ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Synonym

DJS, MRP2, KIAA1010, Canalicular multidrug resistance protein, Multidrug resistance-associated protein 2, CMOAT1, ABC30, CMOAT, ATP-binding cassette sub-family C member 2, CMRP, cMRP, ABCC2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.11

cerebellum:4.09

brain stem:4.08

corpus callosum/glia:4.05

pineal gland:-

peripheral nerve:4.07

spine:4.04

retina:-

eye:-

artery/aorta:4.49

vein:4.36

lymphnode:4.11

peripheral blood:-

spleen:3.92

thymus:4.22

bone marrow:4.56

adipose:4.52

bone:-

skin:4.48

CAGE

cerebrum:0.05

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0

peripheral blood:-

spleen:0.09

thymus:0

bone marrow:-

adipose:0.26

bone:-

skin:-

RNA-seq

cerebrum:0.05

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.84

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.17

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:-

ovary:37.30

testis:34.60

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:105.60

lung:9.80

bladder:-

kidney:83.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.92

placenta:3.85

prostate:3.86

ovary:4.09

testis:4.33

heart:4.08

muscle:4.30

esophagus:3.94

stomach:4.01

intestine:4.58

colon:4.18

liver/hepato:6.46

lung:3.93

bladder:-

kidney:5.04

pituitary:4.17

thyroid/parathyroid:3.96

adrenal gland:3.90

pancreas:4.73

breast:4.11

salivary:4.23

CAGE

uterus:0

placenta:0.95

prostate:0

ovary:0

testis:0.12

heart:0.03

muscle:0.05

esophagus:0.09

stomach:-

intestine:3.78

colon:1.54

liver/hepato:4.58

lung:0

bladder:0

kidney:3.63

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0.55

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.56

ovary:0.25

testis:0.38

heart:0.03

muscle:0.27

esophagus:-

stomach:-

intestine:-

colon:0.17

liver/hepato:4.97

lung:0.20

bladder:-

kidney:2.93

pituitary:-

thyroid/parathyroid:0.45

adrenal gland:0.76

pancreas:-

breast:0.22

salivary:-

IDs

Refseq ID	NM_000392
Gene ID	1244
Unigene ID	Hs.368243
Probe set ID	206155_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000023839
GTEx ID	ENSG00000023839

Orthologous Gene

Mouse[1]	NM_013806
Rat[1]	NM_013806

Chromosomal Region

10q24.2 [101,542,489 - 101,611,949]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR017940	ABC transporter integral membrane type 1
IPR011527	ABC transporter, transmembrane domain, type 1
IPR003439	ABC transporter-like
IPR003593	ATPase, AAA+ type, core

GO:0030644	cellular chloride ion homeostasis
GO:0006855	multidrug transport
GO:0015732	prostaglandin transport
GO:0046685	response to arsenic
GO:0009408	response to heat
GO:0031427	response to methotrexate
GO:0006979	response to oxidative stress
GO:0070327	thyroid hormone transport
GO:0055085	transmembrane transport
GO:0006810	transport

GO:0016324	apical plasma membrane
GO:0005887	integral to plasma membrane
GO:0046581	intercellular canaliculus
GO:0005886	plasma membrane

GO:0005524	ATP binding
GO:0042626	ATPase activity, coupled to transmembrane movement of substances
GO:0008514	organic anion transmembrane transporter activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding

ATP-binding cassette, sub-family C (CFTR/MRP), member 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function