Rho guanine nucleotide exchange factor (GEF) 19

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Synonym

ARHGEF19, WGEF, Rho guanine nucleotide exchange factor (GEF) 19, FLJ33962, RP4-733M16.1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:29.40 artery/aorta:30 vein:- lymphnode:- peripheral blood:18.20 spleen:- thymus:12.90 bone marrow:- adipose:- bone:25.60 skin:-
GeneChip nodata
CAGE cerebrum:0.24 cerebellum:- brain stem:0.19 corpus callosum/glia:0.43 pineal gland:0.56 peripheral nerve:- spine:0.22 retina:- eye:- artery/aorta:1.38 vein:1.03 lymphnode:1.15 peripheral blood:- spleen:0.99 thymus:0.77 bone marrow:- adipose:0.96 bone:- skin:-
RNA-seq cerebrum:0.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.77 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.50 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:7.30 prostate:56.30 ovary:37.30 testis:- heart:51.10 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:14.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:1.61 placenta:0.85 prostate:1.80 ovary:1.50 testis:0.76 heart:1.00 muscle:0.38 esophagus:2.77 stomach:- intestine:1.05 colon:1.27     liver/hepato:0.36    lung:1.40 bladder:1.12 kidney:1.03 pituitary:0 thyroid/parathyroid:2.26 adrenal gland:- pancreas:1.98 breast:1.16 salivary:2.63
RNA-seq uterus:- placenta:- prostate:1.74 ovary:1.53 testis:0.92 heart:0.46 muscle:0.16 esophagus:- stomach:- intestine:- colon:0.78     liver/hepato:0.67        lung:0.83    bladder:- kidney:1.28 pituitary:- thyroid/parathyroid:1.58 adrenal gland:1.28 pancreas:- breast:0.83 salivary:-

Gene Information

IDs

Refseq ID NM_153213
Gene ID 128272
Unigene ID Hs.591532
Probe set ID -
Ensembl ID ENSG00000142632
GTEx ID ENSG00000142632

Orthologous Gene

Mouse[1]  NM_172520
Rat [0]  

Chromosomal Region

1p36.13  [16,524,349  -  16,539,140]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology

Link to Pubmed  (Pubmed ID)

12477932
14702039
15485661
18187620
18256687
21906983
24405610

Gene Ontology  (GO ID)

Biological Process

GO:0032321  positive regulation of Rho GTPase activity
GO:0032956  regulation of actin cytoskeleton organization
GO:0042060  wound healing

Molecular Function

GO:0005096  GTPase activator activity
GO:0005543  phospholipid binding
GO:0005089  Rho guanyl-nucleotide exchange factor activity