ADAM metallopeptidase with thrombospondin type 1 motif, 18

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Synonym

ADAM-TS 18, ADAMTS21, ADAMTS18, ADAM-TS18, ADAMTS-18 precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:13 cerebellum:113.30 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:237.30 eye:35.30 artery/aorta:- vein:66.60 lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:1.13 cerebellum:- brain stem:1.06 corpus callosum/glia:1.62 pineal gland:0.51 peripheral nerve:- spine:0.87 retina:- eye:- artery/aorta:0.34 vein:1.34 lymphnode:0.09 peripheral blood:- spleen:0 thymus:0.33 bone marrow:- adipose:3.23 bone:- skin:-
RNA-seq cerebrum:1.74 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.08 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.73 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:36.40 prostate:- ovary:- testis:13 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:25.40     liver/hepato:-        lung:14.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:1.39 placenta:2.11 prostate:0.27 ovary:0 testis:0.31 heart:0.13 muscle:0.05 esophagus:0 stomach:- intestine:0 colon:0.15     liver/hepato:0    lung:0 bladder:0.18 kidney:0.15 pituitary:0.99 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:1.80 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.24 ovary:0.10 testis:0.13 heart:0.02 muscle:0.02 esophagus:- stomach:- intestine:- colon:1.22     liver/hepato:0.00        lung:0.01    bladder:- kidney:0.09 pituitary:- thyroid/parathyroid:0.04 adrenal gland:0.18 pancreas:- breast:0.78 salivary:-

Gene Information

IDs

Refseq ID NM_199355
Gene ID 170692
Unigene ID Hs.188746
Probe set ID -
Ensembl ID ENSG00000140873
GTEx ID ENSG00000140873

Orthologous Gene

Mouse[1]  NM_172466
Rat [0]  

Chromosomal Region

16q23.1  [77,316,025  -  77,469,011]

Gene Family (Interpro ID)

IPR000884  Thrombospondin, type 1 repeat

Link to Pubmed  (Pubmed ID)

8889548
11867212
12477932
14702039
15489334
16507336
17546048
18398821
19218546
19249006
19806480
19844255
20164292
20379614
21047771
21862674
22425255
23356391
23648065
23818446

Gene Ontology  (GO ID)

Biological Process

GO:0006508  proteolysis

Cellular Component

GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0004222  metalloendopeptidase activity
GO:0008270  zinc ion binding