cholinergic receptor, nicotinic, alpha 7

Synonym

nAChR a7, CHRNA7, nAChR alpha7, cholinergic receptor, nicotinic, alpha 7, nAChR alpha 7, neuronal nicotinic acetylcholine receptor subunit, alpha7, NACHRA7

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:9.50

cerebellum:12.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:336.90

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:14.40

GeneChip

cerebrum:4.75

cerebellum:4.27

brain stem:4.84

corpus callosum/glia:4.34

pineal gland:-

peripheral nerve:5.82

spine:4.50

retina:-

eye:-

artery/aorta:4.69

vein:4.59

lymphnode:4.72

peripheral blood:-

spleen:4.55

thymus:4.15

bone marrow:4.64

adipose:4.37

bone:-

skin:4.44

CAGE

nodata

RNA-seq

cerebrum:0.35

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.53

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:11.30

ovary:-

testis:13

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:32.40

colon:-

liver/hepato:-

lung:9.80

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:-

salivary:-

GeneChip

uterus:4.47

placenta:4.06

prostate:4.92

ovary:4.33

testis:5.75

heart:4.59

muscle:4.66

esophagus:4.63

stomach:4.70

intestine:4.67

colon:4.55

liver/hepato:4.30

lung:4.48

bladder:-

kidney:4.32

pituitary:4.54

thyroid/parathyroid:5.21

adrenal gland:4.52

pancreas:4.68

breast:4.23

salivary:4.70

CAGE

nodata

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.56

testis:1.08

heart:0.16

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.25

liver/hepato:0.00

lung:0.75

bladder:-

kidney:0.19

pituitary:-

thyroid/parathyroid:1.10

adrenal gland:0.59

pancreas:-

breast:0.07

salivary:-

IDs

Refseq ID	NM_000746
Gene ID	1139
Unigene ID	Hs.511772
Probe set ID	210123_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000175344
GTEx ID	ENSG00000175344

Orthologous Gene

Mouse[1]	NM_007390
Rat [0]

Chromosomal Region

15q13.2 [30,875,128 - 32,464,722]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006201

Neurotransmitter-gated ion-channel

Gene Ontology (GO ID)

Biological Process

GO:0000187	activation of MAPK activity
GO:0006816	calcium ion transport
GO:0006874	cellular calcium ion homeostasis
GO:0050890	cognition
GO:0006811	ion transport
GO:0007613	memory
GO:0032720	negative regulation of tumor necrosis factor production
GO:0045766	positive regulation of angiogenesis
GO:0008284	positive regulation of cell proliferation
GO:0001666	response to hypoxia
GO:0035094	response to nicotine
GO:0007165	signal transduction
GO:0007268	synaptic transmission

Cellular Component

GO:0030054	cell junction
GO:0016021	integral to membrane
GO:0005892	nicotinic acetylcholine-gated receptor-channel complex
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane

Molecular Function

GO:0042166	acetylcholine binding
GO:0015464	acetylcholine receptor activity
GO:0001540	beta-amyloid binding
GO:0017081	chloride channel regulator activity
GO:0004889	nicotinic acetylcholine-activated cation-selective channel activity
GO:0042803	protein homodimerization activity
GO:0015643	toxin binding

cholinergic receptor, nicotinic, alpha 7

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function