guanine nucleotide binding protein (G protein), beta 5

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Synonym

Gbeta5, Guanine nucleotide-binding protein subunit beta 5, GB5, FLJ37457, Transducin beta chain 5, GNB5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:88.90 cerebellum:201.50 brain stem:- corpus callosum/glia:29.20 pineal gland:296.70 peripheral nerve:30.70 spine:112.30 retina:237.30 eye:158.70 artery/aorta:- vein:- lymphnode:70.80 peripheral blood:36.40 spleen:75.60 thymus:38.70 bone marrow:19.70 adipose:- bone:38.40 skin:57.60
GeneChip cerebrum:7.39 cerebellum:8.39 brain stem:7.46 corpus callosum/glia:5.69 pineal gland:- peripheral nerve:6.81 spine:6.37 retina:- eye:- artery/aorta:6.64 vein:6.66 lymphnode:6.86 peripheral blood:- spleen:6.53 thymus:6.49 bone marrow:5.49 adipose:6.04 bone:- skin:5.91
CAGE cerebrum:4.32 cerebellum:- brain stem:3.43 corpus callosum/glia:2.80 pineal gland:4.71 peripheral nerve:- spine:3.10 retina:- eye:- artery/aorta:3.36 vein:3.02 lymphnode:3.16 peripheral blood:- spleen:2.99 thymus:3.09 bone marrow:- adipose:2.68 bone:- skin:-
RNA-seq cerebrum:3.95 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.34 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.28 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:10.90 prostate:11.30 ovary:111.80 testis:30.30 heart:12.80 muscle:- esophagus:342.80 stomach:- intestine:- colon:25.40     liver/hepato:21.10        lung:39.10    bladder:- kidney:124.80 pituitary:463.90 thyroid/parathyroid:- adrenal gland:50.80 pancreas:62.20 breast:- salivary:-
GeneChip uterus:6.99 placenta:5.28 prostate:6.74 ovary:7.43 testis:6.67 heart:6.28 muscle:5.16 esophagus:6.24 stomach:6.32 intestine:5.98 colon:5.94 liver/hepato:6.53 lung:5.92 bladder:- kidney:7.51 pituitary:7.29 thyroid/parathyroid:7.05 adrenal gland:6.34 pancreas:6.20 breast:6.48 salivary:5.85
CAGE uterus:3.64 placenta:2.28 prostate:3.48 ovary:4.11 testis:3.40 heart:3.33 muscle:1.92 esophagus:3.11 stomach:- intestine:1.99 colon:2.97     liver/hepato:3.41    lung:2.66 bladder:3.49 kidney:3.53 pituitary:3.58 thyroid/parathyroid:3.45 adrenal gland:- pancreas:3.29 breast:3.43 salivary:1.95
RNA-seq uterus:- placenta:- prostate:3.97 ovary:4.63 testis:4.32 heart:1.49 muscle:0.84 esophagus:- stomach:- intestine:- colon:3.14     liver/hepato:2.73        lung:2.25    bladder:- kidney:3.79 pituitary:- thyroid/parathyroid:3.45 adrenal gland:3.08 pancreas:- breast:2.22 salivary:-

Gene Information

IDs

Refseq ID NM_006578
Gene ID 10681
Unigene ID Hs.155090
Probe set ID 204000_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000069966
GTEx ID ENSG00000069966

Orthologous Gene

Mouse[2]  NM_010313, NM_138719
Rat[2]  NM_010313, NM_138719

Chromosomal Region

15q21.2  [52,413,117  -  52,483,566]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

8636150
8910430
9315921
9606987
9789084
10051672
10339615
10521509
10644457
11007869
11076863
11230166
11256614
11675383
12119397
12477932
12606627
14702039
15474482
15489334
15489336
16135253
16169070
16381901
16867977
16884933
18094259
19322201
19376773
19773279
20374718
21511947
21832049
21900206
21988832

Gene Ontology  (GO ID)

Biological Process

GO:0006184  GTP catabolic process
GO:0007603  phototransduction, visible light
GO:0022400  regulation of rhodopsin mediated signaling pathway
GO:0016056  rhodopsin mediated signaling pathway
GO:0007165  signal transduction

Cellular Component

GO:0005834  heterotrimeric G-protein complex
GO:0005634  nucleus

Molecular Function

GO:0003924  GTPase activity
GO:0004871  signal transducer activity