nuclear receptor subfamily 0, group B, member 1

Synonym

nuclear receptor subfamily 0, group B, member 1, Nuclear receptor DAX-1, AHC, AHCH, GTD, DAX1, DAX-1, dosage-sensitive sex reversal, Nuclear receptor 0B1, NR0B1, NROB1, AHX, HHG

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:4.80

GeneChip

cerebrum:4.04

cerebellum:4.08

brain stem:3.99

corpus callosum/glia:4.19

pineal gland:-

peripheral nerve:3.63

spine:3.97

retina:-

eye:-

artery/aorta:3.88

vein:4.13

lymphnode:4.25

peripheral blood:-

spleen:3.68

thymus:3.53

bone marrow:3.71

adipose:3.88

bone:-

skin:4

CAGE

cerebrum:0.20

cerebellum:-

brain stem:0.28

corpus callosum/glia:0.79

pineal gland:0.21

peripheral nerve:-

spine:0.23

retina:-

eye:-

artery/aorta:0.34

vein:0

lymphnode:0

peripheral blood:-

spleen:0

thymus:0.06

bone marrow:-

adipose:0.14

bone:-

skin:-

RNA-seq

cerebrum:0.11

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.06

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:21.60

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:8.50

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:50.80

pancreas:88.90

breast:-

salivary:-

GeneChip

uterus:3.93

placenta:3.54

prostate:3.51

ovary:4.01

testis:7.03

heart:3.96

muscle:4

esophagus:3.86

stomach:3.74

intestine:3.87

colon:3.86

liver/hepato:3.93

lung:3.82

bladder:-

kidney:3.79

pituitary:4.67

thyroid/parathyroid:3.57

adrenal gland:6.54

pancreas:4.40

breast:3.83

salivary:3.93

CAGE

uterus:0.48

placenta:0

prostate:0.21

ovary:0.47

testis:3.20

heart:0

muscle:0

esophagus:0

stomach:-

intestine:0.07

colon:0

liver/hepato:0

lung:0

bladder:0

kidney:0

pituitary:0.38

thyroid/parathyroid:0

adrenal gland:-

pancreas:0.58

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.22

ovary:0.61

testis:2.44

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.03

liver/hepato:0

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0.01

adrenal gland:0.05

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_000475
Gene ID	190
Unigene ID	Hs.268490
Probe set ID	206645_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000169297
GTEx ID	ENSG00000169297

Orthologous Gene

Mouse[1]	NM_007430
Rat [0]

Chromosomal Region

Xp21.2 [30,322,323 - 30,327,715]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001723

Steroid hormone receptor

Gene Ontology (GO ID)

Biological Process

GO:0030325	adrenal gland development
GO:0010467	gene expression
GO:0008406	gonad development
GO:0021854	hypothalamus development
GO:0030522	intracellular receptor-mediated signaling pathway
GO:0033327	Leydig cell differentiation
GO:0008584	male gonad development
GO:0030238	male sex determination
GO:0045596	negative regulation of cell differentiation
GO:0033144	negative regulation of steroid hormone receptor signaling pathway
GO:0043433	negative regulation of transcription factor activity
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0021983	pituitary gland development
GO:0008104	protein localization
GO:0006950	response to stress
GO:0060008	Sertoli cell differentiation
GO:0007283	spermatogenesis
GO:0006694	steroid biosynthetic process
GO:0006367	transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005737	cytoplasm
GO:0016020	membrane
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0042788	polysomal ribosome

Molecular Function

GO:0050682	AF-2 domain binding
GO:0003677	DNA binding
GO:0032448	DNA hairpin binding
GO:0004879	ligand-dependent nuclear receptor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0042803	protein homodimerization activity
GO:0003723	RNA binding
GO:0043565	sequence-specific DNA binding
GO:0003707	steroid hormone receptor activity
GO:0035258	steroid hormone receptor binding
GO:0003714	transcription corepressor activity
GO:0008134	transcription factor binding

nuclear receptor subfamily 0, group B, member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function