kelch-like 2, Mayven (Drosophila)

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Synonym

Kelch-like protein 2, Actin-binding protein Mayven, kelch-like 2, Mayven (Drosophila), ABP-KELCH, MAYVEN, kelch (Drosophila)-like 2 (Mayven), KLHL2, MAV

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:53.30 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:- spine:- retina:237.30 eye:47 artery/aorta:30 vein:- lymphnode:30.30 peripheral blood:18.20 spleen:- thymus:25.80 bone marrow:59 adipose:- bone:12.80 skin:28.80
GeneChip cerebrum:8.70 cerebellum:6.85 brain stem:8.07 corpus callosum/glia:8.77 pineal gland:- peripheral nerve:6.83 spine:8.12 retina:- eye:- artery/aorta:6.15 vein:6.42 lymphnode:6.49 peripheral blood:- spleen:6.91 thymus:5.76 bone marrow:6.91 adipose:5.97 bone:- skin:6.59
CAGE cerebrum:4.07 cerebellum:- brain stem:3.89 corpus callosum/glia:4.13 pineal gland:3.04 peripheral nerve:- spine:3.89 retina:- eye:- artery/aorta:3.17 vein:2.89 lymphnode:3.20 peripheral blood:- spleen:3.57 thymus:1.90 bone marrow:- adipose:3.01 bone:- skin:-
RNA-seq cerebrum:3.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.81 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.35 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:10.90 prostate:- ovary:37.30 testis:43.30 heart:12.80 muscle:- esophagus:- stomach:42.50 intestine:32.40 colon:25.40     liver/hepato:31.70        lung:19.60    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:27.90 salivary:-
GeneChip uterus:6.45 placenta:5.92 prostate:6.98 ovary:6.36 testis:5.71 heart:5.97 muscle:5.03 esophagus:6.83 stomach:6.31 intestine:5.82 colon:5.32 liver/hepato:7.61 lung:7.07 bladder:- kidney:6.77 pituitary:7.60 thyroid/parathyroid:7.03 adrenal gland:6.91 pancreas:5.59 breast:6.72 salivary:7.83
CAGE uterus:2.63 placenta:2.39 prostate:2.47 ovary:2.40 testis:2.37 heart:2.94 muscle:1.81 esophagus:3.17 stomach:- intestine:2.41 colon:2.52     liver/hepato:3.18    lung:3.56 bladder:2.58 kidney:3.21 pituitary:3.85 thyroid/parathyroid:2.88 adrenal gland:- pancreas:2.90 breast:3.27 salivary:3.54
RNA-seq uterus:- placenta:- prostate:2.77 ovary:1.26 testis:2.05 heart:1.96 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.96     liver/hepato:2.73        lung:2.61    bladder:- kidney:2.54 pituitary:- thyroid/parathyroid:2.37 adrenal gland:2.53 pancreas:- breast:0.88 salivary:-

Gene Information

IDs

Refseq ID NM_001161521
Gene ID 11275
Unigene ID Hs.388668
Probe set ID 219157_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000109466
GTEx ID ENSG00000109466

Orthologous Gene

Mouse[1]  NM_178633
Rat[1]  NM_178633

Chromosomal Region

4q32.3  [166,128,770  -  166,244,308]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like

Link to Pubmed  (Pubmed ID)

10397770
12477932
15383316
15489334
15735724
16035103
16189514
16344560
19121354
20360068
20379614
21145461
21549840
23676014
23838290
24641320

Gene Ontology  (GO ID)

Biological Process

GO:0016567  protein ubiquitination

Cellular Component

GO:0015629  actin cytoskeleton
GO:0031463  Cul3-RING ubiquitin ligase complex
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0030027  lamellipodium
GO:0001726  ruffle

Molecular Function

GO:0003779  actin binding
GO:0005515  protein binding