dystrophin

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Synonym

Dystrophin, DXS272, DXS269, DXS230, includes DXS142, DXS268, DXS270, DXS239, DXS142, CMD3B, DMD, DXS206, DXS164, BMD

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:109

cerebellum:88.20

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:429.40

spine:673.80

retina:711.80

eye:199.80

artery/aorta:-

vein:-

lymphnode:30.30

peripheral blood:-

spleen:94.50

thymus:25.80

bone marrow:-

adipose:161.30

bone:25.60

skin:91.20

GeneChip

cerebrum:6.51

cerebellum:6

brain stem:6.16

corpus callosum/glia:6.50

pineal gland:-

peripheral nerve:9.26

spine:6.71

retina:-

eye:-

artery/aorta:7.51

vein:8.08

lymphnode:4.94

peripheral blood:-

spleen:3.71

thymus:4.22

bone marrow:4.18

adipose:6.98

bone:-

skin:6.55

CAGE

cerebrum:3.98

cerebellum:-

brain stem:4.01

corpus callosum/glia:3.83

pineal gland:4.90

peripheral nerve:-

spine:3.91

retina:-

eye:-

artery/aorta:4.64

vein:3.55

lymphnode:2.58

peripheral blood:-

spleen:2.20

thymus:1.62

bone marrow:-

adipose:4.85

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:100.20

placenta:65.60

prostate:146.40

ovary:149.10

testis:77.90

heart:153.30

muscle:522.40

esophagus:-

stomach:127.50

intestine:97.20

colon:76.30

liver/hepato:126.70

lung:83.10

bladder:-

kidney:31.20

pituitary:116

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:106.70

breast:27.90

salivary:-

GeneChip

uterus:7

placenta:6.23

prostate:7.26

ovary:7.76

testis:5.14

heart:8.07

muscle:9.19

esophagus:6.22

stomach:7.28

intestine:7.66

colon:6.22

liver/hepato:7.76

lung:5.36

bladder:-

kidney:4.97

pituitary:5.41

thyroid/parathyroid:6.07

adrenal gland:7.14

pancreas:7.35

breast:7.03

salivary:7.88

CAGE

uterus:4.96

placenta:3.14

prostate:4.60

ovary:4.30

testis:3.29

heart:4.77

muscle:5.53

esophagus:4.43

stomach:-

intestine:3.59

colon:4.20

liver/hepato:3.90

lung:3.42

bladder:5.30

kidney:2.87

pituitary:3.20

thyroid/parathyroid:3.45

adrenal gland:-

pancreas:4.53

breast:3.97

salivary:4.68

RNA-seq

uterus:-

placenta:-

prostate:0.15

ovary:0.00

testis:0.20

heart:0.18

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.11

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_004009
Gene ID	1756
Unigene ID	Hs.495912
Probe set ID	203881_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000198947
GTEx ID	ENSG00000198947

Orthologous Gene

Mouse[4]	NM_007868
Rat [0]

Chromosomal Region

Xp21.1 [31,132,808 - 33,357,558]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016146	Calponin-homology
IPR001715	Calponin-like actin-binding
IPR018159	Spectrin/alpha-actinin
IPR001202	WW/Rsp5/WWP

Gene Ontology (GO ID)

Biological Process

GO:0060048	cardiac muscle contraction
GO:0043623	cellular protein complex assembly
GO:0034613	cellular protein localization
GO:0008065	establishment of blood-nerve barrier
GO:0060857	establishment of glial blood-brain barrier
GO:0030198	extracellular matrix organization
GO:0048747	muscle fiber development
GO:0030049	muscle filament sliding
GO:0046716	muscle homeostasis
GO:0007517	muscle organ development
GO:0014904	myotube cell development
GO:0033137	negative regulation of peptidyl-serine phosphorylation
GO:0045213	neurotransmitter receptor metabolic process
GO:0051647	nucleus localization
GO:0021629	olfactory nerve structural organization
GO:0043043	peptide biosynthetic process
GO:0001954	positive regulation of cell-matrix adhesion
GO:0045666	positive regulation of neuron differentiation
GO:0010976	positive regulation of neuron projection development
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0002027	regulation of heart rate
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity
GO:0014819	regulation of skeletal muscle contraction
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0006355	regulation of transcription, DNA-dependent

Cellular Component

GO:0015629	actin cytoskeleton
GO:0009986	cell surface
GO:0030055	cell-substrate junction
GO:0043034	costamere
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0016010	dystrophin-associated glycoprotein complex
GO:0030175	filopodium
GO:0016328	lateral plasma membrane
GO:0045121	membrane raft
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0045211	postsynaptic membrane
GO:0043234	protein complex
GO:0042383	sarcolemma
GO:0016013	syntrophin complex
GO:0030018	Z disc

Molecular Function

GO:0003779	actin binding
GO:0005509	calcium ion binding
GO:0017022	myosin binding
GO:0050998	nitric-oxide synthase binding
GO:0005515	protein binding
GO:0005200	structural constituent of cytoskeleton
GO:0008307	structural constituent of muscle
GO:0017166	vinculin binding
GO:0008270	zinc ion binding

dystrophin

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function