colony stimulating factor 1 receptor

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Synonym

FIM2, CSF1R, CSF-1-R, CD115 antigen, C-FMS, CSFR, Fms proto-oncogene, c-fms, CD115, FMS

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:13

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:47

artery/aorta:-

vein:-

lymphnode:40.40

peripheral blood:-

spleen:-

thymus:-

bone marrow:59

adipose:-

bone:12.80

skin:33.60

GeneChip

cerebrum:7.60

cerebellum:6.23

brain stem:7.69

corpus callosum/glia:8.45

pineal gland:-

peripheral nerve:8.39

spine:8.63

retina:-

eye:-

artery/aorta:7.74

vein:6.85

lymphnode:7.99

peripheral blood:-

spleen:7.84

thymus:6.64

bone marrow:6.89

adipose:7.78

bone:-

skin:7.26

CAGE

cerebrum:4.00

cerebellum:-

brain stem:4.75

corpus callosum/glia:5.16

pineal gland:3.80

peripheral nerve:-

spine:4.71

retina:-

eye:-

artery/aorta:4.01

vein:4.50

lymphnode:4.47

peripheral blood:-

spleen:6.28

thymus:3.09

bone marrow:-

adipose:4.96

bone:-

skin:-

RNA-seq

cerebrum:2.79

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.26

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.03

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:18.20

prostate:67.60

ovary:37.30

testis:21.60

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:33.90

liver/hepato:-

lung:53.80

bladder:-

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:26.70

breast:18.60

salivary:-

GeneChip

uterus:6.90

placenta:9.06

prostate:6.79

ovary:7.21

testis:6.30

heart:6.69

muscle:6.17

esophagus:6.97

stomach:6.95

intestine:7.28

colon:6.80

liver/hepato:7.11

lung:7.86

bladder:-

kidney:6.26

pituitary:6.94

thyroid/parathyroid:6.58

adrenal gland:7.37

pancreas:6.71

breast:7.42

salivary:6.60

CAGE

uterus:3.63

placenta:5.78

prostate:4.18

ovary:3.47

testis:3.35

heart:3.58

muscle:2.88

esophagus:3.29

stomach:-

intestine:4.10

colon:3.71

liver/hepato:4.48

lung:4.33

bladder:3.49

kidney:3.81

pituitary:3.08

thyroid/parathyroid:2.76

adrenal gland:-

pancreas:3.06

breast:3.90

salivary:2.93

RNA-seq

uterus:-

placenta:-

prostate:3.14

ovary:2.60

testis:2.46

heart:2.30

muscle:1.48

esophagus:-

stomach:-

intestine:-

colon:1.38

liver/hepato:2.73

lung:2.86

bladder:-

kidney:2.64

pituitary:-

thyroid/parathyroid:1.76

adrenal gland:3.65

pancreas:-

breast:3.60

salivary:-

IDs

Refseq ID	NM_005211
Gene ID	1436
Unigene ID	Hs.586219
Probe set ID	203104_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000182578
GTEx ID	ENSG00000182578

Orthologous Gene

Mouse[3]	NM_001037859
Rat[1]	NM_001029901

Chromosomal Region

5q32 [149,432,854 - 149,492,935]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR020685	Tyrosine-protein kinase
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR016243	Tyrosine-protein kinase, CSF-1/PDGF receptor
IPR020933	Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0008283	cell proliferation
GO:0045217	cell-cell junction maintenance
GO:0071345	cellular response to cytokine stimulus
GO:0019221	cytokine-mediated signaling pathway
GO:0030097	hemopoiesis
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0030225	macrophage differentiation
GO:0060603	mammary gland duct morphogenesis
GO:0030224	monocyte differentiation
GO:0007275	multicellular organismal development
GO:0030316	osteoclast differentiation
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0046488	phosphatidylinositol metabolic process
GO:0048015	phosphoinositide-mediated signaling
GO:0030335	positive regulation of cell migration
GO:0008284	positive regulation of cell proliferation
GO:0090197	positive regulation of chemokine secretion
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0046777	protein amino acid autophosphorylation
GO:0045124	regulation of bone resorption
GO:0008360	regulation of cell shape
GO:0031529	ruffle organization
GO:0007165	signal transduction
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0009986	cell surface
GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane
GO:0043235	receptor complex

Molecular Function

GO:0005524	ATP binding
GO:0019955	cytokine binding
GO:0005011	macrophage colony stimulating factor receptor activity
GO:0042803	protein homodimerization activity

colony stimulating factor 1 receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function