chimerin (chimaerin) 1

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Synonym

ARHGAP2, A-chimaerin, chimerin (chimaerin) 1, RHOGAP2, N-chimerin, NC, Alpha chimerin, n-chimerin, CHN, CHN1, N-chimaerin, Rho-GTPase-activating protein 2, RhoGAP2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:10.94 cerebellum:9.40 brain stem:9.98 corpus callosum/glia:8.17 pineal gland:- peripheral nerve:8.03 spine:8.40 retina:- eye:- artery/aorta:6.91 vein:6.80 lymphnode:7.27 peripheral blood:- spleen:6.06 thymus:4.84 bone marrow:5.23 adipose:6.64 bone:- skin:5.84
CAGE cerebrum:5.99 cerebellum:- brain stem:4.66 corpus callosum/glia:4.25 pineal gland:3.10 peripheral nerve:- spine:3.71 retina:- eye:- artery/aorta:2.79 vein:2.62 lymphnode:2.82 peripheral blood:- spleen:2.15 thymus:0.99 bone marrow:- adipose:2.66 bone:- skin:-
RNA-seq cerebrum:3.47 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.63 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.80 placenta:7.20 prostate:6.74 ovary:6.25 testis:7.73 heart:6.52 muscle:5.51 esophagus:6.01 stomach:6.51 intestine:6.33 colon:5.97 liver/hepato:5.30 lung:7.61 bladder:- kidney:5.72 pituitary:8.69 thyroid/parathyroid:6.16 adrenal gland:6.72 pancreas:5.80 breast:6.84 salivary:5.37
CAGE uterus:2.73 placenta:3.02 prostate:3.24 ovary:2.43 testis:3.14 heart:2.77 muscle:1.27 esophagus:2.66 stomach:- intestine:1.74 colon:2.08     liver/hepato:0.63    lung:3.29 bladder:2.45 kidney:1.63 pituitary:4.26 thyroid/parathyroid:2.06 adrenal gland:- pancreas:0.58 breast:2.87 salivary:1.49
RNA-seq uterus:- placenta:- prostate:1.19 ovary:2.08 testis:3.59 heart:1.80 muscle:0.31 esophagus:- stomach:- intestine:- colon:1.48     liver/hepato:0.00        lung:1.86    bladder:- kidney:0.89 pituitary:- thyroid/parathyroid:2.18 adrenal gland:2.34 pancreas:- breast:1.60 salivary:-

Gene Information

IDs

Refseq ID NM_001822
Gene ID 1123
Unigene ID -
Probe set ID 212624_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000128656
GTEx ID ENSG00000128656

Orthologous Gene

Mouse[4]  NM_001113246, NM_001166603, NM_029716, NM_175752
Rat[4]  NM_001113246, NM_001166603, NM_029716, NM_175752

Chromosomal Region

2q31.1  [175,664,091  -  175,870,097]

Gene Family (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

1445199
2268301
2299665
7867622
8336731
8496137
10577917
11438594
12477932
14702039
15013773
15489334
15761153
15815621
16169070
16221859
16273093
16344560
17197532
17197533
18249095
18653847
18826946
19541263
20034095
20301369
20379614
20468071
20535495
21555619
21715346
21715684
21900206
23284715
24338392

Gene Ontology  (GO ID)

Biological Process

GO:0048013  ephrin receptor signaling pathway
GO:0008045  motor axon guidance
GO:0050770  regulation of axonogenesis
GO:0032314  regulation of Rac GTPase activity
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005829  cytosol

Molecular Function

GO:0046875  ephrin receptor binding
GO:0005096  GTPase activator activity
GO:0046872  metal ion binding
GO:0005070  SH3/SH2 adaptor activity