cAMP responsive element binding protein 1

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Synonym

CREB, MGC9284, CREB1, cAMP responsive element binding protein 1, cAMP response element-binding protein

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:29.60 cerebellum:25.20 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:52.90 artery/aorta:119.90 vein:- lymphnode:151.70 peripheral blood:18.20 spleen:- thymus:64.40 bone marrow:19.70 adipose:- bone:12.80 skin:24
GeneChip cerebrum:4.93 cerebellum:5.19 brain stem:5.04 corpus callosum/glia:4.93 pineal gland:- peripheral nerve:4.50 spine:4.71 retina:- eye:- artery/aorta:5.12 vein:5.16 lymphnode:4.74 peripheral blood:- spleen:5.02 thymus:5.88 bone marrow:4.98 adipose:5.05 bone:- skin:4.82
CAGE cerebrum:3.82 cerebellum:- brain stem:3.91 corpus callosum/glia:3.79 pineal gland:4.19 peripheral nerve:- spine:3.90 retina:- eye:- artery/aorta:3.75 vein:4.11 lymphnode:3.71 peripheral blood:- spleen:4.03 thymus:4.53 bone marrow:- adipose:4.19 bone:- skin:-
RNA-seq cerebrum:1.63 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.16 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.45 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:18.20 prostate:56.30 ovary:37.30 testis:21.60 heart:38.30 muscle:- esophagus:- stomach:21.20 intestine:32.40 colon:17     liver/hepato:10.60        lung:44    bladder:- kidney:72.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:80 breast:18.60 salivary:-
GeneChip uterus:5.18 placenta:4.64 prostate:5.16 ovary:5.16 testis:6.81 heart:5.02 muscle:4.58 esophagus:5.04 stomach:4.95 intestine:4.77 colon:4.94 liver/hepato:4.58 lung:4.72 bladder:- kidney:4.57 pituitary:4.61 thyroid/parathyroid:4.51 adrenal gland:4.59 pancreas:4.73 breast:4.68 salivary:4.45
CAGE uterus:4.08 placenta:3.59 prostate:3.95 ovary:3.94 testis:4.50 heart:3.81 muscle:3.43 esophagus:3.69 stomach:- intestine:3.70 colon:3.63     liver/hepato:3.16    lung:3.88 bladder:3.88 kidney:3.57 pituitary:3.99 thyroid/parathyroid:3.80 adrenal gland:- pancreas:3.13 breast:3.64 salivary:3.58
RNA-seq uterus:- placenta:- prostate:2.85 ovary:2.81 testis:2.37 heart:1.82 muscle:1.70 esophagus:- stomach:- intestine:- colon:2.66     liver/hepato:1.39        lung:2.28    bladder:- kidney:2.26 pituitary:- thyroid/parathyroid:2.22 adrenal gland:2.22 pancreas:- breast:2.50 salivary:-

IDs

Refseq ID NM_004379
Gene ID 1385
Unigene ID Hs.516646
Probe set ID 214513_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118260
GTEx ID ENSG00000118260

