrow:- adipose:1.95 bone:- skin:-
RNA-seq cerebrum:0.93 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.63 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.38 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:18.20 prostate:33.80 ovary:- testis:30.30 heart:25.50 muscle:80.40 esophagus:- stomach:- intestine:32.40 colon:25.40     liver/hepato:-        lung:44    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:327.50 adrenal gland:- pancreas:8.90 breast:65.10 salivary:-
GeneChip uterus:6.12 placenta:6.49 prostate:6.25 ovary:7.10 testis:8.79 heart:6.17 muscle:6.69 esophagus:6.95 stomach:6.06 intestine:6.51 colon:6.67 liver/hepato:5.71 lung:6.93 bladder:- kidney:6.68 pituitary:5.57 thyroid/parathyroid:7.43 adrenal gland:5.78 pancreas:5.84 breast:7.28 salivary:6.64
CAGE uterus:2.11 placenta:3.26 prostate:2.43 ovary:2.15 testis:2.59 heart:1.85 muscle:2.24 esophagus:3.27 stomach:- intestine:1.37 colon:2.01     liver/hepato:1.01    lung:3.08 bladder:2.29 kidney:2.74 pituitary:1.15 thyroid/parathyroid:3.23 adrenal gland:- pancreas:1.59 breast:2.11 salivary:1.95
RNA-seq uterus:- placenta:- prostate:3.04 ovary:2.81 testis:3.68 heart:1.06 muscle:3.76 esophagus:- stomach:- intestine:- colon:2.09     liver/hepato:1.15        lung:3.12    bladder:- kidney:2.90 pituitary:- thyroid/parathyroid:3.14 adrenal gland:0.68 pancreas:- breast:2.38 salivary:-

Gene Information

IDs

Refseq ID NM_006456
Gene ID 10610
Unigene ID Hs.592105
Probe set ID 204542_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000070731
GTEx ID ENSG00000070731

Orthologous Gene

Mouse[2]  NM_009180
Rat[1]  NM_001031652

Chromosomal Region

17q25.1  [74,561,461  -  74,582,145]

Gene Family (Interpro ID)

IPR001675  Glycosyl transferase, family 29
IPR012163  Sialyltransferase

Link to Pubmed  (Pubmed ID)

8125298
10742600
12477932
14702039
15231748
15489334
17418236
17480010
19170967
19357720
23548905
24398680

Gene Ontology  (GO ID)

Biological Process

GO:0044267  cellular protein metabolic process
GO:0016266  O-glycan processing
GO:0043687  post-translational protein modification

Cellular Component

GO:0000139  Golgi membrane
GO:0030173  integral to Golgi membrane

Molecular Function

GO:0008373  sialyltransferase activity