KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

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Synonym

ELP-1, KDEL receptor 2, ERD2-like protein 1, KDELR2, ERD2.2, ER lumen protein retaining receptor 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.49 cerebellum:6.26 brain stem:6.68 corpus callosum/glia:6.93 pineal gland:- peripheral nerve:7.74 spine:7.23 retina:- eye:- artery/aorta:8.03 vein:8.17 lymphnode:8.44 peripheral blood:- spleen:7.98 thymus:7.85 bone marrow:8.48 adipose:8.65 bone:- skin:8.29
CAGE cerebrum:0.38 cerebellum:- brain stem:0.31 corpus callosum/glia:0.55 pineal gland:0.21 peripheral nerve:- spine:0.36 retina:- eye:- artery/aorta:0.79 vein:1.03 lymphnode:1.88 peripheral blood:- spleen:1.46 thymus:1.22 bone marrow:- adipose:2.35 bone:- skin:-
RNA-seq cerebrum:4.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.19 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.18 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.91 placenta:9.92 prostate:9.21 ovary:8.54 testis:10.15 heart:8.60 muscle:7.75 esophagus:8.82 stomach:9.09 intestine:9.32 colon:9.52 liver/hepato:8.79 lung:7.97 bladder:- kidney:8.06 pituitary:8.62 thyroid/parathyroid:8.29 adrenal gland:8.24 pancreas:9.71 breast:8.49 salivary:9.59
CAGE uterus:2.11 placenta:2.10 prostate:1.51 ovary:1.77 testis:1.97 heart:1.19 muscle:0.89 esophagus:2.12 stomach:- intestine:2.76 colon:2.09     liver/hepato:3.41    lung:2.23 bladder:2.03 kidney:1.91 pituitary:0.88 thyroid/parathyroid:1.81 adrenal gland:- pancreas:1.42 breast:2.19 salivary:1.82
RNA-seq uterus:- placenta:- prostate:6.09 ovary:6.74 testis:6.33 heart:4.59 muscle:5.03 esophagus:- stomach:- intestine:- colon:6.02     liver/hepato:7.26        lung:6.31    bladder:- kidney:6.34 pituitary:- thyroid/parathyroid:5.80 adrenal gland:6.13 pancreas:- breast:6.19 salivary:-

Gene Information

IDs

Refseq ID NM_006854
Gene ID 11014
Unigene ID -
Probe set ID 200700_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000136240
GTEx ID ENSG00000136240

Orthologous Gene

Mouse[2]  NM_025841
Rat[1]  NM_001013122

Chromosomal Region

7p22.1  [6,485,584  -  6,523,873]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1316805
1325562
9118249
11752456
12071860
12477932
12690205
12853948
14702039
15489334
16344560
17353931
19322201
21139048
21890473
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0006886  intracellular protein transport
GO:0006621  protein retention in ER lumen
GO:0016192  vesicle-mediated transport

Cellular Component

GO:0005801  cis-Golgi network
GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane

Molecular Function

GO:0005046  KDEL sequence binding