jagged 1 (Alagille syndrome)

Synonym

HJ1, JAGL1, jagged 1 (Alagille syndrome), hJ1, CD339, MGC104644, AGS, AHD, JAG1, Jagged1, CD339 antigen, AWS, Jagged-1 precursor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:4.70

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:98.40

adipose:-

bone:-

skin:-

GeneChip

cerebrum:6.06

cerebellum:4.47

brain stem:6.02

corpus callosum/glia:5.82

pineal gland:-

peripheral nerve:9.44

spine:6.45

retina:-

eye:-

artery/aorta:9.70

vein:9.16

lymphnode:7.88

peripheral blood:-

spleen:8.83

thymus:7.40

bone marrow:5.56

adipose:8.74

bone:-

skin:9.49

CAGE

cerebrum:2.71

cerebellum:-

brain stem:2.71

corpus callosum/glia:2.67

pineal gland:3.03

peripheral nerve:-

spine:3.37

retina:-

eye:-

artery/aorta:5.50

vein:4.07

lymphnode:3.74

peripheral blood:-

spleen:3.72

thymus:1.68

bone marrow:-

adipose:4.10

bone:-

skin:-

RNA-seq

cerebrum:2.23

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.90

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.61

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:18.20

placenta:10.90

prostate:-

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:25.40

liver/hepato:-

lung:29.30

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:17.80

breast:9.30

salivary:-

GeneChip

uterus:9.17

placenta:8.72

prostate:9.39

ovary:8.75

testis:5.89

heart:8.31

muscle:7.08

esophagus:9.35

stomach:8.50

intestine:7.89

colon:8.12

liver/hepato:6.20

lung:8.48

bladder:-

kidney:8.60

pituitary:6.62

thyroid/parathyroid:8.28

adrenal gland:7.40

pancreas:7.25

breast:9.08

salivary:5.95

CAGE

uterus:4.54

placenta:4.11

prostate:4.06

ovary:3.70

testis:3.21

heart:4.41

muscle:3.66

esophagus:4.47

stomach:-

intestine:3.53

colon:4.38

liver/hepato:2.22

lung:4.22

bladder:3.99

kidney:3.62

pituitary:3.02

thyroid/parathyroid:3.71

adrenal gland:-

pancreas:4.11

breast:5.13

salivary:2.39

RNA-seq

uterus:-

placenta:-

prostate:4.43

ovary:3.67

testis:3.77

heart:2.71

muscle:2.43

esophagus:-

stomach:-

intestine:-

colon:4.56

liver/hepato:1.25

lung:4.59

bladder:-

kidney:3.87

pituitary:-

thyroid/parathyroid:3.54

adrenal gland:4.08

pancreas:-

breast:4.14

salivary:-

IDs

Refseq ID	NM_000214
Gene ID	182
Unigene ID	Hs.224012
Probe set ID	216268_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000101384
GTEx ID	ENSG00000101384

Orthologous Gene

Mouse[2]	NM_013822
Rat [0]

Chromosomal Region

20p12.2 [10,618,332 - 10,654,608]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001881	EGF-like calcium-binding
IPR000742	EGF-like, type 3

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0042491	auditory receptor cell differentiation
GO:0003215	cardiac right ventricle morphogenesis
GO:0060411	cardiac septum morphogenesis
GO:0001709	cell fate determination
GO:0045446	endothelial cell differentiation
GO:0030097	hemopoiesis
GO:0030216	keratinocyte differentiation
GO:0002011	morphogenesis of an epithelial sheet
GO:0007275	multicellular organismal development
GO:0045445	myoblast differentiation
GO:0045599	negative regulation of fat cell differentiation
GO:0045665	negative regulation of neuron differentiation
GO:0007399	nervous system development
GO:0007220	Notch receptor processing
GO:0007219	Notch signaling pathway
GO:0045639	positive regulation of myeloid cell differentiation
GO:0045747	positive regulation of Notch signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0003184	pulmonary valve morphogenesis
GO:0030334	regulation of cell migration
GO:0042127	regulation of cell proliferation
GO:0032495	response to muramyl dipeptide

Cellular Component

GO:0045177	apical part of cell
GO:0005576	extracellular region
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005509	calcium ion binding
GO:0008083	growth factor activity
GO:0005112	Notch binding
GO:0005198	structural molecule activity

jagged 1 (Alagille syndrome)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function