tryptophan hydroxylase 2

Synonym

Tryptophan 5-hydroxylase 2, tryptophan hydroxylase 2, Tryptophan 5-monooxygenase 2, FLJ37295, MGC138871, MGC138872, NTPH, Neuronal tryptophan hydroxylase, TPH2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:3.60

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

nodata

CAGE

cerebrum:0.35

cerebellum:-

brain stem:1.72

corpus callosum/glia:0.07

pineal gland:0

peripheral nerve:-

spine:0.32

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.42

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

nodata

CAGE

uterus:0.04

placenta:0

prostate:0

ovary:0

testis:0

heart:0

muscle:0

esophagus:0

stomach:-

intestine:0

colon:0.04

liver/hepato:0

lung:0

bladder:0

kidney:0

pituitary:1.62

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0

ovary:0

testis:0.09

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.01

adrenal gland:0

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_173353
Gene ID	121278
Unigene ID	Hs.376337
Probe set ID	-
Ensembl ID	ENSG00000139287
GTEx ID	ENSG00000139287

Orthologous Gene

Mouse[1]	NM_173391
Rat[1]	NM_173839

Chromosomal Region

12q21.1 [72,332,626 - 72,580,398]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001273	Aromatic amino acid hydroxylase
IPR005963	Tryptophan 5-monooxygenase
IPR019773	Tyrosine 3-monooxygenase-like

GO:0009072	aromatic amino acid family metabolic process
GO:0034641	cellular nitrogen compound metabolic process
GO:0071285	cellular response to lithium ion
GO:0007623	circadian rhythm
GO:0046219	indolalkylamine biosynthetic process
GO:0014823	response to activity
GO:0051592	response to calcium ion
GO:0043627	response to estrogen stimulus
GO:0051384	response to glucocorticoid stimulus
GO:0031667	response to nutrient levels
GO:0006950	response to stress
GO:0042427	serotonin biosynthetic process

GO:0005829	cytosol
GO:0043005	neuron projection

GO:0016597	amino acid binding
GO:0005506	iron ion binding
GO:0004510	tryptophan 5-monooxygenase activity

tryptophan hydroxylase 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function