cholinergic receptor, nicotinic, alpha 3

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Synonym

MGC104879, CHRNA3, cholinergic receptor, nicotinic, alpha 3, NACHRA3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.60

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:673.80

retina:118.60

eye:117.50

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:116

bone marrow:-

adipose:-

bone:12.80

skin:4.80

GeneChip

cerebrum:6.08

cerebellum:6.43

brain stem:5.96

corpus callosum/glia:6.01

pineal gland:-

peripheral nerve:6.25

spine:6.08

retina:-

eye:-

artery/aorta:6.17

vein:6.15

lymphnode:6.14

peripheral blood:-

spleen:5.98

thymus:8.33

bone marrow:6.24

adipose:6.27

bone:-

skin:6.16

CAGE

cerebrum:1.07

cerebellum:-

brain stem:0.37

corpus callosum/glia:0.94

pineal gland:4.83

peripheral nerve:-

spine:0.29

retina:-

eye:-

artery/aorta:0.69

vein:2.67

lymphnode:1.08

peripheral blood:-

spleen:0.32

thymus:4.62

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.26

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.35

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:37.30

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:85

intestine:-

colon:8.50

liver/hepato:-

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:6

placenta:5.93

prostate:6.11

ovary:5.88

testis:6.10

heart:5.92

muscle:6.11

esophagus:6.08

stomach:6.04

intestine:6.23

colon:6.39

liver/hepato:5.94

lung:5.97

bladder:-

kidney:5.95

pituitary:6.13

thyroid/parathyroid:6

adrenal gland:6.25

pancreas:6.47

breast:5.94

salivary:6.06

CAGE

uterus:0.32

placenta:0.08

prostate:0.91

ovary:0

testis:0.67

heart:1.08

muscle:0

esophagus:0.82

stomach:-

intestine:1.43

colon:2.28

liver/hepato:0

lung:0

bladder:0.98

kidney:0

pituitary:1.46

thyroid/parathyroid:0.32

adrenal gland:-

pancreas:0

breast:0.55

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:1.56

ovary:0.12

testis:1.02

heart:0.15

muscle:0

esophagus:-

stomach:-

intestine:-

colon:2.53

liver/hepato:0

lung:0.07

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.19

adrenal gland:1.67

pancreas:-

breast:0.01

salivary:-

IDs

Refseq ID	NM_000743
Gene ID	1136
Unigene ID	Hs.89605
Probe set ID	211587_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000080644
GTEx ID	ENSG00000080644

Orthologous Gene

Mouse[2]	NM_145129
Rat[1]	NM_052805

Chromosomal Region

15q25.1 [78,885,394 - 78,913,637]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006201

Neurotransmitter-gated ion-channel

Gene Ontology (GO ID)

Biological Process

GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity
GO:0035095	behavioral response to nicotine
GO:0006811	ion transport
GO:0007626	locomotory behavior
GO:0007399	nervous system development
GO:0014056	regulation of acetylcholine secretion
GO:0048814	regulation of dendrite morphogenesis
GO:0060079	regulation of excitatory postsynaptic membrane potential
GO:0042391	regulation of membrane potential
GO:0006940	regulation of smooth muscle contraction
GO:0007165	signal transduction
GO:0007268	synaptic transmission
GO:0060084	synaptic transmission involved in micturition
GO:0007271	synaptic transmission, cholinergic

Cellular Component

GO:0030054	cell junction
GO:0043025	cell soma
GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex
GO:0005886	plasma membrane
GO:0014069	postsynaptic density
GO:0045211	postsynaptic membrane

Molecular Function

GO:0042166	acetylcholine binding
GO:0015464	acetylcholine receptor activity
GO:0015276	ligand-gated ion channel activity
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity

cholinergic receptor, nicotinic, alpha 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function