endothelin receptor type B

Synonym

endothelin receptor type B, HSCR, Endothelin B receptor precursor, ET-B, ABCDS, HSCR2, EDNRB, ETB, ETRB, Endothelin receptor Non-selective type

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:55.70

cerebellum:188.90

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:92

spine:224.60

retina:-

eye:76.40

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:37.80

thymus:-

bone marrow:-

adipose:-

bone:-

skin:72

GeneChip

cerebrum:5.62

cerebellum:4.76

brain stem:5.76

corpus callosum/glia:5.27

pineal gland:-

peripheral nerve:7.18

spine:7.49

retina:-

eye:-

artery/aorta:5.42

vein:5.52

lymphnode:5.36

peripheral blood:-

spleen:5.52

thymus:4.36

bone marrow:4.21

adipose:6.56

bone:-

skin:5.49

CAGE

cerebrum:3.75

cerebellum:-

brain stem:4.08

corpus callosum/glia:3.89

pineal gland:2.42

peripheral nerve:-

spine:4.76

retina:-

eye:-

artery/aorta:1.94

vein:2.91

lymphnode:2.87

peripheral blood:-

spleen:4.00

thymus:0.83

bone marrow:-

adipose:4.45

bone:-

skin:-

RNA-seq

cerebrum:0

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.43

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.34

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:27.30

placenta:222.20

prostate:123.90

ovary:37.30

testis:38.90

heart:76.60

muscle:-

esophagus:-

stomach:21.20

intestine:162

colon:-

liver/hepato:10.60

lung:63.50

bladder:-

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:115.60

breast:9.30

salivary:-

GeneChip

uterus:5.26

placenta:7.20

prostate:5.71

ovary:4.49

testis:4.18

heart:6.42

muscle:4.36

esophagus:4.58

stomach:5.59

intestine:5.55

colon:5.47

liver/hepato:6.04

lung:7.32

bladder:-

kidney:5.55

pituitary:4.88

thyroid/parathyroid:5.79

adrenal gland:6.67

pancreas:5.55

breast:5.64

salivary:7.29

CAGE

uterus:2.91

placenta:4.15

prostate:3.20

ovary:2.95

testis:2.25

heart:3.58

muscle:3.19

esophagus:2.79

stomach:-

intestine:3.23

colon:2.43

liver/hepato:3.79

lung:4.14

bladder:3.44

kidney:4.27

pituitary:2.10

thyroid/parathyroid:3.45

adrenal gland:-

pancreas:2.08

breast:4.40

salivary:2.80

RNA-seq

uterus:-

placenta:-

prostate:0.63

ovary:0.28

testis:0.04

heart:0

muscle:1.10

esophagus:-

stomach:-

intestine:-

colon:0.68

liver/hepato:0.41

lung:1.27

bladder:-

kidney:1.19

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:1.57

pancreas:-

breast:0.67

salivary:-

IDs

Refseq ID	NM_003991
Gene ID	1910
Unigene ID	Hs.82002
Probe set ID	206701_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000136160
GTEx ID	ENSG00000136160

Orthologous Gene

Mouse[4]	NM_001136061, NM_007904
Rat [0]

Chromosomal Region

13q22.3 [78,469,616 - 78,493,903]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000276	7TM GPCR, rhodopsin-like
IPR001556	Bombesin receptor
IPR001112	Endothelin B receptor
IPR000499	Endothelin receptor
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007200	activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger
GO:0007568	aging
GO:0007166	cell surface receptor linked signal transduction
GO:0071222	cellular response to lipopolysaccharide
GO:0019934	cGMP-mediated signaling
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0048484	enteric nervous system development
GO:0042045	epithelial fluid transport
GO:0048246	macrophage chemotaxis
GO:0030318	melanocyte differentiation
GO:0007194	negative regulation of adenylate cyclase activity
GO:0043066	negative regulation of apoptosis
GO:0032269	negative regulation of cellular protein metabolic process
GO:0014043	negative regulation of neuron maturation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0007399	nervous system development
GO:0001755	neural crest cell migration
GO:0007422	peripheral nervous system development
GO:0008284	positive regulation of cell proliferation
GO:0060406	positive regulation of penile erection
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0007497	posterior midgut development
GO:0008217	regulation of blood pressure
GO:0050678	regulation of epithelial cell proliferation
GO:0006885	regulation of pH
GO:0051930	regulation of sensory perception of pain
GO:0014070	response to organic cyclic substance
GO:0048265	response to pain
GO:0019233	sensory perception of pain
GO:0042310	vasoconstriction
GO:0042311	vasodilation
GO:0014826	vein smooth muscle contraction

Cellular Component

GO:0005887	integral to plasma membrane
GO:0045121	membrane raft
GO:0031965	nuclear membrane
GO:0005886	plasma membrane

Molecular Function

GO:0004962	endothelin receptor activity
GO:0017046	peptide hormone binding
GO:0005515	protein binding
GO:0031702	type 1 angiotensin receptor binding

endothelin receptor type B

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function