deltex homolog 1 (Drosophila)

 jump to detail

Synonym

hDTX1, Deltex-1, DTX1, Deltex1, hDx-1, deltex homolog 1 (Drosophila), Protein deltex-1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:47 artery/aorta:- vein:- lymphnode:141.50 peripheral blood:18.20 spleen:56.70 thymus:- bone marrow:- adipose:40.30 bone:- skin:4.80
GeneChip nodata
CAGE cerebrum:2.92 cerebellum:- brain stem:2.14 corpus callosum/glia:2.46 pineal gland:2.10 peripheral nerve:- spine:2.24 retina:- eye:- artery/aorta:1.22 vein:2.85 lymphnode:2.96 peripheral blood:- spleen:3.50 thymus:1.26 bone marrow:- adipose:3.10 bone:- skin:-
RNA-seq cerebrum:2.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.47 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.41 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:14.60 prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:9.80    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:1.38 placenta:0.85 prostate:1.53 ovary:1.41 testis:2.06 heart:1.14 muscle:1.23 esophagus:1.14 stomach:- intestine:1.58 colon:1.99     liver/hepato:3.58    lung:0.80 bladder:1.32 kidney:1.42 pituitary:0.99 thyroid/parathyroid:1.52 adrenal gland:- pancreas:1.74 breast:2.11 salivary:1.58
RNA-seq uterus:- placenta:- prostate:0.76 ovary:1.19 testis:2.55 heart:0.22 muscle:0.57 esophagus:- stomach:- intestine:- colon:0.85     liver/hepato:3.20        lung:0.81    bladder:- kidney:1.32 pituitary:- thyroid/parathyroid:1.87 adrenal gland:3.94 pancreas:- breast:3.79 salivary:-

Gene Information

IDs

Refseq ID NM_004416
Gene ID 1840
Unigene ID Hs.372152
Probe set ID -
Ensembl ID ENSG00000135144
GTEx ID ENSG00000135144

Orthologous Gene

Mouse[1]  NM_008052
Rat[1]  NM_008052

Chromosomal Region

12q24.13  [113,494,514  -  113,535,833]

Gene Family (Interpro ID)

IPR004170  WWE domain
IPR018123  WWE domain, subgroup

Link to Pubmed  (Pubmed ID)

7671825
9244302
9590294
11153911
11226752
11564735
11869684
12477932
12617994
12670957
12753744
15489334
15684388
17028573
17474147
18628966
19592273
19690564
20208568
21124883
21139048
21988832
22589738
23395680

Gene Ontology  (GO ID)

Biological Process

GO:0007166  cell surface receptor linked signal transduction
GO:0010001  glial cell differentiation
GO:0045665  negative regulation of neuron differentiation
GO:0045581  negative regulation of T cell differentiation
GO:0007219  Notch signaling pathway
GO:0016567  protein ubiquitination
GO:0008593  regulation of Notch signaling pathway
GO:0006366  transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0016874  ligase activity
GO:0005112  Notch binding
GO:0005515  protein binding
GO:0017124  SH3 domain binding
GO:0003713  transcription coactivator activity
GO:0031625  ubiquitin protein ligase binding
GO:0008270  zinc ion binding