proteasome (prosome, macropain) subunit, alpha type, 8

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Synonym

Proteasome subunit alpha type 7-like, MGC26605, PSMA8, PSMA7L

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:20.20 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:4.80
GeneChip nodata
CAGE cerebrum:0.03 cerebellum:- brain stem:0.24 corpus callosum/glia:0.07 pineal gland:0.79 peripheral nerve:- spine:0.09 retina:- eye:- artery/aorta:0.18 vein:0.47 lymphnode:0.48 peripheral blood:- spleen:0.61 thymus:0.37 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:77.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0 placenta:0 prostate:0.08 ovary:0.07 testis:3.31 heart:0 muscle:0 esophagus:0 stomach:- intestine:0.07 colon:0.08     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0.00 testis:0.88 heart:0.00 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_144662
Gene ID 143471
Unigene ID Hs.464813
Probe set ID -
Ensembl ID ENSG00000154611
GTEx ID ENSG00000154611

Orthologous Gene

Mouse[1]  NM_001163609
Rat [0]  

Chromosomal Region

18q11.2  [23,713,816  -  23,773,319]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11285280
12376572
12477932
12791267
15489334
16177791
17948026
19941857
21139048
21890473
21906983
21963094
21987572
22505724
22659184
22939629
23000965
23585552
24024966

Gene Ontology  (GO ID)

Biological Process

GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0006915  apoptosis
GO:0034641  cellular nitrogen compound metabolic process
GO:0006977  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467  gene expression
GO:0000278  mitotic cell cycle
GO:0016071  mRNA metabolic process
GO:0043066  negative regulation of apoptosis
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0000209  protein polyubiquitination
GO:0042981  regulation of apoptosis
GO:0006521  regulation of cellular amino acid metabolic process
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0016070  RNA metabolic process
GO:0016032  viral reproduction

Cellular Component

GO:0005829  cytosol
GO:0005634  nucleus
GO:0019773  proteasome core complex, alpha-subunit complex

Molecular Function

GO:0004298  threonine-type endopeptidase activity