polymerase (DNA directed) sigma

 jump to detail

Synonym

TRF4, Topoisomerase-related function protein 4-1, TRF4-1, POLS, DNA polymerase sigma, POLK, LAK-1, polymerase (DNA directed) sigma

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:36.70 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:94 artery/aorta:- vein:- lymphnode:151.70 peripheral blood:- spleen:37.80 thymus:90.20 bone marrow:39.40 adipose:40.30 bone:38.40 skin:62.40
GeneChip cerebrum:6.89 cerebellum:7.74 brain stem:6.68 corpus callosum/glia:7.05 pineal gland:- peripheral nerve:7.03 spine:6.79 retina:- eye:- artery/aorta:7.62 vein:7.13 lymphnode:7.58 peripheral blood:- spleen:7.66 thymus:8 bone marrow:7.15 adipose:7.59 bone:- skin:7.72
CAGE nodata
RNA-seq cerebrum:1.35 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:51 prostate:67.60 ovary:- testis:47.60 heart:51.10 muscle:- esophagus:- stomach:191.20 intestine:- colon:101.80     liver/hepato:95        lung:73.30    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:111.50 salivary:-
GeneChip uterus:7.70 placenta:7.27 prostate:7.40 ovary:7.62 testis:7.39 heart:6.69 muscle:7.16 esophagus:7.41 stomach:7.33 intestine:7.17 colon:6.88 liver/hepato:7.55 lung:7.69 bladder:- kidney:6.98 pituitary:7.31 thyroid/parathyroid:7.45 adrenal gland:7.28 pancreas:6.32 breast:7.71 salivary:6.55
CAGE nodata
RNA-seq uterus:- placenta:- prostate:2.43 ovary:2.54 testis:2.95 heart:1.73 muscle:0.97 esophagus:- stomach:- intestine:- colon:2.19     liver/hepato:1.11        lung:1.86    bladder:- kidney:1.12 pituitary:- thyroid/parathyroid:2.54 adrenal gland:1.75 pancreas:- breast:2.28 salivary:-

Gene Information

IDs

Refseq ID NM_006999
Gene ID 11044
Unigene ID Hs.481542
Probe set ID 202466_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000112941
GTEx ID ENSG00000112941

Orthologous Gene

Mouse[1]  NM_001169131, NM_198600
Rat[1]  NM_001107333, NM_198600

Chromosomal Region

5p15.31  [6,714,718  -  6,757,161]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10066793
10926539
11459963
12477932
15489334
18330920
18421076
18821564
19240061
19322201
19734545
21878619
22359512
23376078
23548203
23776197
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0051301  cell division
GO:0006260  DNA replication
GO:0006302  double-strand break repair
GO:0007076  mitotic chromosome condensation
GO:0042493  response to drug
GO:0007062  sister chromatid cohesion

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0003887  DNA-directed DNA polymerase activity
GO:0046872  metal ion binding
GO:0043221  SMC protein binding