myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11

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Synonym

Protein AF1q, AF1Q, MLLT11, RP11-316M1.10

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:457.50 cerebellum:516.30 brain stem:- corpus callosum/glia:- pineal gland:445 peripheral nerve:306.70 spine:449.20 retina:118.60 eye:94 artery/aorta:89.90 vein:266.60 lymphnode:20.20 peripheral blood:91.10 spleen:- thymus:64.40 bone marrow:39.40 adipose:- bone:- skin:19.20
GeneChip cerebrum:10.38 cerebellum:10.84 brain stem:10.76 corpus callosum/glia:7.71 pineal gland:- peripheral nerve:11.02 spine:9.42 retina:- eye:- artery/aorta:7.23 vein:6.37 lymphnode:5.60 peripheral blood:- spleen:4.91 thymus:8.69 bone marrow:5.09 adipose:5.13 bone:- skin:5.49
CAGE cerebrum:4.99 cerebellum:- brain stem:4.54 corpus callosum/glia:3.49 pineal gland:4.65 peripheral nerve:- spine:3.92 retina:- eye:- artery/aorta:2.64 vein:2.22 lymphnode:1.05 peripheral blood:- spleen:0.84 thymus:4.08 bone marrow:- adipose:0.90 bone:- skin:-
RNA-seq cerebrum:6.48 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.94 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.50 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:- ovary:- testis:13 heart:140.50 muscle:60.30 esophagus:- stomach:- intestine:162 colon:17     liver/hepato:21.10        lung:19.60    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:101.60 pancreas:8.90 breast:- salivary:-
GeneChip uterus:7.01 placenta:4.99 prostate:6.19 ovary:5.85 testis:5.43 heart:7.15 muscle:6.95 esophagus:6.42 stomach:6.13 intestine:6.72 colon:6.79 liver/hepato:5.29 lung:5.29 bladder:- kidney:5.59 pituitary:8.32 thyroid/parathyroid:5.31 adrenal gland:7.33 pancreas:6.34 breast:5.90 salivary:5.57
CAGE uterus:2.29 placenta:1.64 prostate:1.76 ovary:2.30 testis:1.35 heart:3.30 muscle:2.41 esophagus:1.83 stomach:- intestine:2.41 colon:1.98     liver/hepato:0.63    lung:1.12 bladder:2.16 kidney:1.66 pituitary:3.32 thyroid/parathyroid:1.02 adrenal gland:- pancreas:0.58 breast:0.90 salivary:1.00
RNA-seq uterus:- placenta:- prostate:2.25 ovary:2.90 testis:2.15 heart:4.78 muscle:0.75 esophagus:- stomach:- intestine:- colon:2.75     liver/hepato:1.07        lung:1.90    bladder:- kidney:1.76 pituitary:- thyroid/parathyroid:1.78 adrenal gland:1.34 pancreas:- breast:0.75 salivary:-

Gene Information

IDs

Refseq ID NM_006818
Gene ID 10962
Unigene ID Hs.75823
Probe set ID 211071_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000213190
GTEx ID ENSG00000213190

Orthologous Gene

Mouse[2]  NM_019914
Rat[1]  NM_001013912

Chromosomal Region

1q21.3  [151,030,234  -  151,040,970]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7833468
12477932
14702039
15489334
15530661
16710414
17929166
18852119
19396856
20596645
21139048
21145461
21715312
21890473
21906983
22505724
22761939
23000965
24778252

Gene Ontology  (GO ID)

Biological Process

GO:0043065  positive regulation of apoptosis
GO:0051901  positive regulation of mitochondrial depolarization
GO:0090200  positive regulation of release of cytochrome c from mitochondria
GO:0045893  positive regulation of transcription, DNA-dependent

Cellular Component

GO:0005622  intracellular

Molecular Function

GO:0003674  molecular_function