dystroglycan 1 (dystrophin-associated glycoprotein 1)

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Synonym

DAG1, A3a, DAG, Dystroglycan precursor, AGRNR, Dystrophin-associated glycoprotein 1, 156DAG

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:83

cerebellum:138.50

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:61.30

spine:112.30

retina:-

eye:82.30

artery/aorta:119.90

vein:133.30

lymphnode:20.20

peripheral blood:18.20

spleen:18.90

thymus:-

bone marrow:19.70

adipose:121

bone:51.20

skin:115.20

GeneChip

cerebrum:7.82

cerebellum:7.70

brain stem:7.77

corpus callosum/glia:7.98

pineal gland:-

peripheral nerve:9.65

spine:8.19

retina:-

eye:-

artery/aorta:8.55

vein:8.76

lymphnode:7.32

peripheral blood:-

spleen:7.34

thymus:6.73

bone marrow:6.26

adipose:8.02

bone:-

skin:8.36

CAGE

cerebrum:3.96

cerebellum:-

brain stem:3.94

corpus callosum/glia:4.34

pineal gland:3.46

peripheral nerve:-

spine:3.91

retina:-

eye:-

artery/aorta:4.63

vein:3.53

lymphnode:3.44

peripheral blood:-

spleen:3.05

thymus:2.87

bone marrow:-

adipose:4.13

bone:-

skin:-

RNA-seq

cerebrum:0.36

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.52

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.47

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:109.40

placenta:167.60

prostate:180.20

ovary:37.30

testis:103.80

heart:102.20

muscle:241.10

esophagus:-

stomach:42.50

intestine:-

colon:76.30

liver/hepato:31.70

lung:107.50

bladder:-

kidney:176.80

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:53.30

breast:83.60

salivary:-

GeneChip

uterus:8.28

placenta:9.41

prostate:8.42

ovary:8.51

testis:8.55

heart:8.58

muscle:9.24

esophagus:8.41

stomach:8.52

intestine:8.69

colon:8.66

liver/hepato:8.24

lung:8.32

bladder:-

kidney:8.56

pituitary:7.98

thyroid/parathyroid:8.10

adrenal gland:7.84

pancreas:8.30

breast:8.84

salivary:8.15

CAGE

uterus:3.97

placenta:4.84

prostate:3.78

ovary:4.25

testis:4.56

heart:4.25

muscle:4.53

esophagus:4.09

stomach:-

intestine:3.99

colon:3.98

liver/hepato:4.42

lung:3.83

bladder:4.12

kidney:4.22

pituitary:3.91

thyroid/parathyroid:3.71

adrenal gland:-

pancreas:4.41

breast:3.90

salivary:3.98

RNA-seq

uterus:-

placenta:-

prostate:1.78

ovary:2.28

testis:1.76

heart:2.63

muscle:3.29

esophagus:-

stomach:-

intestine:-

colon:0.38

liver/hepato:0.71

lung:1.54

bladder:-

kidney:0.34

pituitary:-

thyroid/parathyroid:1.69

adrenal gland:0.68

pancreas:-

breast:1.94

salivary:-

IDs

Refseq ID	NM_004393
Gene ID	1605
Unigene ID	Hs.76111
Probe set ID	205417_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000173402
GTEx ID	ENSG00000173402

Orthologous Gene

Mouse[8]	NM_010017
Rat[8]	NM_010017

Chromosomal Region

3p21.31 [49,506,146 - 49,573,048]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR015919	Cadherin-like
IPR006644	Dystroglycan-type cadherin-like

Gene Ontology (GO ID)

Biological Process

GO:0060441	branching involved in lung morphogenesis
GO:0060445	branching involved in salivary gland morphogenesis
GO:0007016	cytoskeletal anchoring at plasma membrane
GO:0030198	extracellular matrix organization
GO:0006509	membrane protein ectodomain proteolysis
GO:0034453	microtubule anchoring
GO:0002011	morphogenesis of an epithelial sheet
GO:0022011	myelination in the peripheral nervous system
GO:0030336	negative regulation of cell migration
GO:0043409	negative regulation of MAPKKK cascade
GO:0051898	negative regulation of protein kinase B signaling cascade
GO:0021682	nerve maturation
GO:0006607	NLS-bearing substrate import into nucleus
GO:0019048	virus-host interaction

Cellular Component

GO:0005604	basement membrane
GO:0009279	cell outer membrane
GO:0070938	contractile ring
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0016011	dystroglycan complex
GO:0016010	dystrophin-associated glycoprotein complex
GO:0005615	extracellular space
GO:0030175	filopodium
GO:0005925	focal adhesion
GO:0016021	integral to membrane
GO:0030027	lamellipodium
GO:0045121	membrane raft
GO:0033268	node of Ranvier
GO:0005654	nucleoplasm
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane
GO:0042383	sarcolemma

Molecular Function

GO:0003779	actin binding
GO:0051393	alpha-actinin binding
GO:0005509	calcium ion binding
GO:0043237	laminin-1 binding
GO:0005515	protein binding
GO:0042169	SH2 domain binding
GO:0008307	structural constituent of muscle
GO:0015631	tubulin binding
GO:0017166	vinculin binding

dystroglycan 1 (dystrophin-associated glycoprotein 1)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function