adrenergic, beta-1-, receptor

Synonym

Beta-1 adrenoceptor, Beta-1 adrenergic receptor, ADRB1, ADRB1R, RHR, Beta-1 adrenoreceptor, adrenergic, beta-1-, receptor, B1AR, BETA1AR

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:593.40

peripheral nerve:-

spine:-

retina:-

eye:11.80

artery/aorta:-

vein:-

lymphnode:20.20

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:3.69

cerebellum:3.61

brain stem:3.64

corpus callosum/glia:3.44

pineal gland:-

peripheral nerve:3.27

spine:3.34

retina:-

eye:-

artery/aorta:3.46

vein:3.64

lymphnode:3.39

peripheral blood:-

spleen:3.20

thymus:3.12

bone marrow:3.34

adipose:3.64

bone:-

skin:3.71

CAGE

cerebrum:3.09

cerebellum:-

brain stem:1.97

corpus callosum/glia:1.92

pineal gland:6.32

peripheral nerve:-

spine:2.13

retina:-

eye:-

artery/aorta:1.85

vein:2.60

lymphnode:1.19

peripheral blood:-

spleen:1.79

thymus:0.57

bone marrow:-

adipose:2.54

bone:-

skin:-

RNA-seq

cerebrum:2.39

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.27

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.97

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:21.90

prostate:-

ovary:-

testis:4.30

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:3.26

placenta:4.70

prostate:3.54

ovary:3.40

testis:3.26

heart:4.28

muscle:3.55

esophagus:3.28

stomach:3.29

intestine:3.48

colon:3.40

liver/hepato:3.31

lung:4.26

bladder:-

kidney:3.38

pituitary:3.30

thyroid/parathyroid:3.13

adrenal gland:3.23

pancreas:3.85

breast:3.31

salivary:3.57

CAGE

uterus:0.44

placenta:4.98

prostate:2.98

ovary:0.47

testis:0.66

heart:4.56

muscle:0.34

esophagus:1.44

stomach:-

intestine:1.77

colon:1.74

liver/hepato:0.46

lung:4.15

bladder:1.45

kidney:1.40

pituitary:0.58

thyroid/parathyroid:0.64

adrenal gland:-

pancreas:1.74

breast:3.22

salivary:3.22

RNA-seq

uterus:-

placenta:-

prostate:1.22

ovary:0.09

testis:0.29

heart:3.20

muscle:0.13

esophagus:-

stomach:-

intestine:-

colon:0.76

liver/hepato:0.12

lung:2.74

bladder:-

kidney:0.72

pituitary:-

thyroid/parathyroid:0.35

adrenal gland:0.37

pancreas:-

breast:3.03

salivary:-

IDs

Refseq ID	NM_000684
Gene ID	153
Unigene ID	Hs.99913
Probe set ID	208214_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000043591
GTEx ID	ENSG00000043591

Orthologous Gene

Mouse[1]	NM_007419
Rat[1]	NM_012701

Chromosomal Region

10q25.3 [115,803,806 - 115,806,667]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002232	5-Hydroxytryptamine 6 receptor
IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR000507	Adrenergic receptor, beta 1
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007568	aging
GO:0006915	apoptosis
GO:0050873	brown fat cell differentiation
GO:0002024	diet induced thermogenesis
GO:0042596	fear response
GO:0005980	glycogen catabolic process
GO:0031649	heat generation
GO:0055088	lipid homeostasis
GO:0007613	memory
GO:0040015	negative regulation of multicellular organism growth
GO:0045986	negative regulation of smooth muscle contraction
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0043950	positive regulation of cAMP-mediated signaling
GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine
GO:0032320	positive regulation of Ras GTPase activity
GO:0046878	positive regulation of saliva secretion
GO:0003084	positive regulation of systemic arterial blood pressure
GO:0003061	positive regulation of the force of heart contraction by norepinephrine
GO:0033365	protein localization in organelle
GO:0051924	regulation of calcium ion transport
GO:0060080	regulation of inhibitory postsynaptic membrane potential
GO:0009409	response to cold
GO:0007266	Rho protein signal transduction
GO:0019233	sensory perception of pain
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0042060	wound healing

Cellular Component

GO:0005737	cytoplasm
GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0031694	alpha-2A adrenergic receptor binding
GO:0004939	beta-adrenergic receptor activity
GO:0004940	beta1-adrenergic receptor activity
GO:0035240	dopamine binding
GO:0008144	drug binding
GO:0051379	epinephrine binding
GO:0051380	norepinephrine binding
GO:0030165	PDZ domain binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0005088	Ras guanyl-nucleotide exchange factor activity
GO:0005057	receptor signaling protein activity

adrenergic, beta-1-, receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function