cAMP responsive element binding protein 1

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Synonym

CREB, MGC9284, CREB1, cAMP responsive element binding protein 1, cAMP response element-binding protein

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:29.60

cerebellum:25.20

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:52.90

artery/aorta:119.90

vein:-

lymphnode:151.70

peripheral blood:18.20

spleen:-

thymus:64.40

bone marrow:19.70

adipose:-

bone:12.80

skin:24

GeneChip

cerebrum:4.93

cerebellum:5.19

brain stem:5.04

corpus callosum/glia:4.93

pineal gland:-

peripheral nerve:4.50

spine:4.71

retina:-

eye:-

artery/aorta:5.12

vein:5.16

lymphnode:4.74

peripheral blood:-

spleen:5.02

thymus:5.88

bone marrow:4.98

adipose:5.05

bone:-

skin:4.82

CAGE

cerebrum:3.82

cerebellum:-

brain stem:3.91

corpus callosum/glia:3.79

pineal gland:4.19

peripheral nerve:-

spine:3.90

retina:-

eye:-

artery/aorta:3.75

vein:4.11

lymphnode:3.71

peripheral blood:-

spleen:4.03

thymus:4.53

bone marrow:-

adipose:4.19

bone:-

skin:-

RNA-seq

cerebrum:1.63

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.16

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.45

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:18.20

prostate:56.30

ovary:37.30

testis:21.60

heart:38.30

muscle:-

esophagus:-

stomach:21.20

intestine:32.40

colon:17

liver/hepato:10.60

lung:44

bladder:-

kidney:72.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:80

breast:18.60

salivary:-

GeneChip

uterus:5.18

placenta:4.64

prostate:5.16

ovary:5.16

testis:6.81

heart:5.02

muscle:4.58

esophagus:5.04

stomach:4.95

intestine:4.77

colon:4.94

liver/hepato:4.58

lung:4.72

bladder:-

kidney:4.57

pituitary:4.61

thyroid/parathyroid:4.51

adrenal gland:4.59

pancreas:4.73

breast:4.68

salivary:4.45

CAGE

uterus:4.08

placenta:3.59

prostate:3.95

ovary:3.94

testis:4.50

heart:3.81

muscle:3.43

esophagus:3.69

stomach:-

intestine:3.70

colon:3.63

liver/hepato:3.16

lung:3.88

bladder:3.88

kidney:3.57

pituitary:3.99

thyroid/parathyroid:3.80

adrenal gland:-

pancreas:3.13

breast:3.64

salivary:3.58

RNA-seq

uterus:-

placenta:-

prostate:2.85

ovary:2.81

testis:2.37

heart:1.82

muscle:1.70

esophagus:-

stomach:-

intestine:-

colon:2.66

liver/hepato:1.39

lung:2.28

bladder:-

kidney:2.26

pituitary:-

thyroid/parathyroid:2.22

adrenal gland:2.22

pancreas:-

breast:2.50

salivary:-

IDs

Refseq ID	NM_004379
Gene ID	1385
Unigene ID	Hs.516646
Probe set ID	214513_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000118260
GTEx ID	ENSG00000118260

Orthologous Gene

Mouse[9]	NM_001037726, NM_009952, NM_133828
Rat [0]

Chromosomal Region

2q33.3 [208,394,461 - 208,468,155]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004827

Basic-leucine zipper (bZIP) transcription factor

Gene Ontology (GO ID)

Biological Process

GO:0007202	activation of phospholipase C activity
GO:0007411	axon guidance
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0045087	innate immune response
GO:0007595	lactation
GO:0060430	lung saccule development
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0010944	negative regulation of transcription by competitive promoter binding
GO:0048011	nerve growth factor receptor signaling pathway
GO:0007219	Notch signaling pathway
GO:0048015	phosphoinositide-mediated signaling
GO:0021983	pituitary gland development
GO:0045600	positive regulation of fat cell differentiation
GO:0046887	positive regulation of hormone secretion
GO:0046889	positive regulation of lipid biosynthetic process
GO:0040018	positive regulation of multicellular organism growth
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006468	protein amino acid phosphorylation
GO:0050821	protein stabilization
GO:0008361	regulation of cell size
GO:0042493	response to drug
GO:0010033	response to organic substance
GO:0033363	secretory granule organization
GO:0007165	signal transduction
GO:0051403	stress-activated MAPK cascade
GO:0007268	synaptic transmission
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0060509	Type I pneumocyte differentiation
GO:0019048	virus-host interaction

Cellular Component

GO:0005719	nuclear euchromatin
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0005667	transcription factor complex

Molecular Function

GO:0005515	protein binding
GO:0003705	RNA polymerase II transcription factor activity, enhancer binding
GO:0003712	transcription cofactor activity
GO:0003700	transcription factor activity

cAMP responsive element binding protein 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function