collagen, type I, alpha 1

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Synonym

collagen, type I, alpha 1, OI4, Collagen alpha-1(I) chain precursor, COL1A1

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.31 cerebellum:3.26 brain stem:3.24 corpus callosum/glia:3.42 pineal gland:- peripheral nerve:4.45 spine:3.28 retina:- eye:- artery/aorta:5.75 vein:5.90 lymphnode:4.40 peripheral blood:- spleen:3.91 thymus:3.37 bone marrow:4.56 adipose:6.21 bone:- skin:6.24
CAGE cerebrum:1.56 cerebellum:- brain stem:1.42 corpus callosum/glia:2.38 pineal gland:2.44 peripheral nerve:- spine:1.81 retina:- eye:- artery/aorta:6.46 vein:5.88 lymphnode:4.93 peripheral blood:- spleen:4.62 thymus:3.96 bone marrow:- adipose:5.20 bone:- skin:-
RNA-seq cerebrum:0.39 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.64 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.18 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.78 placenta:6.75 prostate:4.67 ovary:7.16 testis:3.72 heart:4.40 muscle:3.49 esophagus:4.31 stomach:5.34 intestine:6.41 colon:5.79 liver/hepato:3.73 lung:4.24 bladder:- kidney:3.68 pituitary:3.97 thyroid/parathyroid:3.62 adrenal gland:4.28 pancreas:3.71 breast:6.56 salivary:3.50
CAGE uterus:7.57 placenta:6.47 prostate:5.54 ovary:6.37 testis:5.30 heart:5.14 muscle:3.44 esophagus:4.91 stomach:- intestine:4.20 colon:5.63     liver/hepato:3.08    lung:5.01 bladder:6.08 kidney:3.99 pituitary:2.85 thyroid/parathyroid:2.87 adrenal gland:- pancreas:4.34 breast:5.48 salivary:3.09
RNA-seq uterus:- placenta:- prostate:5.04 ovary:8.02 testis:5.95 heart:2.49 muscle:0.83 esophagus:- stomach:- intestine:- colon:4.15     liver/hepato:3.16        lung:4.07    bladder:- kidney:3.79 pituitary:- thyroid/parathyroid:3.27 adrenal gland:5.80 pancreas:- breast:7.01 salivary:-

IDs

Refseq ID NM_000088
Gene ID 1277
Unigene ID -
Probe set ID 202311_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000108821
GTEx ID ENSG00000108821

Orthologous Gene

Mouse[4]  NM_007742
Rat[3]  NM_053304

Chromosomal Region

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1303238
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Gene Ontology  (GO ID)

Biological Process

GO:0007596  blood coagulation
GO:0001568  blood vessel development
GO:0060346  bone trabecula formation
GO:0060351  cartilage development involved in endochondral bone morphogenesis
GO:0071230  cellular response to amino acid stimulus
GO:0071260  cellular response to mechanical stimulus
GO:0071300  cellular response to retinoic acid
GO:0032964  collagen biosynthetic process
GO:0030574  collagen catabolic process
GO:0030199  collagen fibril organization
GO:0048706  embryonic skeletal system development
GO:0001958  endochondral ossification
GO:0022617  extracellular matrix disassembly
GO:0030198  extracellular matrix organization
GO:0060325  face morphogenesis
GO:0001957  intramembranous ossification
GO:0050900  leukocyte migration
GO:0010812  negative regulation of cell-substrate adhesion
GO:0001649  osteoblast differentiation
GO:0030168  platelet activation
GO:0030335  positive regulation of cell migration
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0070208  protein heterotrimerization
GO:0034504  protein localization in nucleus
GO:0015031  protein transport
GO:0051591  response to cAMP
GO:0031960  response to corticosteroid stimulus
GO:0042542  response to hydrogen peroxide
GO:0007584  response to nutrient
GO:0043434  response to peptide hormone stimulus
GO:0007605  sensory perception of sound
GO:0001501  skeletal system development
GO:0043589  skin morphogenesis
GO:0034505  tooth mineralization
GO:0007601  visual perception

Cellular Component

GO:0005584  collagen type I
GO:0005788  endoplasmic reticulum lumen
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space

Molecular Function

GO:0005201  extracellular matrix structural constituent
GO:0042802  identical protein binding
GO:0046872  metal ion binding
GO:0048407  platelet-derived growth factor binding
GO:0005515  protein binding