zinc finger and BTB domain containing 46

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Synonym

BTBD4, RINZF, BTB/POZ domain-containing protein 4, BTB (POZ) domain containing 4, dJ583P15.8, ZNF340, zinc finger and BTB domain containing 46, Zinc finger protein 340, FLJ13502, ZBTB46, Zinc finger and BTB domain-containing protein 46, dJ583P15.7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:22.50 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:- retina:118.60 eye:29.40 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:56.70 thymus:- bone marrow:- adipose:80.70 bone:- skin:24
GeneChip nodata
CAGE cerebrum:1.41 cerebellum:- brain stem:1.38 corpus callosum/glia:1.13 pineal gland:1.88 peripheral nerve:- spine:1.29 retina:- eye:- artery/aorta:1.79 vein:2.01 lymphnode:0.90 peripheral blood:- spleen:2.13 thymus:0.86 bone marrow:- adipose:2.05 bone:- skin:-
RNA-seq cerebrum:1.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.61 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.93 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:21.90 prostate:11.30 ovary:- testis:26 heart:12.80 muscle:- esophagus:- stomach:21.20 intestine:- colon:8.50     liver/hepato:-        lung:29.30    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:- salivary:-
GeneChip nodata
CAGE uterus:2.05 placenta:1.53 prostate:1.34 ovary:2.20 testis:1.37 heart:1.92 muscle:1.31 esophagus:0.77 stomach:- intestine:0.77 colon:0.97     liver/hepato:1.01    lung:1.86 bladder:0.73 kidney:1.53 pituitary:1.21 thyroid/parathyroid:1.65 adrenal gland:- pancreas:1.59 breast:1.68 salivary:1.15
RNA-seq uterus:- placenta:- prostate:1.06 ovary:2.95 testis:1.51 heart:1.47 muscle:0.32 esophagus:- stomach:- intestine:- colon:0.78     liver/hepato:0.66        lung:1.54    bladder:- kidney:1.89 pituitary:- thyroid/parathyroid:2.00 adrenal gland:2.02 pancreas:- breast:1.66 salivary:-

Gene Information

IDs

Refseq ID NM_025224
Gene ID 140685
Unigene ID Hs.585028
Probe set ID -
Ensembl ID ENSG00000130584
GTEx ID ENSG00000130584

Orthologous Gene

Mouse[3]  NM_027656, NM_028125
Rat [0]  

Chromosomal Region

20q13.33  [62,375,019  -  62,462,597]

Gene Family (Interpro ID)

IPR011333  BTB/POZ fold
IPR000210  BTB/POZ-like
IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

11780052
12136098
12477932
14702039
15489334
19322201
21145461
21297633
21833088
22370726
23251661
23739915

Gene Ontology  (GO ID)

Biological Process

GO:0030853  negative regulation of granulocyte differentiation
GO:0045650  negative regulation of macrophage differentiation
GO:0045656  negative regulation of monocyte differentiation
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0046872  metal ion binding
GO:0003676  nucleic acid binding