corticotropin releasing hormone binding protein

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Synonym

CRF-binding protein, CRF-BP, corticotropin releasing hormone binding protein, Corticotropin-releasing hormone-binding protein, CRHBP, CRFBP, CRH-BP, corticotropin releasing hormone-binding protein

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:43.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:30.30 peripheral blood:- spleen:18.90 thymus:- bone marrow:- adipose:- bone:- skin:24
GeneChip cerebrum:4.56 cerebellum:3.83 brain stem:4.30 corpus callosum/glia:4.57 pineal gland:- peripheral nerve:3.81 spine:4.18 retina:- eye:- artery/aorta:3.99 vein:4.16 lymphnode:4.16 peripheral blood:- spleen:5.63 thymus:3.79 bone marrow:4.47 adipose:4.37 bone:- skin:4.01
CAGE cerebrum:1.93 cerebellum:- brain stem:1.86 corpus callosum/glia:2.45 pineal gland:0 peripheral nerve:- spine:1.10 retina:- eye:- artery/aorta:1.61 vein:1.89 lymphnode:0.39 peripheral blood:- spleen:3.42 thymus:0.37 bone marrow:- adipose:1.21 bone:- skin:-
RNA-seq cerebrum:2.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.65 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:69.20 prostate:- ovary:37.30 testis:8.70 heart:- muscle:20.10 esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:73.90        lung:-    bladder:- kidney:145.60 pituitary:- thyroid/parathyroid:- adrenal gland:253.90 pancreas:- breast:37.20 salivary:-
GeneChip uterus:3.95 placenta:5.18 prostate:3.82 ovary:3.68 testis:3.88 heart:3.94 muscle:3.72 esophagus:3.71 stomach:3.63 intestine:3.45 colon:3.57 liver/hepato:7.19 lung:3.78 bladder:- kidney:5.24 pituitary:3.91 thyroid/parathyroid:3.91 adrenal gland:5.45 pancreas:4.04 breast:3.79 salivary:3.96
CAGE uterus:1.77 placenta:3.63 prostate:0.94 ovary:1.25 testis:1.00 heart:1.34 muscle:0.13 esophagus:0.63 stomach:- intestine:0.53 colon:0.46     liver/hepato:5.21    lung:0.68 bladder:1.02 kidney:3.56 pituitary:0 thyroid/parathyroid:0.60 adrenal gland:- pancreas:0 breast:1.16 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.95 ovary:1.35 testis:1.26 heart:0.96 muscle:0.11 esophagus:- stomach:- intestine:- colon:0.19     liver/hepato:5.48        lung:0.47    bladder:- kidney:3.41 pituitary:- thyroid/parathyroid:1.05 adrenal gland:2.44 pancreas:- breast:2.66 salivary:-

Gene Information

IDs

Refseq ID NM_001882
Gene ID 1393
Unigene ID Hs.115617
Probe set ID 205984_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000145708
GTEx ID ENSG00000145708

Orthologous Gene

Mouse[1]  NM_198408
Rat [0]  

Chromosomal Region

5q13.3  [76,248,538  -  76,276,983]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1846945
2549150
7477348
7774945
8125298
8198617
8307998
8557170
8612563
9253360
12477932
12784189
13150566
14573312
15072543
15345745
15489334
16368564
16482088
16734917
17207965
17599466
17728670
18234674
18559919
18818748
18838498
18974851
19019335
19086053
19131402
19453261
19527514
19578876
19723618
19874574
20140262
20351714
20368512
20379614
20403506
21039637
21810631
21978546
22286724
22984453
23131710

Gene Ontology  (GO ID)

Biological Process

GO:0007610  behavior
GO:0048149  behavioral response to ethanol
GO:0071277  cellular response to calcium ion
GO:0071320  cellular response to cAMP
GO:0071314  cellular response to cocaine
GO:0071392  cellular response to estradiol stimulus
GO:0071391  cellular response to estrogen stimulus
GO:0033554  cellular response to stress
GO:0071356  cellular response to tumor necrosis factor
GO:0007565  female pregnancy
GO:0042445  hormone metabolic process
GO:0009755  hormone-mediated signaling pathway
GO:0006954  inflammatory response
GO:0007611  learning or memory
GO:0002125  maternal aggressive behavior
GO:0051460  negative regulation of adrenocorticotropin secretion
GO:0045055  regulated secretory pathway
GO:0051459  regulation of adrenocorticotropin secretion
GO:0050795  regulation of behavior
GO:0007165  signal transduction
GO:0001963  synaptic transmission, dopaminergic

Cellular Component

GO:0030425  dendrite
GO:0031045  dense core granule
GO:0005783  endoplasmic reticulum
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0005622  intracellular
GO:0005874  microtubule
GO:0005771  multivesicular body
GO:0043679  nerve terminal
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0005767  secondary lysosome
GO:0030141  secretory granule
GO:0043196  varicosity

Molecular Function

GO:0051424  corticotropin-releasing hormone binding
GO:0042277  peptide binding
GO:0005515  protein binding