NK2 transcription factor related, locus 3 (Drosophila)

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Synonym

NKX2-3, Homeobox protein Nkx-2.3, NKX23, NKX2C, NKX2.3, Homeobox protein NKX-2.3, NK-2 (Drosophila) homolog C, Homeobox protein NK-2 homolog C

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:56.70 thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:0 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.34 vein:0 lymphnode:1.03 peripheral blood:- spleen:3.55 thymus:0.12 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.12 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:388.80 colon:8.50     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:0.16 placenta:0 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0.33 stomach:- intestine:2.88 colon:3.19     liver/hepato:0.14    lung:0 bladder:0.09 kidney:0 pituitary:0 thyroid/parathyroid:0.17 adrenal gland:- pancreas:1.87 breast:0 salivary:0.62
RNA-seq uterus:- placenta:- prostate:0.05 ovary:0.01 testis:0.17 heart:0.01 muscle:0 esophagus:- stomach:- intestine:- colon:3.51     liver/hepato:0.01        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.29 adrenal gland:0.02 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_145285
Gene ID 159296
Unigene ID Hs.243272
Probe set ID -
Ensembl ID ENSG00000119919
GTEx ID ENSG00000119919

Orthologous Gene

Mouse[2]  NM_008699
Rat[1]  NM_001107594

Chromosomal Region

10q24.2  [101,292,690  -  101,296,278]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

8812123
11457859
12141427
12477932
15164054
15489334
16385451
17554261
17554300
18255255
18438405
18438406
18587394
18936107
19174780
19422935
19683022
19760754
19861958
20165982
20188614
20211142
20228798
20228799
20473688
20886065
21049557
21072187
21102463
21514341
21637825
21803625
21968973
22377701
22412388
23064961
23128233
23222517

Gene Ontology  (GO ID)

Biological Process

GO:0008150  biological_process
GO:0043367  CD4-positive, alpha beta T cell differentiation
GO:0022612  gland morphogenesis
GO:0001776  leukocyte homeostasis
GO:0050900  leukocyte migration
GO:0048535  lymph node development
GO:0030225  macrophage differentiation
GO:0042475  odontogenesis of dentine-containing tooth
GO:0048541  Peyer's patch development
GO:0002317  plasma cell differentiation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0048621  post-embryonic gut morphogenesis
GO:0042127  regulation of cell proliferation
GO:0048536  spleen development
GO:0006351  transcription, DNA-dependent
GO:0006641  triglyceride metabolic process

Cellular Component

GO:0005575  cellular_component
GO:0005634  nucleus

Molecular Function

GO:0003674  molecular_function
GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity