CHK1 checkpoint homolog (S. pombe)

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Synonym

CHK1, CHEK1, CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:7.10

cerebellum:-

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:149.90

vein:-

lymphnode:50.60

peripheral blood:-

spleen:-

thymus:90.20

bone marrow:-

adipose:-

bone:51.20

skin:28.80

GeneChip

cerebrum:2.86

cerebellum:2.89

brain stem:2.83

corpus callosum/glia:2.78

pineal gland:-

peripheral nerve:2.79

spine:2.78

retina:-

eye:-

artery/aorta:2.88

vein:2.95

lymphnode:3.23

peripheral blood:-

spleen:2.79

thymus:5.33

bone marrow:3.70

adipose:2.89

bone:-

skin:3.01

CAGE

cerebrum:0.61

cerebellum:-

brain stem:0.33

corpus callosum/glia:0.47

pineal gland:0

peripheral nerve:-

spine:0.55

retina:-

eye:-

artery/aorta:0.18

vein:1.29

lymphnode:1.11

peripheral blood:-

spleen:1.41

thymus:3.01

bone marrow:-

adipose:1.29

bone:-

skin:-

RNA-seq

cerebrum:0.01

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.07

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.56

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:18.20

prostate:11.30

ovary:37.30

testis:51.90

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:8.50

liver/hepato:31.70

lung:4.90

bladder:125.60

kidney:-

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.13

placenta:3.10

prostate:2.99

ovary:2.95

testis:3.71

heart:2.74

muscle:2.90

esophagus:3.20

stomach:2.98

intestine:3.09

colon:3.15

liver/hepato:2.75

lung:2.73

bladder:-

kidney:2.77

pituitary:2.83

thyroid/parathyroid:2.79

adrenal gland:2.74

pancreas:3

breast:2.98

salivary:2.91

CAGE

uterus:0.88

placenta:1.39

prostate:1.14

ovary:0.60

testis:1.88

heart:0.51

muscle:0.21

esophagus:1.78

stomach:-

intestine:1.76

colon:1.88

liver/hepato:0.14

lung:0.50

bladder:1.52

kidney:1.38

pituitary:0.26

thyroid/parathyroid:0.17

adrenal gland:-

pancreas:0

breast:0.90

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:0.77

ovary:0.33

testis:1.55

heart:0.19

muscle:0.30

esophagus:-

stomach:-

intestine:-

colon:0.29

liver/hepato:0

lung:0.20

bladder:-

kidney:0.18

pituitary:-

thyroid/parathyroid:0.58

adrenal gland:0.26

pancreas:-

breast:0.66

salivary:-

IDs

Refseq ID	NM_001114121
Gene ID	1111
Unigene ID	Hs.24529
Probe set ID	205393_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000149554
GTEx ID	ENSG00000149554

Orthologous Gene

Mouse[2]	NM_007691
Rat[1]	NM_080400

Chromosomal Region

11q24.2 [125,495,036 - 125,546,150]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0071313	cellular response to caffeine
GO:0071260	cellular response to mechanical stimulus
GO:0048096	chromatin-mediated maintenance of transcription
GO:0000077	DNA damage checkpoint
GO:0006975	DNA damage induced protein phosphorylation
GO:0006281	DNA repair
GO:0006260	DNA replication
GO:0031572	G2/M transition DNA damage checkpoint
GO:0000086	G2/M transition of mitotic cell cycle
GO:0045839	negative regulation of mitosis
GO:0018107	peptidyl-threonine phosphorylation
GO:0042127	regulation of cell proliferation
GO:0010569	regulation of double-strand break repair via homologous recombination
GO:0046602	regulation of mitotic centrosome separation
GO:0033261	regulation of S phase
GO:0010767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage
GO:0006974	response to DNA damage stimulus

Cellular Component

GO:0005813	centrosome
GO:0000785	chromatin
GO:0000781	chromosome, telomeric region
GO:0000794	condensed nuclear chromosome
GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005657	replication fork

Molecular Function

GO:0005524	ATP binding
GO:0005515	protein binding
GO:0004674	protein serine/threonine kinase activity

CHK1 checkpoint homolog (S. pombe)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function