cathepsin H

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Synonym

minichain, CPSB, ACC-5, cathepsin H, ACC-4, CTSH, DKFZp686B24257, Cathepsin H precursor, MGC1519

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:32 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:296.70 peripheral nerve:92 spine:336.90 retina:- eye:52.90 artery/aorta:30 vein:66.60 lymphnode:121.30 peripheral blood:164 spleen:37.80 thymus:25.80 bone marrow:19.70 adipose:80.70 bone:64 skin:72
GeneChip cerebrum:7.39 cerebellum:6.29 brain stem:7.14 corpus callosum/glia:8.62 pineal gland:- peripheral nerve:7.33 spine:7.83 retina:- eye:- artery/aorta:7.84 vein:7.99 lymphnode:9.48 peripheral blood:- spleen:8.21 thymus:7.82 bone marrow:7.78 adipose:8.14 bone:- skin:8.44
CAGE cerebrum:3.90 cerebellum:- brain stem:3.73 corpus callosum/glia:4.66 pineal gland:3.49 peripheral nerve:- spine:4.25 retina:- eye:- artery/aorta:4.45 vein:5.36 lymphnode:5.43 peripheral blood:- spleen:4.76 thymus:3.57 bone marrow:- adipose:4.61 bone:- skin:-
RNA-seq cerebrum:4.86 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.87 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.72 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:58.30 prostate:56.30 ovary:- testis:30.30 heart:166 muscle:40.20 esophagus:- stomach:467.30 intestine:32.40 colon:17     liver/hepato:42.20        lung:263.90    bladder:- kidney:114.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:18.60 salivary:-
GeneChip uterus:8.21 placenta:6.72 prostate:9.44 ovary:8.42 testis:6.92 heart:7.62 muscle:6.93 esophagus:7.58 stomach:8.42 intestine:8.22 colon:7.87 liver/hepato:8.21 lung:9.61 bladder:- kidney:10.32 pituitary:7.40 thyroid/parathyroid:7.79 adrenal gland:7.88 pancreas:7.44 breast:8.36 salivary:8.76
CAGE uterus:4.24 placenta:3.80 prostate:4.75 ovary:4.47 testis:3.48 heart:4.15 muscle:3.56 esophagus:3.81 stomach:- intestine:4.55 colon:4.21     liver/hepato:4.18    lung:6.37 bladder:4.40 kidney:5.89 pituitary:3.15 thyroid/parathyroid:3.85 adrenal gland:- pancreas:4.93 breast:4.99 salivary:4.64
RNA-seq uterus:- placenta:- prostate:6.42 ovary:5.91 testis:4.40 heart:4.17 muscle:3.25 esophagus:- stomach:- intestine:- colon:4.66     liver/hepato:5.21        lung:7.03    bladder:- kidney:7.17 pituitary:- thyroid/parathyroid:5.33 adrenal gland:6.75 pancreas:- breast:4.46 salivary:-

Gene Information

IDs

Refseq ID NM_004390
Gene ID 1512
Unigene ID Hs.148641
Probe set ID 202295_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000103811
GTEx ID ENSG00000103811

Orthologous Gene

Mouse[1]  NM_007801
Rat [0]  

Chromosomal Region

15q25.1  [79,213,400  -  79,241,916]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1837142
2486008
2587265
2588347
2849458
3342889
6184075
6203523
7821789
8811434
9050938
9076588
10395917
11134363
11136537
11514663
11796715
12034564
12203716
12477932
12581647
12589965
12615673
14515996
14662023
14766755
15127951
15196205
15231747
15489334
15646835
16502470
16822283
17500053
17601350
18029348
18216060
18676680
18949742
18977241
18978792
19073967
19170196
19404922
19430480
19625176
19692168
19913121
20203524
20628086
20647273
20881085
21217776
21771265
21890473
22704610
23204516
23483898
23874603

Gene Ontology  (GO ID)

Biological Process

GO:0002250  adaptive immune response
GO:0019882  antigen processing and presentation
GO:0006915  apoptosis
GO:0010815  bradykinin catabolic process
GO:0060448  dichotomous subdivision of terminal units involved in lung branching
GO:0070371  ERK1 and ERK2 cascade
GO:0002764  immune response-regulating signal transduction
GO:0033619  membrane protein proteolysis
GO:0001656  metanephros development
GO:0043066  negative regulation of apoptosis
GO:0010813  neuropeptide catabolic process
GO:0045766  positive regulation of angiogenesis
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0010634  positive regulation of epithelial cell migration
GO:0010628  positive regulation of gene expression
GO:0010952  positive regulation of peptidase activity
GO:0031648  protein destabilization
GO:0006508  proteolysis
GO:0032526  response to retinoic acid
GO:0007283  spermatogenesis
GO:0043129  surfactant homeostasis
GO:0001913  T cell mediated cytotoxicity
GO:0031638  zymogen activation

Cellular Component

GO:0001669  acrosomal vesicle
GO:0005829  cytosol
GO:0005615  extracellular space
GO:0005764  lysosome
GO:0001520  outer dense fiber

Molecular Function

GO:0004177  aminopeptidase activity
GO:0016505  apoptotic protease activator activity
GO:0004197  cysteine-type endopeptidase activity
GO:0008234  cysteine-type peptidase activity
GO:0004175  endopeptidase activity
GO:0030108  HLA-A specific activating MHC class I receptor activity
GO:0030984  kininogen binding
GO:0008233  peptidase activity
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0043621  protein self-association
GO:0004252  serine-type endopeptidase activity
GO:0070324  thyroid hormone binding