chloride intracellular channel 1

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Synonym

NCC27, chloride intracellular channel 1, Regulatory nuclear chloride ion channel protein, CLIC1, Nuclear chloride ion channel 27, Chloride channel ABP, p64CLCP, Chloride intracellular channel protein 1, hRNCC, G6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:41.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:153.40 spine:- retina:118.60 eye:152.80 artery/aorta:599.50 vein:199.90 lymphnode:151.70 peripheral blood:783.40 spleen:75.60 thymus:51.50 bone marrow:236.20 adipose:121 bone:51.20 skin:360
GeneChip cerebrum:6.31 cerebellum:6.15 brain stem:6.60 corpus callosum/glia:7.14 pineal gland:- peripheral nerve:8.86 spine:7.67 retina:- eye:- artery/aorta:9.27 vein:9.55 lymphnode:9.40 peripheral blood:- spleen:9.55 thymus:9.17 bone marrow:9.61 adipose:9.32 bone:- skin:9.59
CAGE cerebrum:3.12 cerebellum:- brain stem:3.72 corpus callosum/glia:3.63 pineal gland:3.62 peripheral nerve:- spine:4.01 retina:- eye:- artery/aorta:5.19 vein:5.42 lymphnode:5.44 peripheral blood:- spleen:5.73 thymus:5.16 bone marrow:- adipose:5.55 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:247.70 prostate:270.30 ovary:74.50 testis:64.90 heart:332.10 muscle:- esophagus:- stomach:446.10 intestine:194.40 colon:288.30     liver/hepato:116.10        lung:361.70    bladder:- kidney:62.40 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:337.90 breast:120.80 salivary:-
GeneChip uterus:9.30 placenta:9.17 prostate:9.70 ovary:9.50 testis:7.43 heart:8.56 muscle:6.73 esophagus:9.98 stomach:9.24 intestine:9.07 colon:9.76 liver/hepato:7.78 lung:9.96 bladder:- kidney:8.98 pituitary:8.01 thyroid/parathyroid:9.18 adrenal gland:8.48 pancreas:8.53 breast:9.68 salivary:8.76
CAGE uterus:5.00 placenta:5.60 prostate:5.20 ovary:4.96 testis:4.16 heart:4.80 muscle:3.62 esophagus:5.49 stomach:- intestine:5.37 colon:5.30     liver/hepato:4.54    lung:5.44 bladder:5.29 kidney:5.60 pituitary:4.03 thyroid/parathyroid:5.15 adrenal gland:- pancreas:4.73 breast:5.13 salivary:4.89
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_001288
Gene ID 1192
Unigene ID Hs.414565
Probe set ID 208659_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000206394
ENSG00000213719
ENSG00000223639
ENSG00000226248
ENSG00000226417
ENSG00000226651
GTEx ID ENSG00000206394
ENSG00000213719
ENSG00000223639
ENSG00000226248
ENSG00000226417
ENSG00000226651

Orthologous Gene

Mouse[1]  NM_033444
Rat[1]  NM_001002807

Chromosomal Region

HSCHR6_MHC_QBL  [31,688,591  -  31,697,781]
HSCHR6_MHC_COX  [31,685,771  -  31,694,945]
HSCHR6_MHC_MANN  [31,737,851  -  31,747,033]
HSCHR6_MHC_SSTO  [31,688,317  -  31,697,500]
6p21.33  [31,698,358  -  31,707,540]
HSCHR6_MHC_MCF  [31,774,644  -  31,783,827]
HSCHR6_MHC_DBB  [31,680,530  -  31,689,717]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1345164
7711732
7938007
8125298
9139710
9339381
9841507
10191309
10384126
10793131
10834939
11195932
11551966
11978800
12163479
12477932
12681486
14574404
14613939
14656967
14667819
15190104
15326289
15489334
15827065
16009940
16130169
16236267
16289162
16712791
17326840
17347778
17620599
18028448
18710659
18850721
19143814
19143821
19299076
19659809
19703605
19738201
19845400
19851445
19913121
19946888
20461716
20507120
20587610
20628086
21139048
21319273
21858536
21890473
21906983
21963094
21988832
22082111
22173998
22242893
22268729
22304920
22426742
22505724
22578365
22623428
22791942
22952844
23000965
23166591
23457643
23593969
23792823
24058583
24089665
24115360
24328417
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006821  chloride transport
GO:0045669  positive regulation of osteoblast differentiation
GO:0051881  regulation of mitochondrial membrane potential
GO:0007165  signal transduction

Cellular Component

GO:0005903  brush border
GO:0034707  chloride channel complex
GO:0005737  cytoplasm
GO:0005739  mitochondrion
GO:0005635  nuclear envelope
GO:0031965  nuclear membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0005254  chloride channel activity
GO:0005515  protein binding
GO:0005247  voltage-gated chloride channel activity