adenylate cyclase 1 (brain)

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Synonym

Adenylate cyclase type 1, Adenylate cyclase type I, adenylate cyclase 1 (brain), Ca(2+)/calmodulin-activated adenylyl cyclase, ATP pyrophosphate-lyase 1, ADCY1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:182.50 cerebellum:214.10 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:118.60 eye:146.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:7.91 cerebellum:9.36 brain stem:6.83 corpus callosum/glia:5.44 pineal gland:- peripheral nerve:5.03 spine:6.43 retina:- eye:- artery/aorta:4.43 vein:4.71 lymphnode:4.39 peripheral blood:- spleen:3.83 thymus:3.63 bone marrow:3.85 adipose:4.71 bone:- skin:4.18
CAGE cerebrum:2.77 cerebellum:- brain stem:1.69 corpus callosum/glia:1.66 pineal gland:2.47 peripheral nerve:- spine:1.17 retina:- eye:- artery/aorta:0.59 vein:0.47 lymphnode:0.15 peripheral blood:- spleen:0.09 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:3.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.44 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.43 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:- prostate:- ovary:- testis:26 heart:114.90 muscle:- esophagus:- stomach:- intestine:- colon:17     liver/hepato:52.80        lung:-    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:65.10 salivary:-
GeneChip uterus:5.02 placenta:3.87 prostate:5.58 ovary:4.05 testis:4.83 heart:5.05 muscle:5.85 esophagus:4.25 stomach:4.42 intestine:4.69 colon:4.22 liver/hepato:6.99 lung:4.06 bladder:- kidney:4.87 pituitary:5.39 thyroid/parathyroid:5.35 adrenal gland:5.14 pancreas:5.62 breast:5.16 salivary:4.09
CAGE uterus:0.77 placenta:0.54 prostate:1.06 ovary:0.32 testis:1.34 heart:0.69 muscle:1.02 esophagus:0.18 stomach:- intestine:0.07 colon:0.79     liver/hepato:0    lung:0.48 bladder:0.33 kidney:0.39 pituitary:0.90 thyroid/parathyroid:0.64 adrenal gland:- pancreas:1.87 breast:1.36 salivary:0
RNA-seq uterus:- placenta:- prostate:0.37 ovary:0.52 testis:1.03 heart:0.94 muscle:0.28 esophagus:- stomach:- intestine:- colon:0.43     liver/hepato:2.16        lung:0.17    bladder:- kidney:1.15 pituitary:- thyroid/parathyroid:0.81 adrenal gland:2.34 pancreas:- breast:0.62 salivary:-

Gene Information

IDs

Refseq ID NM_021116
Gene ID 107
Unigene ID Hs.192215
Probe set ID 213245_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000164742
GTEx ID ENSG00000164742

Orthologous Gene

Mouse[1]  NM_009622
Rat[1]  NM_001107239

Chromosomal Region

7p12.3  [45,613,739  -  45,762,715]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2121366
2165385
7937899
7959689
8314585
8476432
8663304
8692867
9417641
10089566
10807185
10808179
11299302
11549699
11884542
12477932
12503609
12626323
12690205
12743114
12853948
14702039
14993377
15133516
15361543
16531006
17586501
19029295
19056867
19058789
19156168
19460752
19726641
19834535
20554763
23504261

Gene Ontology  (GO ID)

Biological Process

GO:0007189  activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007202  activation of phospholipase C activity
GO:0034199  activation of protein kinase A activity
GO:0007409  axonogenesis
GO:0006171  cAMP biosynthetic process
GO:0071377  cellular response to glucagon stimulus
GO:0007623  circadian rhythm
GO:0006112  energy reserve metabolic process
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0007193  inhibition of adenylate cyclase activity by G-protein signaling pathway
GO:0045087  innate immune response
GO:0007616  long-term memory
GO:0048011  nerve growth factor receptor signaling pathway
GO:0042493  response to drug
GO:0010226  response to lithium ion
GO:0007165  signal transduction
GO:0007268  synaptic transmission
GO:0055085  transmembrane transport
GO:0006833  water transport

Cellular Component

GO:0016021  integral to membrane
GO:0005634  nucleus
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0008294  calcium- and calmodulin-responsive adenylate cyclase activity
GO:0005516  calmodulin binding
GO:0046872  metal ion binding