dedicator of cytokinesis 3

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Synonym

DOCK3, Presenilin-binding protein, Modifier of cell adhesion, Dedicator of cytokinesis protein 3, PBP protein, MOCA, KIAA0299, dedicator of cytokinesis 3, dedicator of cyto-kinesis 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:80.60 cerebellum:25.20 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:- retina:118.60 eye:29.40 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:7.15 cerebellum:7.04 brain stem:6.71 corpus callosum/glia:6.67 pineal gland:- peripheral nerve:5.96 spine:6.34 retina:- eye:- artery/aorta:4.19 vein:4.99 lymphnode:4.55 peripheral blood:- spleen:4.01 thymus:3.93 bone marrow:4.28 adipose:4.38 bone:- skin:4.51
CAGE cerebrum:1.95 cerebellum:- brain stem:1.77 corpus callosum/glia:1.81 pineal gland:1.15 peripheral nerve:- spine:1.60 retina:- eye:- artery/aorta:0.18 vein:0 lymphnode:0.06 peripheral blood:- spleen:0.09 thymus:0 bone marrow:- adipose:0.46 bone:- skin:-
RNA-seq cerebrum:3.92 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.34 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.17 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:- prostate:33.80 ovary:37.30 testis:34.60 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:37.20 salivary:-
GeneChip uterus:4.16 placenta:4.55 prostate:4.27 ovary:4.08 testis:5.49 heart:4.53 muscle:4.27 esophagus:4.65 stomach:4.40 intestine:4.18 colon:4.28 liver/hepato:4.28 lung:3.98 bladder:- kidney:4.04 pituitary:5.57 thyroid/parathyroid:6.13 adrenal gland:5.14 pancreas:4.74 breast:3.99 salivary:4.56
CAGE uterus:0.30 placenta:0 prostate:0.08 ovary:0.07 testis:0.29 heart:0.40 muscle:0.21 esophagus:0.40 stomach:- intestine:0.14 colon:0.53     liver/hepato:0    lung:0.56 bladder:0.18 kidney:0 pituitary:1.38 thyroid/parathyroid:0.95 adrenal gland:- pancreas:0 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.95 ovary:0.23 testis:1.40 heart:1.15 muscle:0.47 esophagus:- stomach:- intestine:- colon:0.69     liver/hepato:0.00        lung:0.20    bladder:- kidney:0.32 pituitary:- thyroid/parathyroid:2.12 adrenal gland:0.33 pancreas:- breast:0.34 salivary:-

Gene Information

IDs

Refseq ID NM_004947
Gene ID 1795
Unigene ID Hs.476284
Probe set ID 213482_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000088538
GTEx ID ENSG00000088538

Orthologous Gene

Mouse[1]  NM_153413
Rat[1]  NM_153413

Chromosomal Region

3p21.2  [50,712,672  -  51,421,629]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9205841
10854253
11696419
12093789
12432077
12477932
14569117
15647471
15840729
17474147
18029348
18716063
19058789
19352218
20032819
20307617
20368433
20379614
20881960
21139048
22115042
22745667
22746061
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0005085  guanyl-nucleotide exchange factor activity
GO:0005515  protein binding
GO:0017124  SH3 domain binding