CUG triplet repeat, RNA binding protein 1

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Synonym

BRUNOL2, CUG triplet repeat, RNA binding protein 1, EDEN-BP, Deadenylation factor CUG-BP, 50 kDa Nuclear polyadenylated RNA-binding protein, CUGBP, NAB50, RNA-binding protein BRUNOL-2, CUG-BP, CUGBP1, hNab50, CUG triplet repeat RNA-binding protein 1, CUG-BP1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:179 cerebellum:377.80 brain stem:- corpus callosum/glia:87.50 pineal gland:445 peripheral nerve:30.70 spine:- retina:118.60 eye:82.30 artery/aorta:119.90 vein:66.60 lymphnode:111.20 peripheral blood:54.70 spleen:245.80 thymus:219 bone marrow:137.80 adipose:80.70 bone:89.60 skin:96
GeneChip cerebrum:5.11 cerebellum:5.66 brain stem:4.97 corpus callosum/glia:4.97 pineal gland:- peripheral nerve:5.57 spine:5.16 retina:- eye:- artery/aorta:5.05 vein:5.11 lymphnode:5.04 peripheral blood:- spleen:5.60 thymus:5.86 bone marrow:5.44 adipose:5.08 bone:- skin:4.95
CAGE cerebrum:4.06 cerebellum:- brain stem:3.48 corpus callosum/glia:3.70 pineal gland:4.14 peripheral nerve:- spine:3.60 retina:- eye:- artery/aorta:4.05 vein:3.70 lymphnode:3.68 peripheral blood:- spleen:3.52 thymus:3.47 bone marrow:- adipose:3.80 bone:- skin:-
RNA-seq cerebrum:0.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.97 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.43 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:191.40 placenta:36.40 prostate:- ovary:149.10 testis:86.50 heart:38.30 muscle:- esophagus:- stomach:106.20 intestine:64.80 colon:203.50     liver/hepato:179.40        lung:97.80    bladder:- kidney:52 pituitary:116 thyroid/parathyroid:327.50 adrenal gland:101.60 pancreas:26.70 breast:139.40 salivary:-
GeneChip uterus:5.49 placenta:5.26 prostate:5.51 ovary:5.33 testis:5.62 heart:5.17 muscle:5.62 esophagus:5.34 stomach:5.12 intestine:5.49 colon:5.31 liver/hepato:5.46 lung:5.15 bladder:- kidney:5.31 pituitary:5.44 thyroid/parathyroid:4.98 adrenal gland:5.31 pancreas:5.05 breast:5 salivary:4.87
CAGE uterus:3.77 placenta:3.60 prostate:3.71 ovary:3.57 testis:3.92 heart:3.86 muscle:4.06 esophagus:3.67 stomach:- intestine:3.43 colon:3.88     liver/hepato:4.00    lung:3.61 bladder:3.94 kidney:3.73 pituitary:3.72 thyroid/parathyroid:3.73 adrenal gland:- pancreas:3.77 breast:4.15 salivary:3.09
RNA-seq uterus:- placenta:- prostate:1.19 ovary:1.51 testis:1.93 heart:1.46 muscle:1.25 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.73        lung:1.53    bladder:- kidney:1.41 pituitary:- thyroid/parathyroid:1.41 adrenal gland:1.60 pancreas:- breast:1.45 salivary:-

Gene Information

IDs

Refseq ID NM_198700
Gene ID 10658
Unigene ID Hs.632137
Probe set ID 204113_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000149187
GTEx ID ENSG00000149187

Orthologous Gene

Mouse[20]  NM_017368, NM_198683
Rat[1]  NM_001025421, NM_198683

Chromosomal Region

11p11.2  [47,487,496  -  47,587,121]

Gene Family (Interpro ID)

IPR002343  Paraneoplastic encephalomyelitis antigen
IPR000504  RNA recognition motif, RNP-1

Link to Pubmed  (Pubmed ID)

8789448
8912635
8948631
9371827
10446244
10536163
10893231
11124939
11158314
11564876
11686919
12477932
12799066
14657503
14702039
14726956
14759258
15082764
15099703
15489334
15546872
15756469
16169070
16341674
16344560
16601207
16946708
17531403
17854664
17936705
18039683
18164289
18243120
18570922
19047369
19106619
19322201
19471022
19553194
19615732
19946888
20020773
20051426
20227387
20547756
20603324
20935630
20947024
21139048
21508681
21637851
21832049
21890473
21906983
21963094
22053931
22117072
22355723
22365833
22505724
22646166
22982313
23000965
23155001
23324604
23359188
24162737
24332808
24457600
24583282

Gene Ontology  (GO ID)

Biological Process

GO:0009790  embryonic development
GO:0007281  germ cell development
GO:0006397  mRNA processing
GO:0006376  mRNA splice site selection
GO:0040018  positive regulation of multicellular organism growth
GO:0043484  regulation of RNA splicing
GO:0016246  RNA interference
GO:0007286  spermatid development

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0030529  ribonucleoprotein complex

Molecular Function

GO:0042835  BRE binding
GO:0003729  mRNA binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0003723  RNA binding
GO:0031369  translation initiation factor binding
GO:0000900  translation repressor activity, nucleic acid binding