adrenergic, alpha-2B-, receptor

Synonym

ADRA2L1, Alpha-2 adrenergic receptor subtype C2, ALPHA2BAR, Alpha-2B adrenoceptor, adrenergic, alpha-2B-, receptor, Alpha-2B adrenoreceptor, ADRA2B, ADRA2RL1, ADRARL1, Alpha-2B adrenergic receptor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:61.30

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.79

cerebellum:5.99

brain stem:5.79

corpus callosum/glia:5.74

pineal gland:-

peripheral nerve:5.44

spine:5.50

retina:-

eye:-

artery/aorta:5.91

vein:6.14

lymphnode:5.74

peripheral blood:-

spleen:5.59

thymus:5.54

bone marrow:5.86

adipose:5.79

bone:-

skin:5.78

CAGE

cerebrum:0.66

cerebellum:-

brain stem:1.23

corpus callosum/glia:1.29

pineal gland:0.21

peripheral nerve:-

spine:0.62

retina:-

eye:-

artery/aorta:2.46

vein:0.79

lymphnode:0.12

peripheral blood:-

spleen:1.89

thymus:0.18

bone marrow:-

adipose:1.88

bone:-

skin:-

RNA-seq

cerebrum:0.16

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.83

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.89

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.54

placenta:5.90

prostate:5.20

ovary:5.59

testis:5.26

heart:6.05

muscle:6.09

esophagus:5.78

stomach:5.61

intestine:5.77

colon:5.68

liver/hepato:5.89

lung:5.75

bladder:-

kidney:5.82

pituitary:5.63

thyroid/parathyroid:5.59

adrenal gland:5.87

pancreas:6.19

breast:5.59

salivary:6.11

CAGE

uterus:1.56

placenta:0.99

prostate:1.63

ovary:1.86

testis:1.06

heart:1.48

muscle:2.05

esophagus:1.80

stomach:-

intestine:0.77

colon:1.41

liver/hepato:2.01

lung:0.18

bladder:1.64

kidney:1.09

pituitary:0.10

thyroid/parathyroid:1.32

adrenal gland:-

pancreas:0.94

breast:2.19

salivary:0.62

RNA-seq

uterus:-

placenta:-

prostate:1.08

ovary:0.37

testis:2.11

heart:1.41

muscle:1.11

esophagus:-

stomach:-

intestine:-

colon:1.60

liver/hepato:0.81

lung:0.21

bladder:-

kidney:1.08

pituitary:-

thyroid/parathyroid:0.32

adrenal gland:1.02

pancreas:-

breast:0.46

salivary:-

IDs

Refseq ID	NM_000682
Gene ID	151
Unigene ID	Hs.247686
Probe set ID	208544_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000222040
GTEx ID	ENSG00000222040

Orthologous Gene

Mouse[1]	NM_009633
Rat[1]	NM_138505

Chromosomal Region

2q11.1 [96,778,707 - 96,781,984]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR015695	Adrenergic receptor, alpha-2A/2B/2C
IPR000207	Adrenergic receptor, alpha-2B
IPR017452	GPCR, rhodopsin-like superfamily

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0032148	activation of protein kinase B activity
GO:0001525	angiogenesis
GO:0007596	blood coagulation
GO:0007267	cell-cell signaling
GO:0007565	female pregnancy
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0000165	MAPKKK cascade
GO:0032811	negative regulation of epinephrine secretion
GO:0010700	negative regulation of norepinephrine secretion
GO:0030168	platelet activation
GO:0045777	positive regulation of blood pressure
GO:0045666	positive regulation of neuron differentiation
GO:0070474	positive regulation of uterine smooth muscle contraction
GO:0003056	regulation of vascular smooth muscle contraction

Cellular Component

GO:0005887	integral to plasma membrane
GO:0005886	plasma membrane

Molecular Function

GO:0004938	alpha2-adrenergic receptor activity
GO:0051379	epinephrine binding
GO:0005515	protein binding

adrenergic, alpha-2B-, receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function