tetratricopeptide repeat domain 8

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Synonym

tetratricopeptide repeat domain 8, TTC8, TPR repeat protein 8, Tetratricopeptide repeat protein 8, Bardet-Biedl syndrome 8 protein, BBS8

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:34.40 cerebellum:25.20 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:- spine:112.30 retina:355.90 eye:76.40 artery/aorta:60 vein:- lymphnode:10.10 peripheral blood:18.20 spleen:- thymus:25.80 bone marrow:- adipose:- bone:- skin:52.80
GeneChip nodata
CAGE cerebrum:3.42 cerebellum:- brain stem:2.90 corpus callosum/glia:3.11 pineal gland:4.26 peripheral nerve:- spine:3.03 retina:- eye:- artery/aorta:3.44 vein:2.71 lymphnode:2.35 peripheral blood:- spleen:2.52 thymus:1.62 bone marrow:- adipose:2.51 bone:- skin:-
RNA-seq cerebrum:0.05 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:36.40 prostate:101.40 ovary:- testis:64.90 heart:- muscle:- esophagus:- stomach:21.20 intestine:- colon:17     liver/hepato:-        lung:34.20    bladder:- kidney:20.80 pituitary:232 thyroid/parathyroid:- adrenal gland:203.10 pancreas:124.50 breast:18.60 salivary:-
GeneChip nodata
CAGE uterus:3.54 placenta:2.58 prostate:3.41 ovary:4.03 testis:4.34 heart:2.64 muscle:1.30 esophagus:2.93 stomach:- intestine:2.31 colon:2.84     liver/hepato:3.26    lung:2.79 bladder:3.10 kidney:3.21 pituitary:4.87 thyroid/parathyroid:3.81 adrenal gland:- pancreas:2.86 breast:2.74 salivary:3.38
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.25        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.09 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_144596
Gene ID 123016
Unigene ID Hs.303055
Probe set ID -
Ensembl ID ENSG00000165533
GTEx ID ENSG00000165533

Orthologous Gene

Mouse[2]  NM_029553, NM_198311
Rat[1]  NM_001106752, NM_198311

Chromosomal Region

14q31.3  [89,290,497  -  89,344,335]

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

8889548
12477932
14520415
14702039
15489334
16327777
17574030
19077438
19402160
20301537
20301590
20301743
20451172
20801516
21890473
21906983
21963094
23251661

Gene Ontology  (GO ID)

Biological Process

GO:0007411  axon guidance
GO:0060219  camera-type eye photoreceptor cell differentiation
GO:0042384  cilium assembly
GO:0048560  establishment of anatomical structure orientation
GO:0045444  fat cell differentiation
GO:0035264  multicellular organism growth
GO:0021772  olfactory bulb development
GO:0032880  regulation of protein localization
GO:0007608  sensory perception of smell
GO:0050893  sensory processing

Cellular Component

GO:0034464  BBSome
GO:0005813  centrosome
GO:0005929  cilium
GO:0060170  cilium membrane
GO:0005737  cytoplasm
GO:0005932  microtubule basal body
GO:0032391  photoreceptor connecting cilium

Molecular Function

GO:0005515  protein binding