transmembrane emp24 domain trafficking protein 2

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Synonym

FLJ21323, transmembrane emp24 domain trafficking protein 2, TMED2, P24A, RNP24, Membrane protein p24A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:171.80 cerebellum:88.20 brain stem:- corpus callosum/glia:349.90 pineal gland:148.30 peripheral nerve:153.40 spine:112.30 retina:- eye:123.40 artery/aorta:509.60 vein:333.20 lymphnode:101.10 peripheral blood:145.70 spleen:75.60 thymus:154.60 bone marrow:59 adipose:201.70 bone:383.80 skin:249.60
GeneChip cerebrum:8.68 cerebellum:8.63 brain stem:8.84 corpus callosum/glia:8.98 pineal gland:- peripheral nerve:9.30 spine:9.23 retina:- eye:- artery/aorta:9.26 vein:9.65 lymphnode:9.48 peripheral blood:- spleen:9.16 thymus:9.54 bone marrow:9.16 adipose:9.84 bone:- skin:9.72
CAGE cerebrum:4.26 cerebellum:- brain stem:4.31 corpus callosum/glia:4.37 pineal gland:4.45 peripheral nerve:- spine:4.33 retina:- eye:- artery/aorta:4.89 vein:4.30 lymphnode:4.70 peripheral blood:- spleen:4.59 thymus:4.33 bone marrow:- adipose:4.82 bone:- skin:-
RNA-seq cerebrum:6.12 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.67 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.93 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:337.20 placenta:156.70 prostate:315.40 ovary:149.10 testis:129.80 heart:153.30 muscle:120.50 esophagus:342.80 stomach:148.70 intestine:583.20 colon:67.80     liver/hepato:126.70        lung:259    bladder:1507.30 kidney:239.10 pituitary:811.90 thyroid/parathyroid:163.70 adrenal gland:457.10 pancreas:480.10 breast:204.40 salivary:985.20
GeneChip uterus:10.04 placenta:9.74 prostate:10.59 ovary:10.18 testis:9.16 heart:9.52 muscle:9.11 esophagus:9.93 stomach:10.10 intestine:10.17 colon:9.85 liver/hepato:10.05 lung:9.47 bladder:- kidney:9.45 pituitary:9.78 thyroid/parathyroid:10.38 adrenal gland:9.62 pancreas:10.89 breast:10.14 salivary:10.98
CAGE uterus:4.85 placenta:4.93 prostate:4.87 ovary:4.94 testis:4.39 heart:4.80 muscle:4.69 esophagus:4.83 stomach:- intestine:4.82 colon:4.83     liver/hepato:5.98    lung:4.80 bladder:4.87 kidney:4.78 pituitary:4.92 thyroid/parathyroid:5.14 adrenal gland:- pancreas:6.10 breast:4.81 salivary:5.85
RNA-seq uterus:- placenta:- prostate:6.90 ovary:7.48 testis:6.93 heart:5.86 muscle:6.39 esophagus:- stomach:- intestine:- colon:7.05     liver/hepato:7.78        lung:6.94    bladder:- kidney:6.99 pituitary:- thyroid/parathyroid:7.42 adrenal gland:6.56 pancreas:- breast:7.37 salivary:-

Gene Information

IDs

Refseq ID NM_006815
Gene ID 10959
Unigene ID Hs.75914
Probe set ID 200087_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000086598
GTEx ID ENSG00000086598

Orthologous Gene

Mouse[6]  NM_019770
Rat[6]  NM_019770

Chromosomal Region

12q24.31  [124,069,078  -  124,083,116]

Gene Family (Interpro ID)

IPR009038  GOLD

Link to Pubmed  (Pubmed ID)

8663407
8703076
9472029
10214941
10359607
10761932
11703931
11739402
12237308
12477932
15308636
15489334
16641999
17693410
18029348
18187620
18287528
19322201
20360068
20361938
21139048
21219331
21963094
21988832
22212250
22939629
23246001

Gene Ontology  (GO ID)

Biological Process

GO:0048205  COPI coating of Golgi vesicle
GO:0048208  COPII coating of ER-derived vesicle
GO:0048598  embryonic morphogenesis
GO:0006888  ER to Golgi vesicle-mediated transport
GO:0007030  Golgi organization
GO:0006886  intracellular protein transport
GO:0001893  maternal placenta development
GO:0034260  negative regulation of GTPase activity

Cellular Component

GO:0030663  COPI coated vesicle membrane
GO:0030137  COPI-coated vesicle
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005793  ER-Golgi intermediate compartment
GO:0033116  ER-Golgi intermediate compartment membrane
GO:0005794  Golgi apparatus
GO:0032580  Golgi cisterna membrane
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0042589  zymogen granule membrane

Molecular Function

GO:0005515  protein binding