NCK-associated protein 1

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Synonym

Membrane-associated protein HEM-2, FLJ11291, NAP125, HEM2, p125Nap1, NAP 1, MGC8981, NCKAP1, Nck-associated protein 1, KIAA0587, Nap1, NCK-associated protein 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:89.90 vein:66.60 lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:- bone:- skin:19.20
GeneChip cerebrum:8.99 cerebellum:8.92 brain stem:8.84 corpus callosum/glia:8.16 pineal gland:- peripheral nerve:9.02 spine:8.69 retina:- eye:- artery/aorta:8.98 vein:8.70 lymphnode:7.56 peripheral blood:- spleen:7.49 thymus:7.52 bone marrow:5.63 adipose:8.67 bone:- skin:9
CAGE cerebrum:4.67 cerebellum:- brain stem:4.25 corpus callosum/glia:3.89 pineal gland:4.48 peripheral nerve:- spine:4.37 retina:- eye:- artery/aorta:4.36 vein:3.41 lymphnode:3.38 peripheral blood:- spleen:3.61 thymus:2.70 bone marrow:- adipose:4.41 bone:- skin:-
RNA-seq cerebrum:5.75 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.89 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.48 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:14.60 prostate:22.50 ovary:- testis:4.30 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:10.60        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:18.60 salivary:-
GeneChip uterus:9.04 placenta:8.75 prostate:9.04 ovary:8.84 testis:8.11 heart:8.72 muscle:8.64 esophagus:9.11 stomach:8.52 intestine:8.69 colon:8.03 liver/hepato:7.54 lung:8.40 bladder:- kidney:8.33 pituitary:8.69 thyroid/parathyroid:8.89 adrenal gland:8.40 pancreas:8.14 breast:8.73 salivary:8.33
CAGE uterus:4.55 placenta:4.58 prostate:4.67 ovary:4.33 testis:3.93 heart:4.67 muscle:4.28 esophagus:4.91 stomach:- intestine:4.62 colon:4.34     liver/hepato:3.81    lung:4.22 bladder:4.79 kidney:4.53 pituitary:4.24 thyroid/parathyroid:4.57 adrenal gland:- pancreas:3.71 breast:4.35 salivary:3.98
RNA-seq uterus:- placenta:- prostate:6.18 ovary:5.62 testis:5.67 heart:5.85 muscle:5.94 esophagus:- stomach:- intestine:- colon:6.32     liver/hepato:4.03        lung:5.41    bladder:- kidney:5.77 pituitary:- thyroid/parathyroid:6.33 adrenal gland:5.13 pancreas:- breast:5.54 salivary:-

Gene Information

IDs

Refseq ID NM_013436
Gene ID 10787
Unigene ID Hs.603732
Probe set ID 207738_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000061676
GTEx ID ENSG00000061676

Orthologous Gene

Mouse[1]  NM_016965
Rat[1]  NM_031618

Chromosomal Region

2q32.1  [183,789,605  -  183,903,586]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8605018
8889548
9148763
9344857
9417078
9463375
9628581
10673335
11418237
12181570
12477932
14506234
14560022
14702039
15048123
15048733
15294869
15296760
15324660
15489334
15749123
16055720
17353931
18560548
18854154
19056867
21139048
21706016
21875946
21890473
21906983
22586326
22779921
22863883
23000965
24255178

Gene Ontology  (GO ID)

Biological Process

GO:0045176  apical protein localization
GO:0006915  apoptosis
GO:0045175  basal protein localization
GO:0007417  central nervous system development
GO:0010172  embryonic body morphogenesis
GO:0048617  embryonic foregut morphogenesis
GO:0035050  embryonic heart tube development
GO:0007492  endoderm development
GO:0030950  establishment or maintenance of actin cytoskeleton polarity
GO:0001701  in utero embryonic development
GO:0045087  innate immune response
GO:0030032  lamellipodium assembly
GO:0008078  mesodermal cell migration
GO:0001843  neural tube closure
GO:0048570  notochord morphogenesis
GO:0048340  paraxial mesoderm morphogenesis
GO:0050821  protein stabilization
GO:0032880  regulation of protein localization
GO:0001756  somitogenesis
GO:0007354  zygotic determination of anterior/posterior axis, embryo

Cellular Component

GO:0005829  cytosol
GO:0016021  integral to membrane
GO:0031258  lamellipodium membrane

Molecular Function

GO:0005515  protein binding