egl nine homolog 2 (C. elegans)

Synonym

PHD1, EGL nine (C.elegans) homolog 2, DKFZp434E026, HIFPH1, HIF-PH1, EGLN2, Prolyl hydroxylase domain-containing protein 1, Estrogen-induced tag 6, HPH-3, egl nine homolog 2 (C. elegans), HIF-prolyl hydroxylase 1, Hypoxia-inducible factor prolyl hydroxylase 1, EIT6, Egl nine homolog 2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:188.40

cerebellum:491.20

brain stem:-

corpus callosum/glia:320.80

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:99.90

artery/aorta:149.90

vein:133.30

lymphnode:394.30

peripheral blood:164

spleen:869.70

thymus:360.70

bone marrow:19.70

adipose:161.30

bone:166.30

skin:100.80

GeneChip

cerebrum:7.84

cerebellum:7.96

brain stem:7.75

corpus callosum/glia:7.93

pineal gland:-

peripheral nerve:8.11

spine:7.54

retina:-

eye:-

artery/aorta:8

vein:8.02

lymphnode:8.31

peripheral blood:-

spleen:8.79

thymus:7.64

bone marrow:7.96

adipose:8.07

bone:-

skin:7.49

CAGE

cerebrum:3.41

cerebellum:-

brain stem:3.32

corpus callosum/glia:3.47

pineal gland:2.72

peripheral nerve:-

spine:3.05

retina:-

eye:-

artery/aorta:3.65

vein:3.67

lymphnode:3.40

peripheral blood:-

spleen:3.50

thymus:2.86

bone marrow:-

adipose:3.19

bone:-

skin:-

RNA-seq

cerebrum:3.01

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.72

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.06

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:264.30

placenta:214.90

prostate:259.10

ovary:186.30

testis:389.40

heart:140.50

muscle:40.20

esophagus:342.80

stomach:127.50

intestine:615.60

colon:203.50

liver/hepato:63.30

lung:244.40

bladder:376.80

kidney:104

pituitary:116

thyroid/parathyroid:1473.70

adrenal gland:660.20

pancreas:35.60

breast:204.40

salivary:-

GeneChip

uterus:7.74

placenta:8.53

prostate:7.30

ovary:7.87

testis:9.50

heart:7.75

muscle:7.17

esophagus:7.79

stomach:7.80

intestine:7.65

colon:7.90

liver/hepato:7.89

lung:8.61

bladder:-

kidney:7.66

pituitary:7.80

thyroid/parathyroid:8.05

adrenal gland:8.02

pancreas:7.51

breast:7.98

salivary:7.76

CAGE

uterus:3.57

placenta:3.99

prostate:3.46

ovary:3.34

testis:4.32

heart:3.32

muscle:2.87

esophagus:3.08

stomach:-

intestine:3.00

colon:3.61

liver/hepato:3.07

lung:3.86

bladder:3.36

kidney:2.91

pituitary:2.95

thyroid/parathyroid:3.65

adrenal gland:-

pancreas:3.06

breast:3.89

salivary:3.15

RNA-seq

uterus:-

placenta:-

prostate:4.66

ovary:4.41

testis:5.04

heart:2.94

muscle:3.11

esophagus:-

stomach:-

intestine:-

colon:4.15

liver/hepato:3.45

lung:4.81

bladder:-

kidney:4.02

pituitary:-

thyroid/parathyroid:4.20

adrenal gland:4.33

pancreas:-

breast:4.23

salivary:-

IDs

Refseq ID	NM_080732
Gene ID	112398
Unigene ID	Hs.515417
Probe set ID	220956_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000171570
GTEx ID	ENSG00000171570

Orthologous Gene

Mouse[1]	NM_053208
Rat[1]	NM_001004083

Chromosomal Region

19q13.2 [41,305,048 - 41,314,336]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR005123	Oxoglutarate/iron-dependent oxygenase
IPR006620	Prolyl 4-hydroxylase, alpha subunit

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0045454	cell redox homeostasis
GO:0071456	cellular response to hypoxia
GO:0030520	estrogen receptor signaling pathway
GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0045732	positive regulation of protein catabolic process
GO:0001558	regulation of cell growth
GO:0043523	regulation of neuron apoptosis
GO:0001666	response to hypoxia

Cellular Component

GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0008198	ferrous iron binding
GO:0031418	L-ascorbic acid binding
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0019826	oxygen sensor activity
GO:0031545	peptidyl-proline 4-dioxygenase activity
GO:0005515	protein binding

egl nine homolog 2 (C. elegans)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function