transducer of ERBB2, 2

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Synonym

TROB2, transducer of ERBB2, 2, TOBL, TOB4, Tob2 protein, KIAA1663, bK223H9, TOB2, Transducer of erbB-2 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.80 cerebellum:7.75 brain stem:6.73 corpus callosum/glia:7.87 pineal gland:- peripheral nerve:7.67 spine:7.99 retina:- eye:- artery/aorta:7.69 vein:6.96 lymphnode:6.96 peripheral blood:- spleen:7.49 thymus:7.48 bone marrow:5.73 adipose:7.52 bone:- skin:7.39
CAGE cerebrum:3.40 cerebellum:- brain stem:3.39 corpus callosum/glia:3.65 pineal gland:3.72 peripheral nerve:- spine:3.41 retina:- eye:- artery/aorta:3.63 vein:3.45 lymphnode:2.65 peripheral blood:- spleen:2.82 thymus:3.00 bone marrow:- adipose:3.24 bone:- skin:-
RNA-seq cerebrum:3.25 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.37 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.48 placenta:6.59 prostate:8.10 ovary:7.72 testis:6.73 heart:7.43 muscle:7.97 esophagus:7.07 stomach:7.32 intestine:7.12 colon:7.05 liver/hepato:7.47 lung:7.71 bladder:- kidney:7.50 pituitary:7.09 thyroid/parathyroid:8.46 adrenal gland:7.84 pancreas:6.25 breast:7.49 salivary:6.16
CAGE uterus:3.05 placenta:2.54 prostate:2.98 ovary:3.51 testis:2.98 heart:3.26 muscle:3.50 esophagus:3.07 stomach:- intestine:3.29 colon:3.39     liver/hepato:2.51    lung:3.21 bladder:3.12 kidney:2.89 pituitary:2.73 thyroid/parathyroid:3.43 adrenal gland:- pancreas:2.71 breast:3.16 salivary:2.01
RNA-seq uterus:- placenta:- prostate:4.34 ovary:5.15 testis:4.22 heart:4.06 muscle:4.57 esophagus:- stomach:- intestine:- colon:4.37     liver/hepato:2.60        lung:4.01    bladder:- kidney:4.31 pituitary:- thyroid/parathyroid:5.09 adrenal gland:3.20 pancreas:- breast:4.31 salivary:-

Gene Information

IDs

Refseq ID NM_016272
Gene ID 10766
Unigene ID -
Probe set ID 222243_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000183864
GTEx ID ENSG00000183864

Orthologous Gene

Mouse[4]  NM_020507
Rat[1]  NM_001007146

Chromosomal Region

22q13.2  [41,829,496  -  41,843,027]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10591208
10602502
11258795
11260258
11429045
12135500
12477932
15461802
15489334
17785442
19322201
19760502
19940862
20360068
21242960
21726813
22252318
22561518

Gene Ontology  (GO ID)

Biological Process

GO:0007292  female gamete generation
GO:0008285  negative regulation of cell proliferation
GO:0045671  negative regulation of osteoclast differentiation
GO:0045778  positive regulation of ossification
GO:0010468  regulation of gene expression

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0042809  vitamin D receptor binding