aldehyde dehydrogenase 1 family, member L1

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Synonym

aldehyde dehydrogenase 1 family, member L1, FTHFD, DKFZp781N0997, Aldehyde dehydrogenase 1 family member L1, formyltetrahydrofolate dehydrogenase, 10-FTHFDH, ALDH1L1, 10-formyltetrahydrofolate dehydrogenase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:61.60 cerebellum:88.20 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:- retina:118.60 eye:99.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:38.70 bone marrow:- adipose:40.30 bone:25.60 skin:28.80
GeneChip cerebrum:6.46 cerebellum:6.39 brain stem:6.48 corpus callosum/glia:6.30 pineal gland:- peripheral nerve:5.44 spine:6.55 retina:- eye:- artery/aorta:6.56 vein:5.35 lymphnode:5.87 peripheral blood:- spleen:5.42 thymus:6.31 bone marrow:5.61 adipose:7.40 bone:- skin:6.40
CAGE cerebrum:3.57 cerebellum:- brain stem:3.02 corpus callosum/glia:3.07 pineal gland:1.67 peripheral nerve:- spine:3.44 retina:- eye:- artery/aorta:2.94 vein:3.18 lymphnode:1.33 peripheral blood:- spleen:0.25 thymus:0.28 bone marrow:- adipose:3.69 bone:- skin:-
RNA-seq cerebrum:4.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.39 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.69 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:22.50 ovary:111.80 testis:30.30 heart:12.80 muscle:20.10 esophagus:- stomach:- intestine:- colon:59.40     liver/hepato:179.40        lung:29.30    bladder:- kidney:249.50 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:46.50 salivary:-
GeneChip uterus:5.74 placenta:5.42 prostate:6.20 ovary:5.85 testis:6.62 heart:5.83 muscle:7.61 esophagus:6.13 stomach:5.40 intestine:5.98 colon:5.92 liver/hepato:9.51 lung:5.71 bladder:- kidney:8.18 pituitary:5.55 thyroid/parathyroid:5.66 adrenal gland:6.64 pancreas:6.31 breast:6.01 salivary:7.92
CAGE uterus:2.02 placenta:0.08 prostate:2.48 ovary:2.67 testis:2.71 heart:2.43 muscle:3.90 esophagus:2.38 stomach:- intestine:0.33 colon:2.30     liver/hepato:5.33    lung:0.72 bladder:2.71 kidney:4.33 pituitary:1.55 thyroid/parathyroid:1.48 adrenal gland:- pancreas:3.34 breast:3.24 salivary:4.72
RNA-seq uterus:- placenta:- prostate:3.42 ovary:2.08 testis:2.46 heart:1.89 muscle:4.67 esophagus:- stomach:- intestine:- colon:2.40     liver/hepato:5.27        lung:1.01    bladder:- kidney:5.31 pituitary:- thyroid/parathyroid:2.56 adrenal gland:0.28 pancreas:- breast:4.92 salivary:-

Gene Information

IDs

Refseq ID NM_012190
Gene ID 10840
Unigene ID Hs.434435
Probe set ID 205208_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000144908
GTEx ID ENSG00000144908

Orthologous Gene

Mouse[2]  NM_027406
Rat[2]  NM_027406

Chromosomal Region

3q21.3  [125,822,412  -  125,916,837]

Gene Family (Interpro ID)

IPR009081  Acyl carrier protein-like

Link to Pubmed  (Pubmed ID)

2733692
7972060
8125298
10204077
12065246
12477932
12805405
17111379
17119116
17548676
17891500
18676680
18830263
18848533
19018242
19048631
19056867
19064578
19161160
19170196
19343046
19447584
19625176
19692168
19851296
19913121
19935739
19936946
20198315
20453000
20628086
20634891
20729910
20737570
20877624
21046559
21215736
21238436
21540484
21779486
21987076
22039442
22491060
22593801
23378610
24324551

Gene Ontology  (GO ID)

Biological Process

GO:0009258  10-formyltetrahydrofolate catabolic process
GO:0009058  biosynthetic process
GO:0006730  one-carbon metabolic process

Cellular Component

GO:0005739  mitochondrion

Molecular Function

GO:0003824  catalytic activity
GO:0016155  formyltetrahydrofolate dehydrogenase activity
GO:0016742  hydroxymethyl-, formyl- and related transferase activity
GO:0008168  methyltransferase activity
GO:0016620  oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor