growth differentiation factor 7

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Synonym

Growth/differentiation factor 7 precursor, GDF-7, GDF7, growth differentiation factor 7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:1.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0.03 cerebellum:- brain stem:0.50 corpus callosum/glia:0.13 pineal gland:0.36 peripheral nerve:- spine:0.23 retina:- eye:- artery/aorta:1.48 vein:0.18 lymphnode:0.84 peripheral blood:- spleen:0.76 thymus:0.06 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.03 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.25 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:1.31 placenta:0.30 prostate:0.58 ovary:0.07 testis:0 heart:0.20 muscle:0 esophagus:0.33 stomach:- intestine:0 colon:0.04     liver/hepato:0.46    lung:0.17 bladder:0.53 kidney:0.67 pituitary:0 thyroid/parathyroid:0.06 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.09 ovary:0.02 testis:0.08 heart:0.04 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0.29        lung:0.03    bladder:- kidney:0.14 pituitary:- thyroid/parathyroid:0.01 adrenal gland:0.25 pancreas:- breast:0.02 salivary:-

Gene Information

IDs

Refseq ID NM_182828
Gene ID 151449
Unigene ID Hs.447688
Probe set ID -
Ensembl ID ENSG00000143869
GTEx ID ENSG00000143869

Orthologous Gene

Mouse[1]  NM_013527
Rat [0]  

Chromosomal Region

2p24.1  [20,866,424  -  20,873,418]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9808626
10022976
12741987
16049014
20102312
20237496
20334610
20339536
20677014
20734064
21702718
24155967

Gene Ontology  (GO ID)

Biological Process

GO:0032924  activin receptor signaling pathway
GO:0007411  axon guidance
GO:0030509  BMP signaling pathway
GO:0048754  branching morphogenesis of a tube
GO:0045165  cell fate commitment
GO:0030855  epithelial cell differentiation
GO:0048853  forebrain morphogenesis
GO:0022612  gland morphogenesis
GO:0040007  growth
GO:0030901  midbrain development
GO:0060571  morphogenesis of an epithelial fold
GO:0060389  pathway-restricted SMAD protein phosphorylation
GO:0045666  positive regulation of neuron differentiation
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0048608  reproductive structure development
GO:0021509  roof plate formation
GO:0021527  spinal cord association neuron differentiation

Cellular Component

GO:0005615  extracellular space

Molecular Function

GO:0005125  cytokine activity
GO:0008083  growth factor activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity