connective tissue growth factor

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Synonym

MGC102839, connective tissue growth factor, IGFBP8, Hypertrophic chondrocyte-specific protein 24, HCS24, CTGF, CCN2, Connective tissue growth factor precursor, NOV2

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.53 cerebellum:4.47 brain stem:5.45 corpus callosum/glia:5.56 pineal gland:- peripheral nerve:8.30 spine:5.86 retina:- eye:- artery/aorta:8.76 vein:9.66 lymphnode:6.53 peripheral blood:- spleen:9.54 thymus:5.90 bone marrow:6.04 adipose:8.19 bone:- skin:7.58
CAGE cerebrum:3.60 cerebellum:- brain stem:3.45 corpus callosum/glia:3.89 pineal gland:3.82 peripheral nerve:- spine:3.79 retina:- eye:- artery/aorta:7.57 vein:5.37 lymphnode:4.99 peripheral blood:- spleen:6.97 thymus:3.48 bone marrow:- adipose:5.51 bone:- skin:-
RNA-seq cerebrum:4.38 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.14 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:9.12 placenta:8.49 prostate:8.54 ovary:8.76 testis:6.43 heart:8.04 muscle:6.32 esophagus:6.90 stomach:7.87 intestine:8.28 colon:7.61 liver/hepato:5.74 lung:9.21 bladder:- kidney:8.08 pituitary:5.80 thyroid/parathyroid:8.80 adrenal gland:7.85 pancreas:7.34 breast:8.96 salivary:7.77
CAGE uterus:6.42 placenta:5.56 prostate:5.73 ovary:5.30 testis:5.15 heart:5.69 muscle:5.08 esophagus:5.13 stomach:- intestine:5.21 colon:4.59     liver/hepato:4.63    lung:5.75 bladder:5.76 kidney:6.24 pituitary:3.70 thyroid/parathyroid:5.38 adrenal gland:- pancreas:3.82 breast:5.29 salivary:5.02
RNA-seq uterus:- placenta:- prostate:6.43 ovary:5.34 testis:6.60 heart:5.47 muscle:3.51 esophagus:- stomach:- intestine:- colon:6.42     liver/hepato:2.39        lung:6.47    bladder:- kidney:8.13 pituitary:- thyroid/parathyroid:7.06 adrenal gland:6.24 pancreas:- breast:6.79 salivary:-

IDs

Refseq ID NM_001901
Gene ID 1490
Unigene ID -
Probe set ID 209101_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000118523
GTEx ID ENSG00000118523

Orthologous Gene

Mouse[1]  NM_010217
Rat[1]  NM_022266

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1293144
1334251
1654338
1925598
9054739
9242708
9371786
9927660
10204117
10350062
10457363
10614647
10809757
11101692
11502477
11532378
11697887
11744618
11751417
11818516
11855859
11897682
11967989
12016149
12036876
12114504
12150969
12217862
12218048
12239232
12297288
12398938
12470643
12477932
12496395
12535930
12553878
12571253
12595495
12668285
12760970
12787426
12811819
12831056
12888575
12941731
12951326
14512169
14574404
14585398
14633859
14684735
14702039
14758550
14988298
14996858
15003992
15039132
15041728
15045137
15053922
15090860
15111539
15113833
15135656
15247510
15298857
15345671
15377500
15459777
15526358
15536170
15598883
15703175
15761189
15761249
15820145
15857887
15940639
15941869
15950619
15956925
16044512
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16457822
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16543635
16571622
16684954
16731742
16790529
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16820572
16858645
16877704
16889607
16899928
17093396
17116388
17119035
17170128
17192487
17215322
17224075
17239539
17239853
17375628
17393107
17399683
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17437852
17441427
17498677
17550972
17579708
17580150
17602195
17622321
17657819
17671176
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17681742
17765657
17786299
17876891
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17908800
17915216
17922682
17944991
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17951996
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18029348
18080105
18172013
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18344285
18358427
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18400984
18451226
18481257
18596209
18622762
18628999
18639630
18648180
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18783549
18787533
18805993
18835464
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18846327
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19016368
19054816
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19069651
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19153601
19179545
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19453261
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19641518
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19670427
19673024
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19762080
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19789190
19822645
19850743
19861250
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19890996
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19922639
19955828
20004937
20015945
20018872
20032097
20032117
20050020
20053285
20056838
20117462
20162579
20180416
20201953
20222112
20237235
20237496
20238043
20305691
20453000
20522428
20522536
20576680
20613589
20628624
20660557
20685720
20689330
20697347
20731800
20814177
20840672
20966418
20971063
21054221
21071938
21081514
21098624
21166920
21209863
21236242
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21265091
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21352962
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21484860
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21576830
21609573
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21654839
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21771732
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21955589
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22134873
22205539
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22684333
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22814105
22846210
22906474
22918238
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23029004
23044205
23055574
23056332
23061738
23073116
23108098
23142580
23175185
23227240
23274856
23284892
23307318
23323010
23368866
23383241
23390502
23414795
23435419
23454256
23494140
23501329
23508392
23530034
23564449
23567513
23582094
23593935
23631855
23648563
23681229
23687336
23727026
23741006
23772794
23824844
23847295
23988606
24005672
24014274
24079812
24090133
24112732
24121259
24122827
24154679
24462773
24464580
24597264

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0001502  cartilage condensation
GO:0030154  cell differentiation
GO:0016477  cell migration
GO:0007160  cell-matrix adhesion
GO:0044255  cellular lipid metabolic process
GO:0060401  cytosolic calcium ion transport
GO:0006260  DNA replication
GO:0008544  epidermis development
GO:0070278  extracellular matrix constituent secretion
GO:0008543  fibroblast growth factor receptor signaling pathway
GO:0010467  gene expression
GO:0007229  integrin-mediated signaling pathway
GO:0030324  lung development
GO:0010629  negative regulation of gene expression
GO:0010260  organ senescence
GO:0001503  ossification
GO:0060452  positive regulation of cardiac muscle contraction
GO:0043280  positive regulation of caspase activity
GO:0050867  positive regulation of cell activation
GO:0010942  positive regulation of cell death
GO:0045597  positive regulation of cell differentiation
GO:0008284  positive regulation of cell proliferation
GO:0032967  positive regulation of collagen biosynthetic process
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0070318  positive regulation of G0 to G1 transition
GO:0010628  positive regulation of gene expression
GO:0046330  positive regulation of JNK cascade
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0051496  positive regulation of stress fiber formation
GO:0001558  regulation of cell growth
GO:0032330  regulation of chondrocyte differentiation
GO:0043200  response to amino acid stimulus
GO:0034059  response to anoxia
GO:0032355  response to estradiol stimulus
GO:0070542  response to fatty acid
GO:0009749  response to glucose stimulus
GO:0051385  response to mineralocorticoid stimulus
GO:0043434  response to peptide hormone stimulus
GO:0009611  response to wounding
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005938  cell cortex
GO:0005801  cis-Golgi network
GO:0005829  cytosol
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005794  Golgi apparatus
GO:0043231  intracellular membrane-bounded organelle
GO:0048471  perinuclear region of cytoplasm
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0001968  fibronectin binding
GO:0008083  growth factor activity
GO:0008201  heparin binding
GO:0005520  insulin-like growth factor binding
GO:0005178  integrin binding