AFG3 ATPase family gene 3-like 2 (yeast)

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Synonym

Paraplegin-like protein, FLJ25993, AFG3L2, AFG3 ATPase family gene 3-like 2 (yeast), AFG3-like protein 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.70 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:355.90 eye:76.40 artery/aorta:30 vein:- lymphnode:50.60 peripheral blood:18.20 spleen:- thymus:- bone marrow:19.70 adipose:80.70 bone:12.80 skin:52.80
GeneChip cerebrum:7.36 cerebellum:7.42 brain stem:7.37 corpus callosum/glia:7.21 pineal gland:- peripheral nerve:7.43 spine:7.23 retina:- eye:- artery/aorta:7.18 vein:7.16 lymphnode:7.27 peripheral blood:- spleen:7.05 thymus:7.25 bone marrow:7.26 adipose:7.15 bone:- skin:7.54
CAGE cerebrum:3.92 cerebellum:- brain stem:3.60 corpus callosum/glia:3.50 pineal gland:3.83 peripheral nerve:- spine:3.86 retina:- eye:- artery/aorta:3.81 vein:3.60 lymphnode:4.06 peripheral blood:- spleen:3.47 thymus:3.40 bone marrow:- adipose:3.44 bone:- skin:-
RNA-seq cerebrum:4.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.94 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:32.80 prostate:78.90 ovary:- testis:30.30 heart:76.60 muscle:40.20 esophagus:- stomach:- intestine:32.40 colon:17     liver/hepato:21.10        lung:34.20    bladder:251.20 kidney:93.60 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:17.80 breast:74.30 salivary:-
GeneChip uterus:7.05 placenta:6.90 prostate:7.16 ovary:7.29 testis:7.35 heart:7.99 muscle:8.73 esophagus:7.93 stomach:7.22 intestine:7.68 colon:7.54 liver/hepato:7.72 lung:6.96 bladder:- kidney:8.09 pituitary:7.53 thyroid/parathyroid:7.82 adrenal gland:7.35 pancreas:7.32 breast:7.45 salivary:7.61
CAGE uterus:3.46 placenta:3.47 prostate:3.45 ovary:3.53 testis:3.49 heart:4.91 muscle:4.96 esophagus:3.66 stomach:- intestine:4.69 colon:4.83     liver/hepato:4.16    lung:3.82 bladder:3.51 kidney:4.36 pituitary:3.74 thyroid/parathyroid:3.74 adrenal gland:- pancreas:4.22 breast:4.27 salivary:3.68
RNA-seq uterus:- placenta:- prostate:3.93 ovary:4.22 testis:4.26 heart:5.19 muscle:5.44 esophagus:- stomach:- intestine:- colon:3.42     liver/hepato:3.89        lung:3.35    bladder:- kidney:4.94 pituitary:- thyroid/parathyroid:5.51 adrenal gland:4.42 pancreas:- breast:4.13 salivary:-

Gene Information

IDs

Refseq ID NM_006796
Gene ID 10939
Unigene ID Hs.528996
Probe set ID 202486_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000141385
GTEx ID ENSG00000141385

Orthologous Gene

Mouse[2]  NM_027130
Rat[1]  NM_001134864

Chromosomal Region

18p11.21  [12,328,943  -  12,377,253]

Gene Family (Interpro ID)

IPR003593  ATPase, AAA+ type, core

Link to Pubmed  (Pubmed ID)

10395799
12477932
14623864
15489334
16169070
16251216
18029348
18769991
18854154
19615732
19748354
20186120
20208537
20301317
20354562
20562859
20725928
20877624
21080425
21139048
21595125
21827917
21832049
21890473
21900206
22022284
22252130
22268729
23000965
23602568
24250222
24457600
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0008219  cell death
GO:0042407  cristae formation
GO:0008053  mitochondrial fusion
GO:0034982  mitochondrial protein processing
GO:0042552  myelination
GO:0021675  nerve development
GO:0007528  neuromuscular junction development
GO:0030163  protein catabolic process
GO:0006508  proteolysis
GO:0040014  regulation of multicellular organism growth
GO:0060013  righting reflex

Cellular Component

GO:0016021  integral to membrane
GO:0005743  mitochondrial inner membrane
GO:0005739  mitochondrion

Molecular Function

GO:0005524  ATP binding
GO:0004222  metalloendopeptidase activity
GO:0017111  nucleoside-triphosphatase activity
GO:0005515  protein binding
GO:0051082  unfolded protein binding
GO:0008270  zinc ion binding