adducin 1 (alpha)

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Synonym

ADDA, ADD1, Erythrocyte adducin subunit alpha, adducin 1 (alpha), MGC3339, MGC44427, Alpha-adducin

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:184.90

cerebellum:50.40

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:153.40

spine:786.10

retina:118.60

eye:528.90

artery/aorta:-

vein:-

lymphnode:273

peripheral blood:54.70

spleen:94.50

thymus:77.30

bone marrow:216.50

adipose:242

bone:166.30

skin:139.20

GeneChip

cerebrum:8.74

cerebellum:8.78

brain stem:8.68

corpus callosum/glia:8.58

pineal gland:-

peripheral nerve:8.84

spine:8.46

retina:-

eye:-

artery/aorta:8.76

vein:8.49

lymphnode:8.21

peripheral blood:-

spleen:8.52

thymus:8.07

bone marrow:8.03

adipose:8.35

bone:-

skin:8.27

CAGE

cerebrum:4.82

cerebellum:-

brain stem:4.81

corpus callosum/glia:4.90

pineal gland:4.32

peripheral nerve:-

spine:4.50

retina:-

eye:-

artery/aorta:4.71

vein:4.15

lymphnode:4.15

peripheral blood:-

spleen:4.22

thymus:3.92

bone marrow:-

adipose:4.15

bone:-

skin:-

RNA-seq

cerebrum:4.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.63

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:5.75

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:164

placenta:83.80

prostate:67.60

ovary:745.30

testis:225

heart:204.30

muscle:80.40

esophagus:-

stomach:85

intestine:-

colon:118.70

liver/hepato:116.10

lung:88

bladder:-

kidney:83.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:53.30

breast:213.70

salivary:-

GeneChip

uterus:8.58

placenta:7.43

prostate:8.59

ovary:8.73

testis:8.27

heart:7.99

muscle:8.25

esophagus:8.35

stomach:8.07

intestine:7.86

colon:8.25

liver/hepato:7.42

lung:8.60

bladder:-

kidney:8.17

pituitary:8.16

thyroid/parathyroid:8.37

adrenal gland:8.02

pancreas:6.99

breast:8.62

salivary:7.66

CAGE

uterus:4.43

placenta:4.02

prostate:4.42

ovary:4.55

testis:4.22

heart:4.34

muscle:4.38

esophagus:4.29

stomach:-

intestine:4.32

colon:4.32

liver/hepato:3.78

lung:4.31

bladder:4.40

kidney:4.25

pituitary:4.08

thyroid/parathyroid:4.02

adrenal gland:-

pancreas:4.02

breast:4.49

salivary:4.03

RNA-seq

uterus:-

placenta:-

prostate:6.30

ovary:6.03

testis:5.35

heart:4.74

muscle:5.63

esophagus:-

stomach:-

intestine:-

colon:5.70

liver/hepato:4.23

lung:5.46

bladder:-

kidney:5.25

pituitary:-

thyroid/parathyroid:5.11

adrenal gland:5.50

pancreas:-

breast:5.22

salivary:-

IDs

Refseq ID	NM_001119
Gene ID	118
Unigene ID	Hs.183706
Probe set ID	214736_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000087274
GTEx ID	ENSG00000087274

Orthologous Gene

Mouse[9]	NM_001024458, NM_001102444, NM_013457
Rat [0]

Chromosomal Region

4p16.3 [2,845,584 - 2,931,803]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0030036	actin cytoskeleton organization
GO:0051017	actin filament bundle formation
GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0006915	apoptosis
GO:0051016	barbed-end actin filament capping
GO:0000902	cell morphogenesis
GO:0006921	cell structure disassembly during apoptosis
GO:0006884	cell volume homeostasis
GO:0044267	cellular protein metabolic process
GO:0071300	cellular response to retinoic acid
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0030218	erythrocyte differentiation
GO:0020027	hemoglobin metabolic process
GO:0048873	homeostasis of number of cells within a tissue
GO:0001701	in utero embryonic development
GO:0035264	multicellular organism growth
GO:0045766	positive regulation of angiogenesis
GO:0045807	positive regulation of endocytosis
GO:0032092	positive regulation of protein binding

Cellular Component

GO:0005829	cytosol
GO:0043197	dendritic spine
GO:0008290	F-actin capping protein complex
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0014069	postsynaptic density

Molecular Function

GO:0003779	actin binding
GO:0051015	actin filament binding
GO:0005516	calmodulin binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity
GO:0030507	spectrin binding
GO:0005198	structural molecule activity
GO:0042608	T cell receptor binding
GO:0008134	transcription factor binding

adducin 1 (alpha)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function