Orthologous Gene

Mouse[9]  NM_001037726, NM_009952, NM_133828
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1386673
1461747
1655749
1831258
1966745
2138276
2142119
2142528
2974179
7505393
7551568
7554179
7565761
7608156
7619208
7621901
7769693
7809053
8381074
8384217
8449898
8552098
8628277
8663317
8688081
8798441
8887554
9065434
9388250
9413984
9558095
9671480
9687510
9770464
9786917
9792677
9829964
9873047
10074179
10506141
10567391
10650954
10720489
10722738
10781615
10848610
10866654
10886376
10909971
10945975
11013247
11018520
11046156
11156964
11160957
11175347
11259575
11313407
11377386
11500364
11564156
11572863
11698596
11909979
11988318
12091337
12145339
12162494
12183445
12196545
12198160
12200150
12220644
12235136
12368293
12391146
12391222
12437352
12477932
12519783
12552083
12567184
12622660
12665587
12676584
12690113
12720543
12743114
12773552
12776737
12805224
12829027
12851637
14506290
14523007
14580193
14597631
14597636
14635195
14646589
14702039
14742439
14754893
14761884
14764597
14962944
15073328
15077295
15082775
15153340
15276183
15340044
15454081
15489334
15500908
15579595
15585582
15588513
15615708
15688015
15691874
15691881
15694837
15703171
15733869
15753290
15806162
15837624
15879136
15897899
15901830
15917247
15961999
15964553
15999345
16007092
16134057
16158061
16169070
16207717
16207795
16223362
16227528
16282323
16293623
16306050
16325578
16330542
16339753
16449647
16483570
16598418
16611888
16675956
16799563
16820098
16822311
16896160
16920714
16963449
16978443
16980615
17082618
17169345
17202341
17276404
17289023
17300755
17310988
17389598
17426037
17449469
17455223
17460549
17476304
17507637
17548750
17565597
17565598
17565599
17565603
17573727
17592483
17646388
17661722
17712720
17724745
17727817
17786359
17805329
17822787
17827388
17889508
17909078
17975014
18022816
18024382
18029348
18034423
18070920
18160048
18189280
18191017
18287226
18375384
18396147
18457359
18483184
18485898
18511806
18554190
18599546
18606955
18626018
18660489
18676828
18678793
18713830
18717645
18775326
18792986
18801732
18922788
18930904
18988190
19001277
19070599
19100722
19113914
19136032
19138976
19156168
19164291
19194961
19196967
19199539
19201889
19211892
19223597
19244110
19251839
19279000
19289467
19298866
19340314
19351775
19416972
19426590
19473990
19517574
19531482
19548263
19553322
19561568
19578717
19614745
19632326
19632997
19718656
19762740
19786833
19797430
19815709
19822084
19822898
19842072
19844206
19861239
19874574
19875824
19913121
19956847
20018896
20032081
20033853
20037212
20089855
20097716
20100571
20101207
20136501
20160059
20198332
20198339
20211142
20219685
20237496
20398657
20402410
20403362
20407090
20407870
20447464
20468064
20473547
20498639
20533262
20536573
20541704
20573984
20599715
20624818
20628086
20643483
20682687
20685939
20693566
20805990
20881124
20936779
20943350
20945072
20974683
20979795
21034562
21044077
21075212
21079758
21084670
21139048
21172805
21212407
21215389
21268077
21295542
21315782
21325281
21398611
21483768
21497119
21598377
21644508
21705328
21706049
21734652
21784978
21816823
21832046
21890473
21956116
21988832
21997693
21998402
22027994
22072831
22127929
22180334
22185778
22198373
22219277
22253425
22267179
22271686
22285928
22293360
22294156
22325466
22349818
22383952
22386572
22469229
22505473
22510762
22531917
22539488
22561749
22570239
22574704
22609331
22627767
22669896
22726539
22743041
22787115
22922957
22939629
23000965
23011268
23019365
23020846
23032945
23038261
23049845
23055509
23086924
23100280
23127979
23143030
23168992
23185366
23195957
23213254
23220172
23382074
23382855
23403511
23417028
23462962
23469012
23494562
23504989
23526216
23532963
23537502
23543137
23619509
23661758
23708553
23727510
23814058
23838680
23846693
23857777
23894352
23896026
23979134
24025972
24041570
24055910
24065533
24085294
24233491
24250222
24289115
24315104
24338025
24651445
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007202  activation of phospholipase C activity
GO:0007411  axon guidance
GO:0007173  epidermal growth factor receptor signaling pathway
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0045087  innate immune response
GO:0007595  lactation
GO:0060430  lung saccule development
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0002756  MyD88-independent toll-like receptor signaling pathway
GO:0010944  negative regulation of transcription by competitive promoter binding
GO:0048011  nerve growth factor receptor signaling pathway
GO:0007219  Notch signaling pathway
GO:0048015  phosphoinositide-mediated signaling
GO:0021983  pituitary gland development
GO:0045600  positive regulation of fat cell differentiation
GO:0046887  positive regulation of hormone secretion
GO:0046889  positive regulation of lipid biosynthetic process
GO:0040018  positive regulation of multicellular organism growth
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006468  protein amino acid phosphorylation
GO:0050821  protein stabilization
GO:0008361  regulation of cell size
GO:0042493  response to drug
GO:0010033  response to organic substance
GO:0033363  secretory granule organization
GO:0007165  signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0007268  synaptic transmission
GO:0034166  toll-like receptor 10 signaling pathway
GO:0034134  toll-like receptor 2 signaling pathway
GO:0034138  toll-like receptor 3 signaling pathway
GO:0034142  toll-like receptor 4 signaling pathway
GO:0034146  toll-like receptor 5 signaling pathway
GO:0034162  toll-like receptor 9 signaling pathway
GO:0002224  toll-like receptor signaling pathway
GO:0060509  Type I pneumocyte differentiation
GO:0019048  virus-host interaction

Cellular Component

GO:0005719  nuclear euchromatin
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005667  transcription factor complex

Molecular Function

GO:0005515  protein binding
GO:0003705  RNA polymerase II transcription factor activity, enhancer binding
GO:0003712  transcription cofactor activity
GO:0003700  transcription factor activity