collagen, type XI, alpha 2

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Synonym

collagen, type XI, alpha 2, DFNB53, PARP, HKE5, COL11A2, DFNA13, STL3, Collagen alpha-2(XI) chain precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:15.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:214.70 spine:- retina:- eye:11.80 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:166.30 skin:9.60
GeneChip cerebrum:5.44 cerebellum:5.73 brain stem:5.53 corpus callosum/glia:5.60 pineal gland:- peripheral nerve:5.21 spine:5.58 retina:- eye:- artery/aorta:5.30 vein:5.25 lymphnode:4.96 peripheral blood:- spleen:4.81 thymus:5.18 bone marrow:5.51 adipose:5.38 bone:- skin:5.28
CAGE cerebrum:0.78 cerebellum:- brain stem:0.83 corpus callosum/glia:1.33 pineal gland:0.55 peripheral nerve:- spine:1.21 retina:- eye:- artery/aorta:2.02 vein:0 lymphnode:0.12 peripheral blood:- spleen:0.17 thymus:0.37 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:37.30 testis:8.70 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.94 placenta:5.02 prostate:5.03 ovary:4.95 testis:5.14 heart:5.05 muscle:5.30 esophagus:5.10 stomach:4.95 intestine:5 colon:4.96 liver/hepato:5.18 lung:5.13 bladder:- kidney:5.05 pituitary:6.40 thyroid/parathyroid:5.28 adrenal gland:5.13 pancreas:4.81 breast:5.03 salivary:4.96
CAGE uterus:0.13 placenta:0.16 prostate:0.08 ovary:0.07 testis:0.73 heart:0.50 muscle:0.21 esophagus:0 stomach:- intestine:0.53 colon:0.04     liver/hepato:0.14    lung:0.31 bladder:0.09 kidney:0.15 pituitary:2.50 thyroid/parathyroid:0.32 adrenal gland:- pancreas:0.58 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_080679
Gene ID 1302
Unigene ID Hs.390171
Probe set ID 213870_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000204248
ENSG00000230930
GTEx ID ENSG00000204248
ENSG00000230930

Orthologous Gene

Mouse[1]  NM_009926
Rat[1]  NM_212528

Chromosomal Region

6p21.32  [33,130,458  -  33,160,276]
HSCHR6_MHC_COX  [33,052,091  -  33,081,908]
HSCHR6_MHC_SSTO  [33,269,767  -  33,296,554]
HSCHR6_MHC_QBL  [33,059,284  -  33,089,101]
HSCHR6_MHC_MCF  [33,300,827  -  33,330,643]
HSCHR6_MHC_DBB  [33,108,368  -  33,138,186]
HSCHR6_MHC_MANN  [33,284,377  -  33,314,194]

Gene Family (Interpro ID)

IPR008985  Concanavalin A-like lectin/glucanase
IPR013320  Concanavalin A-like lectin/glucanase, subgroup
IPR001791  Laminin G

Link to Pubmed  (Pubmed ID)

2591970
2760050
7559422
7560887
7721876
7836472
7859284
8325374
8663204
8838804
9101290
9106521
9188673
9506662
9585596
9805126
10581026
10677296
11289713
11341341
11780999
12477932
12554743
12673280
14574404
15558753
15922184
16033917
16133074
16609882
16734381
17471097
17703188
18040076
18193043
18309376
18381781
18469698
18830248
19180518
19204726
19615732
19851445
19913121
20301479
20301607
20618517
20628086
20634891
20672350
21204229
21293383
21900206
22112025
22246659
22796475
22808956
23624467
23740775
24097066

Gene Ontology  (GO ID)

Biological Process

GO:0051216  cartilage development
GO:0030574  collagen catabolic process
GO:0030199  collagen fibril organization
GO:0022617  extracellular matrix disassembly
GO:0030198  extracellular matrix organization
GO:0060021  palate development
GO:0007605  sensory perception of sound
GO:0001501  skeletal system development
GO:0060023  soft palate development

Cellular Component

GO:0005592  collagen type XI
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region

Molecular Function

GO:0030020  extracellular matrix structural constituent conferring tensile strength
GO:0046872  metal ion binding
GO:0030674  protein binding, bridging