CDC42 effector protein (Rho GTPase binding) 5

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Synonym

CDC42EP5, MGC21945, CEP5, Borg3, Cdc42 effector protein 5, BORG3, Binder of Rho GTPases 3, MGC71153, CDC42 effector protein (Rho GTPase binding) 5

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:47 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:25.60 skin:-
GeneChip nodata
CAGE cerebrum:0.65 cerebellum:- brain stem:1.05 corpus callosum/glia:1.01 pineal gland:1.18 peripheral nerve:- spine:1.14 retina:- eye:- artery/aorta:3.28 vein:2.75 lymphnode:2.93 peripheral blood:- spleen:2.45 thymus:2.21 bone marrow:- adipose:3.22 bone:- skin:-
RNA-seq cerebrum:0.58 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.41 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.24 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:3.60 prostate:45.10 ovary:37.30 testis:- heart:- muscle:- esophagus:- stomach:127.50 intestine:- colon:76.30     liver/hepato:-        lung:24.40    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:- salivary:-
GeneChip nodata
CAGE uterus:3.12 placenta:2.61 prostate:3.67 ovary:2.69 testis:2.78 heart:2.81 muscle:1.97 esophagus:2.93 stomach:- intestine:4.13 colon:4.46     liver/hepato:1.63    lung:3.06 bladder:3.69 kidney:2.11 pituitary:0.92 thyroid/parathyroid:2.04 adrenal gland:- pancreas:2.18 breast:3.12 salivary:2.80
RNA-seq uterus:- placenta:- prostate:4.11 ovary:1.51 testis:1.82 heart:1.54 muscle:1.10 esophagus:- stomach:- intestine:- colon:4.18     liver/hepato:0.68        lung:4.45    bladder:- kidney:2.03 pituitary:- thyroid/parathyroid:1.74 adrenal gland:2.76 pancreas:- breast:2.55 salivary:-

Gene Information

IDs

Refseq ID NM_145057
Gene ID 148170
Unigene ID Hs.415791
Probe set ID -
Ensembl ID ENSG00000167617
GTEx ID ENSG00000167617

Orthologous Gene

Mouse[1]  NM_021454
Rat[1]  NM_001108469

Chromosomal Region

19q13.42  [54,976,210  -  54,984,411]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10490598
11035016
11584266
12477932
15489334
16344560

Gene Ontology  (GO ID)

Biological Process

GO:0007254  JNK cascade
GO:0030838  positive regulation of actin filament polymerization
GO:0031274  positive regulation of pseudopodium assembly
GO:0008360  regulation of cell shape
GO:0007266  Rho protein signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005856  cytoskeleton
GO:0012505  endomembrane system
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0017049  GTP-Rho binding