connective tissue growth factor

Synonym

MGC102839, connective tissue growth factor, IGFBP8, Hypertrophic chondrocyte-specific protein 24, HCS24, CTGF, CCN2, Connective tissue growth factor precursor, NOV2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:5.53

cerebellum:4.47

brain stem:5.45

corpus callosum/glia:5.56

pineal gland:-

peripheral nerve:8.30

spine:5.86

retina:-

eye:-

artery/aorta:8.76

vein:9.66

lymphnode:6.53

peripheral blood:-

spleen:9.54

thymus:5.90

bone marrow:6.04

adipose:8.19

bone:-

skin:7.58

CAGE

cerebrum:3.60

cerebellum:-

brain stem:3.45

corpus callosum/glia:3.89

pineal gland:3.82

peripheral nerve:-

spine:3.79

retina:-

eye:-

artery/aorta:7.57

vein:5.37

lymphnode:4.99

peripheral blood:-

spleen:6.97

thymus:3.48

bone marrow:-

adipose:5.51

bone:-

skin:-

RNA-seq

cerebrum:4.38

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:5.14

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:6.01

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:9.12

placenta:8.49

prostate:8.54

ovary:8.76

testis:6.43

heart:8.04

muscle:6.32

esophagus:6.90

stomach:7.87

intestine:8.28

colon:7.61

liver/hepato:5.74

lung:9.21

bladder:-

kidney:8.08

pituitary:5.80

thyroid/parathyroid:8.80

adrenal gland:7.85

pancreas:7.34

breast:8.96

salivary:7.77

CAGE

uterus:6.42

placenta:5.56

prostate:5.73

ovary:5.30

testis:5.15

heart:5.69

muscle:5.08

esophagus:5.13

stomach:-

intestine:5.21

colon:4.59

liver/hepato:4.63

lung:5.75

bladder:5.76

kidney:6.24

pituitary:3.70

thyroid/parathyroid:5.38

adrenal gland:-

pancreas:3.82

breast:5.29

salivary:5.02

RNA-seq

uterus:-

placenta:-

prostate:6.43

ovary:5.34

testis:6.60

heart:5.47

muscle:3.51

esophagus:-

stomach:-

intestine:-

colon:6.42

liver/hepato:2.39

lung:6.47

bladder:-

kidney:8.13

pituitary:-

thyroid/parathyroid:7.06

adrenal gland:6.24

pancreas:-

breast:6.79

salivary:-

IDs

Refseq ID	NM_001901
Gene ID	1490
Unigene ID	-
Probe set ID	209101_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000118523
GTEx ID	ENSG00000118523

Orthologous Gene

Mouse[1]	NM_010217
Rat[1]	NM_022266

Chromosomal Region

6q23.2 [132,269,316 - 132,272,513]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006207	Cystine knot, C-terminal
IPR000884	Thrombospondin, type 1 repeat

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0001502	cartilage condensation
GO:0030154	cell differentiation
GO:0016477	cell migration
GO:0007160	cell-matrix adhesion
GO:0044255	cellular lipid metabolic process
GO:0060401	cytosolic calcium ion transport
GO:0006260	DNA replication
GO:0008544	epidermis development
GO:0070278	extracellular matrix constituent secretion
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0010467	gene expression
GO:0007229	integrin-mediated signaling pathway
GO:0030324	lung development
GO:0010629	negative regulation of gene expression
GO:0010260	organ senescence
GO:0001503	ossification
GO:0060452	positive regulation of cardiac muscle contraction
GO:0043280	positive regulation of caspase activity
GO:0050867	positive regulation of cell activation
GO:0010942	positive regulation of cell death
GO:0045597	positive regulation of cell differentiation
GO:0008284	positive regulation of cell proliferation
GO:0032967	positive regulation of collagen biosynthetic process
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0070318	positive regulation of G0 to G1 transition
GO:0010628	positive regulation of gene expression
GO:0046330	positive regulation of JNK cascade
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0051496	positive regulation of stress fiber formation
GO:0001558	regulation of cell growth
GO:0032330	regulation of chondrocyte differentiation
GO:0043200	response to amino acid stimulus
GO:0034059	response to anoxia
GO:0032355	response to estradiol stimulus
GO:0070542	response to fatty acid
GO:0009749	response to glucose stimulus
GO:0051385	response to mineralocorticoid stimulus
GO:0043434	response to peptide hormone stimulus
GO:0009611	response to wounding
GO:0006367	transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005938	cell cortex
GO:0005801	cis-Golgi network
GO:0005829	cytosol
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005794	Golgi apparatus
GO:0043231	intracellular membrane-bounded organelle
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane
GO:0005578	proteinaceous extracellular matrix

Molecular Function

GO:0001968	fibronectin binding
GO:0008083	growth factor activity
GO:0008201	heparin binding
GO:0005520	insulin-like growth factor binding
GO:0005178	integrin binding

connective tissue growth factor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function