adrenergic, alpha-2C-, receptor

Synonym

ADRARL2, adrenergic, alpha-2C-, receptor, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, ADRA2L2, ADRA2C, ADRA2RL2, Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, ALPHA2CAR

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:5.90

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:5.93

cerebellum:6.10

brain stem:5.69

corpus callosum/glia:5.74

pineal gland:-

peripheral nerve:5.44

spine:5.25

retina:-

eye:-

artery/aorta:6.34

vein:6.84

lymphnode:5.66

peripheral blood:-

spleen:5.72

thymus:5.02

bone marrow:5.79

adipose:5.74

bone:-

skin:5.58

CAGE

cerebrum:0.68

cerebellum:-

brain stem:0.57

corpus callosum/glia:0.47

pineal gland:0

peripheral nerve:-

spine:0.61

retina:-

eye:-

artery/aorta:3.86

vein:1.80

lymphnode:0.41

peripheral blood:-

spleen:1.72

thymus:0.12

bone marrow:-

adipose:1.95

bone:-

skin:-

RNA-seq

cerebrum:0.68

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.84

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.70

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:21.90

prostate:-

ovary:-

testis:-

heart:12.80

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:4.90

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:-

salivary:-

GeneChip

uterus:6.59

placenta:5.93

prostate:5.53

ovary:6.04

testis:5.33

heart:6.15

muscle:5.62

esophagus:5.52

stomach:5.49

intestine:5.90

colon:6.02

liver/hepato:5.60

lung:5.89

bladder:-

kidney:6.13

pituitary:5.33

thyroid/parathyroid:5.04

adrenal gland:5.78

pancreas:6.15

breast:5.79

salivary:5.72

CAGE

uterus:2.71

placenta:3.17

prostate:1.48

ovary:1.98

testis:1.52

heart:1.60

muscle:0.67

esophagus:1.01

stomach:-

intestine:0.57

colon:0.97

liver/hepato:0.71

lung:0.78

bladder:1.09

kidney:2.12

pituitary:1.05

thyroid/parathyroid:0.57

adrenal gland:-

pancreas:0.58

breast:2.34

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:1.91

ovary:1.73

testis:3.23

heart:1.30

muscle:0.74

esophagus:-

stomach:-

intestine:-

colon:1.73

liver/hepato:0.16

lung:1.16

bladder:-

kidney:3.07

pituitary:-

thyroid/parathyroid:0.82

adrenal gland:2.61

pancreas:-

breast:1.88

salivary:-

IDs

Refseq ID	NM_000683
Gene ID	152
Unigene ID	Hs.123022
Probe set ID	206128_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000184160
GTEx ID	ENSG00000184160

Orthologous Gene

Mouse[2]	NM_007418
Rat [0]

Chromosomal Region

4p16.3 [3,768,075 - 3,770,251]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR015695	Adrenergic receptor, alpha-2A/2B/2C
IPR000735	Adrenergic receptor, alpha-2C
IPR017452	GPCR, rhodopsin-like superfamily

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0032148	activation of protein kinase B activity
GO:0007596	blood coagulation
GO:0007267	cell-cell signaling
GO:0006112	energy reserve metabolic process
GO:0007565	female pregnancy
GO:0007186	G-protein coupled receptor protein signaling pathway
GO:0032811	negative regulation of epinephrine secretion
GO:0010700	negative regulation of norepinephrine secretion
GO:0070473	negative regulation of uterine smooth muscle contraction
GO:0030168	platelet activation
GO:0045666	positive regulation of neuron differentiation
GO:0045907	positive regulation of vasoconstriction
GO:0050796	regulation of insulin secretion
GO:0051930	regulation of sensory perception of pain

Cellular Component

GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005887	integral to plasma membrane
GO:0043679	nerve terminal
GO:0005886	plasma membrane

Molecular Function

GO:0031694	alpha-2A adrenergic receptor binding
GO:0004938	alpha2-adrenergic receptor activity
GO:0051379	epinephrine binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity

adrenergic, alpha-2C-, receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function