cold inducible RNA binding protein

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Synonym

cold inducible RNA-binding protein, CIRBP, A18HNRNP, Glycine-rich RNA-binding protein CIRP, A18 hnRNP, Cold-inducible RNA-binding protein, cold inducible RNA binding protein, CIRP

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:15.40 cerebellum:63 brain stem:- corpus callosum/glia:58.30 pineal gland:148.30 peripheral nerve:122.70 spine:- retina:- eye:52.90 artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:9.38 cerebellum:10.20 brain stem:9.44 corpus callosum/glia:9.50 pineal gland:- peripheral nerve:8.78 spine:9.49 retina:- eye:- artery/aorta:8.97 vein:9.14 lymphnode:9.36 peripheral blood:- spleen:9.01 thymus:9.14 bone marrow:7.99 adipose:9.40 bone:- skin:9.86
CAGE cerebrum:5.74 cerebellum:- brain stem:5.50 corpus callosum/glia:6.20 pineal gland:5.63 peripheral nerve:- spine:5.31 retina:- eye:- artery/aorta:6.05 vein:5.92 lymphnode:5.69 peripheral blood:- spleen:5.12 thymus:4.93 bone marrow:- adipose:5.07 bone:- skin:-
RNA-seq cerebrum:7.98 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.98 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.77 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:3.60 prostate:22.50 ovary:- testis:8.70 heart:51.10 muscle:40.20 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:39.10    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:9.30 salivary:-
GeneChip uterus:9.56 placenta:9.12 prostate:10.30 ovary:10.25 testis:9.79 heart:8.61 muscle:9.63 esophagus:9 stomach:8.77 intestine:8.97 colon:8.73 liver/hepato:7.76 lung:8.73 bladder:- kidney:9.50 pituitary:10.99 thyroid/parathyroid:10.59 adrenal gland:9.33 pancreas:10.01 breast:10.11 salivary:9.71
CAGE uterus:6.06 placenta:5.39 prostate:5.59 ovary:5.93 testis:5.76 heart:5.42 muscle:5.97 esophagus:5.02 stomach:- intestine:5.30 colon:5.42     liver/hepato:4.88    lung:5.45 bladder:5.67 kidney:5.08 pituitary:6.01 thyroid/parathyroid:5.58 adrenal gland:- pancreas:6.23 breast:4.75 salivary:6.23
RNA-seq uterus:- placenta:- prostate:7.38 ovary:7.69 testis:6.82 heart:6.03 muscle:6.34 esophagus:- stomach:- intestine:- colon:6.54     liver/hepato:5.17        lung:6.02    bladder:- kidney:5.83 pituitary:- thyroid/parathyroid:8.42 adrenal gland:8.26 pancreas:- breast:7.51 salivary:-

Gene Information

IDs

Refseq ID NM_001280
Gene ID 1153
Unigene ID Hs.634522
Probe set ID 200810_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000099622
GTEx ID ENSG00000099622

Orthologous Gene

Mouse[1]  NM_007705
Rat [0]  

Chromosomal Region

19p13.3  [1,269,267  -  1,274,806]

Gene Family (Interpro ID)

IPR000504  RNA recognition motif, RNP-1
IPR003954  RNA recognition, domain 1

Link to Pubmed  (Pubmed ID)

9151692
9334257
9422546
9434172
11574538
11850402
12477932
12819390
14702039
15057824
15075239
15342556
15489334
16189514
16513844
16713569
17332742
17353931
18482256
19158277
19277990
19322201
19738201
21139048
21145461
21832049
21906983
21988832
22113938
22365833
22939629
22990118
23151878
23184937
23437386
23874603
24097189
24244333
24250222
24457600
24583282

Gene Ontology  (GO ID)

Biological Process

GO:0048255  mRNA stabilization
GO:0045727  positive regulation of translation
GO:0009409  response to cold
GO:0009411  response to UV
GO:0034063  stress granule assembly

Cellular Component

GO:0005737  cytoplasm
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0010494  stress granule

Molecular Function

GO:0003730  mRNA 3'-UTR binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0070181  SSU rRNA binding
GO:0030371  translation repressor activity